Global COVID-19 Pandemic Waves: Limited Lessons Learned Worldwide over the Past Year [0.03%]
全球COVID-19疫情浪潮：过去一年的有限经验教训
Yongyue Wei,Jinxing Guan,Xiao Ning et al.
Yongyue Wei et al.
The occurrence of coronavirus disease 2019 (COVID-19) was followed by a small burst of cases around the world; afterward, due to a series of emergency non-pharmaceutical interventions (NPIs), the increasing number of confirmed cases slowed ...
A Vaccine Based on the Receptor-Binding Domain of the Spike Protein Expressed in Glycoengineered Pichia pastoris Targeting SARS-CoV-2 Stimulates Neutralizing and Protective Antibody Responses [0.03%]
基于糖基工程毕赤酵母表达的S蛋白受体结合域区制备的SARS-CoV-2疫苗可激发中和保护性抗体免疫应答
Bo Liu,Ying Yin,Yuxiao Liu et al.
Bo Liu et al.
In 2020 and 2021, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus, caused a global pandemic. Vaccines are expected to reduce the pressure of prevention and control, and have become the most effective strate...
Bradley J Edelman,Nessa Johnson,Abbas Sohrabpour et al.
Bradley J Edelman et al.
In this paper, we review the current state-of-the-art techniques used for understanding the inner workings of the brain at a systems level. The neural activity that governs our everyday lives involves an intricate coordination of many proce...
Identification of Monocytes Associated with Severe COVID-19 in the PBMCs of Severely Infected Patients Through Single-Cell Transcriptome Sequencing [0.03%]
通过单细胞转录组测序鉴定严重感染患者外周血单个核细胞中与重症新冠肺炎相关的单核细胞
Yan Zhang,Shuting Wang,He Xia et al.
Yan Zhang et al.
Understanding the immunological characteristics of monocytes-including the characteristics associated with fibrosis-in severe coronavirus disease 2019 (COVID-19) is crucial for understanding the pathogenic mechanism of the disease and preve...
Dean T Jamison,Kin Bing Wu
Dean T Jamison
Coronavirus disease 2019 (COVID-19) deaths per million population in the countries of the West had often exceeded those in the countries of the East by factor of 100 by May 2021. In this paper, we refer to the West as represented by the Uni...
Enhancing the Surface Properties of a Bioengineered Anterior Cruciate Ligament Matrix for Use with Point-of-Care Stem Cell Therapy [0.03%]
改善生物工程前交叉韧带基质的表面性质以配合现场干细胞治疗使用
Xiaohua Yu,Paulos Y Mengsteab,Ganesh Narayanan et al.
Xiaohua Yu et al.
We have previously developed a poly(L-lactic) acid (PLLA) bioengineered anterior cruciate ligament (ACL) matrix that has demonstrated enhanced healing when seeded with primary ACL cells prior to implantation in a rabbit model, as compared w...
Next Steps for Efficacy Evaluation in Clinical Trials of COVID-19 Vaccines [0.03%]
新冠肺炎疫苗临床试验疗效评价的下一步措施
Hu-Dachuan Jiang,Li Zhang,Jing-Xin Li et al.
Hu-Dachuan Jiang et al.
Chen Wang,Weizhong Yang
Chen Wang
A Scenario-Based Evaluation of COVID-19-Related Essential Clinical Resource Demands in China [0.03%]
中国与COVID-19相关的必需临床资源需求的场景评估
Ting Zhang,Qing Wang,Zhiwei Leng et al.
Ting Zhang et al.
The coronavirus disease 2019 (COVID-19) pandemic is a global crisis, and medical systems in many countries are overwhelmed with supply shortages and increasing demands to treat patients due to the surge in cases and severe illnesses. This s...
Temporal Profiles of Antibody Responses, Cytokines, and Survival of COVID-19 Patients: A Retrospective Cohort [0.03%]
COVID-19患者抗体反应、细胞因子和生存率的时序特征：回顾性队列研究
Li Liu,Heng-Gui Chen,Ying Li et al.
Li Liu et al.
The longitudinal immunologic status of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected patients and its association with the clinical outcome are barely known. Thus, we sought to analyze the temporal profiles of specif...