Ginsenoside Rg1 promotes non-rapid eye movement sleep via inhibition of orexin neurons of the lateral hypothalamus and corticotropin-releasing hormone neurons of the paraventricular hypothalamic nucleus [0.03%]
人参皂苷Rg1通过抑制下丘脑外侧腹腔室催产素神经元和视上核促肾上腺皮质激素释放激素神经元促进非快速眼动睡眠
Yi-Yuan Wang,Yi Wu,Ke-Wei Yu et al.
Yi-Yuan Wang et al.
Objective: This study investigates the sleep-modulating effects of ginsenoside Rg1 (Rg1, C42H72O14), a key bioactive component of ginseng, and elucidates its underlying mechanisms. ...
A herbal pair of Scutellaria barbata D. Don and Scleromitrion diffusum (Willd.) R.J. Wang induced ferroptosis in ovarian cancer A2780 cells via inducing heme catabolism and ferritinophagy [0.03%]
一枝黄花与毛叶地不容药对通过诱导血红素分解代谢及铁死亡自噬发挥抗卵巢癌A2780细胞增殖作用
Zhen Wang,Min Liu,Guang-Xing Li et al.
Zhen Wang et al.
Objective: Despite the combination of Scutellaria barbata D. Don and Scleromitrion diffusum (Willd.) R.J. Wang (SB-SD) being a recognized Chinese medicinal herbal pair that is commonly used in the treatment of ovarian can...
Jiedu recipe, a compound Chinese herbal medicine, suppresses hepatocellular carcinoma metastasis by inhibiting the release of tumor-derived exosomes in a hypoxic microenvironment [0.03%]
解毒活血汤通过抑制低氧微环境中肿瘤来源的外泌体释放来抑制肝癌转移
Wen-Tao Jia,Shuang Xiang,Jin-Bo Zhang et al.
Wen-Tao Jia et al.
Objective: Tumor-derived exosomes (TDEs) play crucial roles in intercellular communication. Hypoxia in the tumor microenvironment enhances secretion of TDEs and accelerates tumor metastasis. Jiedu recipe (JR), a tradition...
Ginsenoside Rh1 regulates the immune microenvironment of hepatocellular carcinoma via the glucocorticoid receptor [0.03%]
人参皂苷Rh1通过糖皮质激素受体调节肝细胞癌的免疫微环境
Xiong-Hui Wang,Ya-Lan Fu,Yan-Nan Xu et al.
Xiong-Hui Wang et al.
Objective: Ginsenoside Rh1 (G-Rh1) has been confirmed to inhibit the growth of breast cancer and colon cancer, but its therapeutic effect on hepatocellular carcinoma (HCC) is unclear. This study investigates the therapeut...
A comprehensive overview on antiviral effects of baicalein and its glucuronide derivative baicalin [0.03%]
黄芩素及其葡糖苷衍生物黄芩苷的抗病毒作用综述
Xin-Yang Liu,Wei Xie,He-Yang Zhou et al.
Xin-Yang Liu et al.
Natural product-based antiviral candidates have received significant attention. However, there is a lack of sufficient research in the field of antivirals to effectively combat patterns of drug resistance. Baicalein and its glucuronide deri...
Effectiveness and safety of adjunctive non-drug measures in improving respiratory symptoms among patients with severe COVID-19: A multicenter randomized controlled trial [0.03%]
改善重症新冠肺炎患者呼吸症状的非药物辅助治疗的有效性和安全性——一项多中心随机对照试验
Xuan Yin,Zhu Jin,Feng Li et al.
Xuan Yin et al.
Background: The outbreak of coronavirus disease 2019 (COVID-19) infection posed a huge threat and burden to public healthcare in late 2022. Non-drug measures of traditional Chinese medicine (TCM), such as acupuncture, cup...
Randomized Controlled Trial
Journal of integrative medicine. 2024 Nov;22(6):637-644. DOI:10.1016/j.joim.2024.09.002 2024
Luteolin protects against myocardial ischemia/reperfusion injury by reducing oxidative stress and apoptosis through the p53 pathway [0.03%]
黄酮类化合物山柰酚通过p53途径减少氧化应激和凋亡来保护心肌免受缺血/再灌注损伤
Pan Zhai,Xiao-Hu Ouyang,Meng-Ling Yang et al.
Pan Zhai et al.
Objective: Myocardial ischemia/reperfusion injury (MIRI) is an obstacle to the success of cardiac reperfusion therapy. This study explores whether luteolin can mitigate MIRI by regulating the p53 signaling pathway. ...
Clinical efficacy of Xuebijing injection for the treatment of sepsis: A retrospective cohort study [0.03%]
血必净注射液治疗脓毒症临床疗效观察：回顾性队列研究
Zhao-Tang Gong,Hong-Xin Yang,Ben-Ben Zhu et al.
Zhao-Tang Gong et al.
Objective: The objective of this study was to investigate the clinical efficacy and safety of treating sepsis patients with Xuebijing injection (XBJI). Me...
Hongjin Xiaojie Capsule, a Chinese patent medicine, for treating moderate to severe cyclical breast pain: A single-blind randomized controlled trial [0.03%]
红金消结胶囊治疗中重度经期乳腺疼痛的单盲随机对照试验
Qiong Zhang,Ying-Yi Fan,Xue-Qing Wu et al.
Qiong Zhang et al.
Background: Moderate to severe breast pain has major effects on the quality of life for patients. Patent Chinese medicines are widely used in the treatment of breast pain due to their stable dosage form and good efficacy....
Randomized Controlled Trial
Journal of integrative medicine. 2024 Sep;22(5):552-560. DOI:10.1016/j.joim.2024.08.005 2024
Stimuli-evoked NOergic molecules and neuropeptides at acupuncture points and the gracile nucleus contribute to signal transduction of propagated sensation along the meridian through the dorsal medulla-thalamic pathways [0.03%]
针刺刺激激活的末梢N-乙酰基半胱氨酸和神经肽通过背侧脑干-丘脑通路向中枢传递信息
Sheng-Xing Ma
Sheng-Xing Ma
Numerous studies from different international groups have demonstrated that sensations can be propagated along acupuncture channel pathways. The propagated sensation along the channel pathway (PSCP) can be elicited by electroacupuncture (EA...