Bioactive components of Xinyang and Xinyin tablets for treating chronic heart failure: Pharmacokinetics, network pharmacology and experimental validation [0.03%]
信阳茶和信仁茶治疗慢性心力衰竭的活性成分：药动学、网络药理学及实验验证
Yan-Ling Lan,Si-Mian Chen,Bin-Xin Dai et al.
Yan-Ling Lan et al.
Objective: Xinyang Tablet (XYAT) and Xinyin Tablet (XYIT) have been used to treat chronic heart failure (CHF) for 20 years. This study investigated their pharmacodynamic material basis and underlying mechanisms of action....
Neuroprotective activity of mung bean (Vigna radiata) coat extract via AMPK-dependent autophagy in Alzheimer's and Parkinson's models [0.03%]
绿豆衣提取物通过AMPK依赖性自噬对抗阿尔茨海默病和帕金森病的神经保护作用
Zhi-Xiong Chen,Fang-Ping Wang,Ya-Ping Li et al.
Zhi-Xiong Chen et al.
Objective: Alzheimer's disease (AD) and Parkinson's disease (PD) are major age-related neurodegenerative disorders that currently lack effective disease-modifying therapies. This study investigated the neuroprotective pot...
Protective effects of Prunella vulgaris polysaccharides against herpes simplex virus type 1 infection through the STING-TBK1-IRF3 pathway [0.03%]
耳叶牛膝草多糖通过STING-TBK1-IRF3信号通路抵御HSV-1感染的作用及机制研究
Yi-Bo Zhang,Lin Xu,Man Yuan et al.
Yi-Bo Zhang et al.
Objective: Enhancing innate immunity through interferons (IFNs) and IFN-stimulated genes (ISGs) offers a promising strategy for preventing herpes simplex virus type 1 (HSV-1) infection. Prunella vulgaris L., a medicinal h...
Aconitum coreanum (H.Lév l.) Rapaics exerts neuroprotective effects on cerebral ischemic stroke by inhibiting autophagy through the AMPK/mTOR/ULK1 pathway [0.03%]
远志乌头通过AMPK/mTOR/ULK1信号通路抑制自噬对缺血性卒中的神经保护作用
Yue Liu,Yang Qu,Qian Cai
Yue Liu
Objective: Cerebral ischemic stroke (CIS) induces neuronal damage and activates neuronal autophagy through diverse mechanisms. Autophagy exerts adverse effects in acute neurological disorders, leading to neuronal apoptosi...
Electroacupuncture regulates histone acetylation to improve spatial memory impairment in rats with chronic cerebral hypoperfusion [0.03%]
电针通过调节组蛋白乙酰化改善慢性脑低灌注大鼠空间记忆缺损
Yan-Yi Ding,Wen-Ju Wang,Le-Wen Chen et al.
Yan-Yi Ding et al.
Objective: Chronic cerebral hypoperfusion (CCH) can cause long-term changes in gene expression and increase susceptibility to spatial memory impairment, in which the histone acetylation plays a crucial role. Studies have ...
Gastroprotective activity of Talinum paniculatum (Jacq.) Gaertn. in mice: An ethnopharmacological validation [0.03%]
聚基南蛇藤的族药物验证研究及其在小鼠中的胃保护作用
Kessy Gabrielly Pegoraro Correa,Marcella do Carmo Barroso de Siqueira,Mariana Zanovello et al.
Kessy Gabrielly Pegoraro Correa et al.
Objective: Gastric ulcers are a global health issue, often occurring in the stomach or duodenum and causing tissue necrosis. Talinum paniculatum (Jacq.) Gaertn (Erva-gorda) is used in traditional medicine for treating gas...
Safety of herbal medicines in Korean medicine clinics in Republic of Korea: A nationwide retrospective longitudinal cohort study [0.03%]
韩国韩医诊所草药的安全性全国范围回顾性纵向队列研究
Eunbyul Cho,Mi Mi Ko,Changsop Yang et al.
Eunbyul Cho et al.
Objective: Laboratory tests are commonly used in Korean medicine (KM) clinics to monitor the safety of herbal medicine (HM). Although the incidence of herb-induced liver injury (HILI) in Republic of Korea has been reporte...
Yin-yang dynamics in wound inflammation: yin and yang manifestations of inflammatory substances [0.03%]
伤口炎症中的阴阳动态变化及其炎性物质的阴阳表现形式研究进展
Yue-Fei Geng,Xiu-Ying Ma,Yan Ge et al.
Yue-Fei Geng et al.
Over the past three decades, a growing body of research has been dedicated to the integration of traditional Chinese medicine (TCM) and modern medicine, highlighting the complementary benefits of both disciplines. However, in the context of...
Acupuncture is an effective alternative to medication for migraine: An umbrella review [0.03%]
针灸可有效替代偏头痛的药物治疗：伞式评价研究
Paulo Alexandre Pereira,Carlos Miguel Marto,Bárbara Oliveiros et al.
Paulo Alexandre Pereira et al.
Background: Migraine is a highly prevalent primary headache disorder that impacts individuals and societies around the globe. Acupuncture can be used in migraine treatment and prevention due to its analgesic effects, safe...
Collision of Chinese medicine and materials science: Interdisciplinary biomaterials' perspectives [0.03%]
中医药与材料科学的碰撞：交叉学科生物材料的新视角
Wei-Kang Luo,Xiao-Hang Guo,Li-Na Cao et al.
Wei-Kang Luo et al.
The integration of materials science and Chinese medicine (CM) has emerged as a significant interdisciplinary field, playing a crucial role in enhancing the pharmacodynamics of CM and its derived small molecules. This field introduces novel...