EBV-associated lymphoproliferative disease post-CAR-T cell therapy [0.03%]
CAR-T细胞治疗后与EB病毒相关的淋巴增生性疾病
Shiyuan Zhang,Xiaoxi Zhou,Shangkun Zhang et al.
Shiyuan Zhang et al.
Epstein-Barr virus (EBV)-associated lymphoproliferative diseases (EBV-LPDs) are common complications that occur after solid organ transplantation or allogeneic hematopoietic stem-cell transplantation (HSCT). However, their occurrence and tr...
Guangbiao Zhou,Saijuan Chen,Zongjiu Zhang et al.
Guangbiao Zhou et al.
Insights into optimizing exosome therapies for acute skin wound healing and other tissue repair [0.03%]
优化外泌体疗法以促进急性皮肤伤口愈合及其他组织修复的见解
Tianjing Sun,Mo Li,Qi Liu et al.
Tianjing Sun et al.
Exosome therapy holds great promise as a novel approach to improve acute skin wound healing. This review provides a comprehensive overview of the current understanding of exosome biology and its potential applications in acute skin wound he...
Epidemiology, pathogenesis, and management of Coronavirus disease 2019-associated stroke [0.03%]
2019冠状病毒病相关卒中的流行病学、病因和治疗
Lu Liu,Chenxia Zhou,Huimin Jiang et al.
Lu Liu et al.
The Coronavirus disease 2019 (COVID-19) epidemic has triggered a huge impact on healthcare, socioeconomics, and other aspects of the world over the past three years. An increasing number of studies have identified a complex relationship bet...
Small-molecule anti-COVID-19 drugs and a focus on China's homegrown mindeudesivir (VV116) [0.03%]
小分子抗COVID-19药物及聚焦中国本土药物候选者mindeudesivir (VV116)
Qiuyu Cao,Yi Ding,Yu Xu et al.
Qiuyu Cao et al.
The coronavirus disease 2019 (COVID-19) pandemic has stimulated tremendous efforts to develop therapeutic agents that target severe acute respiratory syndrome coronavirus 2 to control viral infection. So far, a few small-molecule antiviral ...
Unraveling the complex roles of macrophages in obese adipose tissue: an overview [0.03%]
解开巨噬细胞在肥胖脂肪组织中的复杂作用:综述
Chang Peng,Jun Chen,Rui Wu et al.
Chang Peng et al.
Macrophages, a heterogeneous population of innate immune cells, exhibit remarkable plasticity and play pivotal roles in coordinating immune responses and maintaining tissue homeostasis within the context of metabolic diseases. The activatio...
Multi-omics joint analysis revealed the metabolic profile of retroperitoneal liposarcoma [0.03%]
多组学联合分析揭示了腹膜后脂肪肉瘤的代谢谱型
Fuan Xie,Yujia Niu,Lanlan Lian et al.
Fuan Xie et al.
Retroperitoneal liposarcoma (RLPS) is the main subtype of retroperitoneal soft sarcoma (RSTS) and has a poor prognosis and few treatment options, except for surgery. The proteomic and metabolic profiles of RLPS have remained unclear. The ai...
Cytokine storm and translating IL-6 biology into effective treatments for COVID-19 [0.03%]
细胞因子风暴及将IL-6生物学特性转变为COVID-19的有效治疗方法
Tiantian Li,Dongsheng Wang,Haiming Wei et al.
Tiantian Li et al.
As of May 3, 2023, the Coronavirus disease 2019 (COVID-19) pandemic has resulted in more than 760 million confirmed cases and over 6.9 million deaths. Several patients have developed pneumonia, which can deteriorate into acute respiratory d...
Pathogen evolution, prevention/control strategy and clinical features of COVID-19: experiences from China [0.03%]
病原进化,预防/控制策略和COVID-19的临床特征:来自中国的经验
Dong Wei,Yusang Xie,Xuefei Liu et al.
Dong Wei et al.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was reported at the end of 2019 as a worldwide health concern causing a pandemic of unusual viral pneumonia and many other organ damages, which was defined by the World Health Org...
Decitabine induces IRF7-mediated immune responses in p53-mutated triple-negative breast cancer: a clinical and translational study [0.03%]
地西他滨诱导p53突变型三阴性乳腺癌中的IRF7介导的免疫反应:临床与转化研究
Haoyu Wang,Zhengyuan Wang,Zheng Wang et al.
Haoyu Wang et al.
p53 is mutated in half of cancer cases. However, no p53-targeting drugs have been approved. Here, we reposition decitabine for triple-negative breast cancer (TNBC), a subtype with frequent p53 mutations and extremely poor prognosis. In a re...