Sex-Specific Cardiovascular Risks and Mortality in Patients with Panhypopituitarism: A Nationwide Cohort Study [0.03%]
原发性 adrenal insufficiency全人群队列研究中的性别特异性心血管风险和死亡率
Seung Shin Park,Hyunmook Jeong,Chang Ho Ahn et al.
Seung Shin Park et al.
Background: Panhypopituitarism is a condition of combined deficiency of multiple pituitary hormones, which requires lifelong hormone replacement therapy. Hormone deficiency or inadequate hormone replacement may contribute...
Combined PD-1 and CTLA-4 Blockade Increases the Risks of Multiple Pituitary Hormone Deficiency and Isolated Adrenocorticotropic Deficiency: A Prospective Study [0.03%]
纳武单抗和伊匹单抗联合治疗增加多激素缺乏症和孤立性促肾上腺皮质激素缺乏症的发病风险：一项前瞻性研究
Shintaro Iwama,Tomoko Kobayashi,Tetsushi Izuchi et al.
Shintaro Iwama et al.
Background: Anti-cytotoxic T-lymphocyte antigen-4 antibody (CTLA-4-Ab) monotherapy induces two types of pituitary immunerelated adverse events (irAEs): multiple pituitary hormone deficiency (Multi-D; impairment of ≥2 ant...
Effects of Sequential Anti-Resorptive Agents on Bone Mineral Density Following Denosumab Withdrawal: A Multicenter Real-World Study in Korea (MAXCARE Study) [0.03%]
韩国多中心真实世界研究：地诺单抗停药后序贯抗吸收剂对骨密度的影响（MAXCARE 研究）
Jeonghoon Ha,Kyong Yeun Jung,Kyoung Jin Kim et al.
Jeonghoon Ha et al.
Background: Denosumab is a potent anti-resorptive agent widely used for osteoporosis. However, its discontinuation results in a 'rebound phenomenon' of rapid bone loss, necessitating transition to alternative anti-resorpt...
Time to Insulin Therapy and Severe Hypoglycemia in Korean Adults Initially Diagnosed with Type 2 Diabetes: A Nationwide Study [0.03%]
韩国成人新诊断的2型糖尿病患者开始胰岛素治疗的时间与严重低血糖的关系：一项全国性研究
You-Bin Lee,Kyungdo Han,Bongsung Kim et al.
You-Bin Lee et al.
Background: We examined the distribution of time to insulin therapy (TIT) post-diabetes diagnosis and the hazard of severe hypoglycemia (SH) according to TIT in Korean adults initially diagnosed with type 2 diabetes (T2D)...
Comparison of the Effectiveness and Hypocalcemia Risk of Antiresorptive Agents in Patients with Hypercalcemia of Malignancy [0.03%]
不同抗吸收剂在恶性高钙血症患者中的疗效和低钙血症风险的比较
Sung Hye Kong,Seung Shin Park,Jung Hee Kim et al.
Sung Hye Kong et al.
Background: Hypercalcemia of malignancy (HCM), a major metabolic complication of cancer, is often managed with bisphosphonates (BP) and, increasingly, with denosumab. We aimed to compare the effectiveness and safety of de...
Long-Term Prognosis and Systemic Impact of Acromegaly: Analyses Utilizing Korean National Health Insurance Data [0.03%]
韩国国民健康保险数据利用的肢端肥大症长期预后和全身影响分析
Sangmo Hong,Kyungdo Han,Cheol-Young Park
Sangmo Hong
Acromegaly is a rare endocrine disorder caused by excessive growth hormone secretion. Its low prevalence poses challenges in studying its long-term prognosis and systemic effects. To address this research gap, we conducted five studies usin...
Gestational Diabetes Mellitus: Mechanisms Underlying Maternal and Fetal Complications [0.03%]
妊娠糖尿病：母体和胎儿并发症的机制研究
Jooyeop Lee,Na Keum Lee,Joon Ho Moon
Jooyeop Lee
Gestational diabetes mellitus (GDM) affects over 10% of all pregnancies, both in Korea and worldwide. GDM not only increases the risk of adverse pregnancy outcomes such as preeclampsia, preterm birth, macrosomia, neonatal hypoglycemia, and ...
Prognostic Indicators and Comparative Treatment Outcomes in High-Risk Thyroid Cancer with Laryngotracheal Invasion [0.03%]
喉气管侵犯高风险甲状腺癌的预后指标及治疗结局比较分析
Eman A Toraih,Jessan A Jishu,Mohammad H Hussein et al.
Eman A Toraih et al.
Background: Laryngotracheal invasion occurs in a subset of patients with well-differentiated thyroid cancer (WDTC) and is associated with a poor prognosis. We aimed to analyze patterns and predictors/outcomes related to t...
Risk of Osteoporotic Fractures among Patients with Thyroid Cancer: A Nationwide Population-Based Cohort Study [0.03%]
甲状腺癌患者骨质疏松性骨折的风险：全国人群队列研究
Eu Jeong Ku,Won Sang Yoo,Yu Been Hwang et al.
Eu Jeong Ku et al.
Background: The associations between thyroid cancer and skeletal outcomes have not been thoroughly investigated. We aimed to investigate the risk of osteoporotic fractures in patients with thyroid cancer compared to that ...