Retrospective Analysis of the Efficacy of Dapagliflozin in Patients with Type 2 Diabetes in a Primary Clinic in Korea [0.03%]
韩国一家初级保健诊所2型糖尿病患者达格列净疗效的回顾性分析
Sang Hyun Park,Young Ju Choi,Eun Jung Rhee et al.
Sang Hyun Park et al.
Background: We aimed to retrospectively analyze the efficacy of 10 mg dapagliflozin (DAPA), which is a sodium-glucose cotransporter-2 inhibitor, in Korean patients with type 2 diabetes who visited a primary diabetes clini...
Medical Treatment with Somatostatin Analogues in Acromegaly: Position Statement [0.03%]
生长抑素类似物治疗肢端肥大症的专家共识声明
Sang Ouk Chin,Cheol Ryong Ku,Byung Joon Kim et al.
Sang Ouk Chin et al.
The Korean Endocrine Society (KES) published clinical practice guidelines for the treatment of acromegaly in 2011. Since then, the number of acromegaly cases, publications on studies addressing medical treatment of acromegaly, and demands f...
Sun H Kim,Fahim Abbasi
Sun H Kim
Gerald Reaven was often called the "father of insulin resistance." On the 1-year anniversary of his death in 2018, we challenge three myths associated with insulin resistance: metformin improves insulin resistance; measurement of waist circ...
Implications of Mitochondrial Unfolded Protein Response and Mitokines: A Perspective on Fatty Liver Diseases [0.03%]
线粒体未折叠蛋白反应和米托昆的含义：脂肪肝病的新视角
Hyon Seung Yi
Hyon Seung Yi
The signaling network of the mitochondrial unfolded protein response (UPRmt) and mitohormesis is a retrograde signaling pathway through which mitochondria-to-nucleus communication occurs in organisms. Recently, it has been shown that the UP...
Wilmar M Wiersinga
Wilmar M Wiersinga
Whether or not Graves' hyperthyroidism can be really cured, depends on the definition of "cure." If eradication of thyroid hormone excess suffices for the label "cure," then all patients can be cured because total thyroidectomy or high dose...
So Young Park,Myeong Han Seo,Sihoon Lee
So Young Park
The identification of disease-causing genetic variations is an important goal in the field of genetics. Advancements in genetic technology have changed scientific knowledge and made it possible to determine the basic mechanism and pathogene...
Young Shin Song,Young Joo Park
Young Shin Song
Since the release of The Cancer Genome Atlas study of papillary thyroid carcinoma (PTC) in 2014, additional genomic studies of differentiated thyroid carcinoma (DTC) using massively-parallel sequencing (MPS) have been published. Recent adva...
Mouse Models as a Tool for Understanding Progression in BrafV600E-Driven Thyroid Cancers [0.03%]
BrafV600E诱导的甲状腺癌进展的小鼠模型研究
Iñigo Landa,Jeffrey A Knauf
Iñigo Landa
The development of next generation sequencing (NGS) has led to marked advancement of our understanding of genetic events mediating the initiation and progression of thyroid cancers. The NGS studies have confirmed the previously reported hig...
99mTc-Pertechnetate Scintigraphy Predicts Successful Postoperative Ablation in Differentiated Thyroid Carcinoma Patients Treated with Low Radioiodine Activities [0.03%]
99mTc-Pertechnetate闪烁显像可预测低活度放射性碘治疗分化型甲状腺癌患者术后清甲效果
Luca Giovanella,Gaetano Paone,Teresa Ruberto et al.
Luca Giovanella et al.
Background: Postoperative routine radioiodine (RAI) treatment is currently debated for patients with low-risk differentiated thyroid carcinoma (DTC) patients. If performed, a low ¹³¹I activity (i.e., 1 to 2 GBq) is rec...