Cigarette Smoke Extract-induced Reduction in Migration and Contraction in Normal Human Bronchial Smooth Muscle Cells [0.03%]
正常人支气管平滑肌细胞中 cigarette smoke extract 诱导的迁移和收缩降低现象
Chul Ho Yoon,Hye-Jin Park,Young-Woo Cho et al.
Chul Ho Yoon et al.
The proliferation, migration, cytokine release, and contraction of airway smooth muscle cells are key events in the airway remodeling process that occur in lung disease such as asthma, chronic obstruction pulmonary disease, and cancer. Thes...
Blockade of ERK Phosphorylation in the Nucleus Accumbens Inhibits the Expression of Cocaine-induced Behavioral Sensitization in Rats [0.03%]
阻断伏核ERK磷酸化抑制cocaine诱导的行为敏感性表达
Seungwoo Kim,Joong-Keun Shin,Hyung Shin Yoon et al.
Seungwoo Kim et al.
Repeated administration of psychostimulants such as cocaine leads to the development of behavioral sensitization. Extracellular signal-Regulated Kinase (ERK), an enzyme important for long-term neuronal plasticity, has been implicated in suc...
Role of regulators of g-protein signaling 4 in ca signaling in mouse pancreatic acinar cells [0.03%]
Regulators of G-Protein Signaling 4 在小鼠胰腺泡细胞Ca信号转导中的作用
Soonhong Park,Syng-Ill Lee,Dong Min Shin
Soonhong Park
Regulators of G-protein signaling (RGS) proteins are regulators of Ca(2+) signaling that accelerate the GTPase activity of the G-protein α-subunit. RGS1, RGS2, RGS4, and RGS16 are expressed in the pancreas, and RGS2 regulates G-protein cou...
A Computational Model of the Temperature-dependent Changes in Firing Patterns in Aplysia Neurons [0.03%]
温度依赖的海兔神经元放电模式变化的计算模型
Nam Gyu Hyun,Kwang-Ho Hyun,Kwang-Beom Hyun et al.
Nam Gyu Hyun et al.
We performed experiments using Aplysia neurons to identify the mechanism underlying the changes in the firing patterns in response to temperature changes. When the temperature was gradually increased from 11℃ to 31℃ the firing patterns ch...
Inhibition of Inducible Nitric Oxide Synthase Attenuates Monosodium Urate-induced Inflammation in Mice [0.03%]
诱导型一氧化氮合酶的抑制作用能缓解尿酸钠引起的鼠类炎症反应
Tae-Jin Ju,Jin-Myoung Dan,Young-Je Cho et al.
Tae-Jin Ju et al.
The present study elucidated the effect of the selective inducible nitric oxide synthase (iNOS) inhibitor N(6)-(1-iminoethyl)-L-lysine (L-NIL) on monosodium urate (MSU) crystal-induced inflammation and edema in mice feet. L-NIL (5 or 10 mg/...
The Neuroprotective Potential of Cyanidin-3-glucoside Fraction Extracted from Mulberry Following Oxygen-glucose Deprivation [0.03%]
桑葚花色苷-3-半乳糖提取物对体外氧化葡萄糖剥夺损伤的神经保护作用研究
Mohammad Iqbal Hossain Bhuiyan,Hyun-Bok Kim,Seong Yun Kim et al.
Mohammad Iqbal Hossain Bhuiyan et al.
In this study, cyanidin-3-glucoside (C3G) fraction extracted from the mulberry fruit (Morus alba L.) was investigated for its neuroprotective effects against oxygen-glucose deprivation (OGD) and glutamate-induced cell death in rat primary c...
4-phenylbutyric Acid Regulates Collagen Synthesis and Secretion Induced by High Concentrations of Glucose in Human Gingival Fibroblasts [0.03%]
苯基丁酸调控高糖诱导的人牙龈纤维细胞内胶原的合成与分泌
Geum-Hwa Lee,Hyo-Won Oh,Hyun-Dae Lim et al.
Geum-Hwa Lee et al.
High glucose leads to physio/pathological alterations in diabetes patients. We investigated collagen production in human gingival cells that were cultured in high concentrations of glucose. Collagen synthesis and secretion were increased wh...
Vasorelaxing Activity of Ulmus davidiana Ethanol Extracts in Rats: Activation of Endothelial Nitric Oxide Synthase [0.03%]
峨眉榆叶梅乙醇提取物的 vasorelaxing 活性研究：内皮型一氧化氮合酶的活化作用
Eun Jung Cho,Myoung Soo Park,Sahng Seop Kim et al.
Eun Jung Cho et al.
Ulmus davidiana var. japonica Rehder (Urticales: Ulmaceae) (UD) is a tree widespread in northeast Asia. It is traditionally used for anticancer and anti-inflammatory therapy. The present study investigated the effect of an ethanol extract o...
The Protective Effect of Black Ginseng Against Transient Focal Ischemia-induced Neuronal Damage in Rats [0.03%]
黑人参对大鼠短暂性局灶缺血诱导的神经元损伤保护作用的效果研究
Hyun-Jung Park,Hyun Soo Shim,Kyung Soo Kim et al.
Hyun-Jung Park et al.
Black ginseng (BG) has been widely used as herbal treatment for improving physiological function. In order to investigate the neuroprotective action of this herbal medicine, we examined the influence of BG on the learning and memory of rats...
Chronic Opium Treatment Can Differentially Induce Brain and Liver Cells Apoptosis in Diabetic and Non-diabetic Male and Female Rats [0.03%]
慢性鸦片治疗可差异诱导糖尿病和非糖尿病大鼠的脑和肝细胞凋亡
Majid Asiabanha,Gholamreza Asadikaram,Amir Rahnema et al.
Majid Asiabanha et al.
It has been shown that some opium derivatives promote cell death via apoptosis. This study was designed to examine the influence of opium addiction on brain and liver cells apoptosis in male and female diabetic and non-diabetic Wistar rats....