Effects of Inositol 1,4,5-triphosphate on Osteoclast Differentiation in RANKL-induced Osteoclastogenesis [0.03%]
肌醇磷脂对RANKL诱导的破骨细胞生成的影响
Aran Son,Min Seuk Kim,Hae Jo et al.
Aran Son et al.
The receptor activator of NF-κB ligand (RANKL) signal is an activator of tumor necrosis factor receptor-associated factor 6 (TRAF6), which leads to the activation of NF-κB and other signal transduction pathways essential for osteoclastoge...
Bile Acid Inhibition of N-type Calcium Channel Currents from Sympathetic Ganglion Neurons [0.03%]
胆酸抑制交感神经节神经元N型钙通道电流的作用机制研究
Hye Kyung Lee,Kyoung Hwa Lee,Eui-Sic Cho
Hye Kyung Lee
Under some pathological conditions as bile flow obstruction or liver diseases with the enterohepatic circulation being disrupted, regurgitation of bile acids into the systemic circulation occurs and the plasma level of bile acids increases....
The characteristics of supramammillary cells projecting to the hippocampus in stress response in the rat [0.03%]
大鼠应激反应中向海马投射的supra-mammillary核细胞的特征
Woong Ki Choi,David Wirtshafter,Hyun-Jung Park et al.
Woong Ki Choi et al.
The hypothalamus-pituitary-adrenocortex (HPA) axis is the central mediator of the stress response. The supramammillary (SuM) region is relatively unique among the hypothalamic structures in that it sends a large, direct projection to the hi...
Effect of 5-FU and MTX on the Expression of Drug-resistance Related Cancer Stem Cell Markers in Non-small Cell Lung Cancer Cells [0.03%]
5-氟尿嘧啶和甲氨蝶呤对非小细胞肺癌细胞耐药相关癌干细胞标记物表达的影响
Hee Yi,Hee-Jung Cho,Soo-Min Cho et al.
Hee Yi et al.
Cancer stem cells (CSCs) are often characterized by the elevated expression of drug-resistance related stem-cell surface markers, such as CD133 and ABCG2. Recently, we reported that CSCs have a high level of expression of the IL-6 receptor ...
Hyun-Jung Kim,Chang Yun Jin
Hyun-Jung Kim
Because the average human life span has recently increased, the number of patients who are diagnosed with neurodegenerative diseases has escalated. Recent advances in stem cell research have given us access to unlimited numbers of multi-pot...
c-Fos Expression in the Nucleus of the Solitary Tract in Response to Salt Stimulation in Rats [0.03%]
盐刺激大鼠孤束核c-Fos表达分布变化研究
Yongho Kwak,Mee-Ra Rhyu,Sun Joon Bai et al.
Yongho Kwak et al.
Salt signals in tongue are relayed to the nucleus of the solitary tract (NST). This signaling is very important to determine whether to swallow salt-related nutrition or not and suggests some implications in discrimination of salt concentra...
Alteration of Ryanodine-receptors in Cultured Rat Aortic Smooth Muscle Cells [0.03%]
瑞安诺idine受体在培养的鼠主动脉平滑肌细胞中的改变
Eun Ji Kim,Dong Kwan Kim,Shin Hye Kim et al.
Eun Ji Kim et al.
Vascular smooth muscle cells can obtain a proliferative function in environments such as atherosclerosis in vivo or primary culture in vitro. Proliferation of vascular smooth muscle cells is accompanied by changes in ryanodine receptors (Ry...
Cytotoxicities and Quantitative Structure Activity Relationships of B13 Sulfonamides in HT-29 and A549 Cells [0.03%]
B13磺酰胺类化合物的细胞毒性及其量化结构活性关系研究
Seul Ki Chan Lee,Sang Min Park,Chaeuk Im
Seul Ki Chan Lee
B13 analogues are being considered as therapeutic agents for cancer cells, since B13 is a ceramide analogue and inhibits ceramidase to promote apoptosis in cancer cells. B13 sulfonamides are assumed to have biological activity similar to B1...
Spontaneous Oscillatory Rhythm in Retinal Activities of Two Retinal Degeneration (rd1 and rd10) Mice [0.03%]
两种视网膜退行小鼠（rd1和rd10）视网膜活动的自发振荡规律性研究
Yong Sook Goo,Kun No Ahn,Yeong Jun Song et al.
Yong Sook Goo et al.
Previously, we reported that besides retinal ganglion cell (RGC) spike, there is ~ 10 Hz oscillatory rhythmic activity in local field potential (LFP) in retinal degeneration model, rd1 mice. The more recently identified rd10 mice have a lat...
Nitric Oxide-mediated Relaxation by High K in Human Gastric Longitudinal Smooth Muscle [0.03%]
高钾介导的一氧化氮舒张反应在人胃纵行平滑肌中的作用
Young Chul Kim,Woong Choi,Hyo-Young Yun et al.
Young Chul Kim et al.
This study was designed to elucidate high-K(+)induced response of circular and longitudinal smooth muscle from human gastric corpus using isometric contraction. Contraction from circular and longitudinal muscle stripes of gastric corpus gre...