The Protective Effect of Eupatilin against Hydrogen Peroxide-Induced Injury Involving 5-Lipoxygenase in Feline Esophageal Epithelial Cells [0.03%]
猫食道黏膜上皮细胞中茋类成分欧帕帝林通过作用于5-脂氧合酶发挥抗氧化损伤保护效应的研究
Jae Chun Lim,Sun Young Park,Yoonjin Nam et al.
Jae Chun Lim et al.
In this study, we focused to identify whether eupatilin (5,7-dihydroxy-3',4',6-trimethoxyflavone), an extract from Artemisia argyi folium, prevents H(2)O(2)-induced injury of cultured feline esophageal epithelial cells. Cell viability was m...
Dae Hoon Kim,Young Chul Kim,Woong Choi et al.
Dae Hoon Kim et al.
This study was designed to elucidate high K(+)-induced relaxation in the human gastric fundus. Circular smooth muscle from the human gastric fundus greater curvature showed stretch-dependent high K(+) (50 mM)-induced contractions. However, ...
Effect of intensity of unconditional stimulus on reconsolidation of contextual fear memory [0.03%]
无条件刺激的强度对情境恐惧记忆再巩固的影响
Chuljung Kwak,Jun-Hyeok Choi,Joseph T Bakes et al.
Chuljung Kwak et al.
Memory reconsolidation is ubiquitous across species and various memory tasks. It is a dynamic process in which memory is modified and/or updated. In experimental conditions, memory reconsolidation is usually characterized by the fact that t...
Dipeptides Inhibit Melanin Synthesis in Mel-Ab Cells through Down-Regulation of Tyrosinase [0.03%]
二肽通过降低黑色素细胞中酪氨酸酶的表达来抑制黑色素合成
Hyun-E Lee,Eun-Hyun Kim,Hye-Ryung Choi et al.
Hyun-E Lee et al.
This study investigated the effects of proline-serine (PS) and valine-serine (VS) dipeptides on melanogenesis in Mel-Ab cells. Proline-serine and VS significantly inhibited melanin synthesis in a concentration-dependent manner, though neith...
Comparison of Neurite Outgrowth Induced by Erythropoietin (EPO) and Carbamylated Erythropoietin (CEPO) in Hippocampal Neural Progenitor Cells [0.03%]
比较 carbamylated 琥珀酸亚胺基 erythropoietin 和 erythropoietin 对海马神经元前体细胞突起生长的影响
Dong Hoon Oh,In Young Lee,Miyeon Choi et al.
Dong Hoon Oh et al.
A previous animal study has shown the effects of erythropoietin (EPO) and its non-erythropoietic carbamylated derivative (CEPO) on neurogenesis in the dentate gyrus. In the present study, we sought to investigate the effect of EPO on adult ...
A simple dosing scheme for intravenous busulfan based on retrospective population pharmacokinetic analysis in korean patients [0.03%]
基于回顾性群体药代动力学分析的静脉注射布舒芬在韩国患者中的简单给药方案
Sangmin Choe,Gayeong Kim,Hyeong-Seok Lim et al.
Sangmin Choe et al.
Busulfan is an antineoplastic agent with a narrow therapeutic window. A post-hoc population pharmacokinetic analysis of a prospective randomized trial for comparison of four-times daily versus once-daily intravenous busulfan was carried out...
Sung-Won Park,Kyung-Jong Won,Yong-Soo Lee et al.
Sung-Won Park et al.
HoxB4, a homeodomain-containing transcription factor, is involved in the expansion of hematopoietic stem cells and progenitor cells in vivo and in vitro, and plays a key role in regulating the balance between hematopoietic stem cell renewal...
The effect of methanol on the structural parameters of neuronal membrane lipid bilayers [0.03%]
甲醇对神经细胞膜脂质双层结构参数的影响
Hyung-Jin Joo,Shin-Ho Ahn,Hang-Rae Lee et al.
Hyung-Jin Joo et al.
The structures of the intact synaptosomal plasma membrane vesicles (SPMVs) isolated from bovine cerebral cortexs, and the outer and the inner monolayer separately, were evaluated with 1,6-diphenyl-1,3,5-hexatriene (DPH) and 1,3-di(1-pyrenyl...
The safety and pharmacokinetics of cyanidin-3-glucoside after 2-week administration of black bean seed coat extract in healthy subjects [0.03%]
黑豆皮提取物在健康志愿者中的安全性与药代动力学（用药两周）
Sangil Jeon,Seunghoon Han,Jongtae Lee et al.
Sangil Jeon et al.
We analyzed the pharmacokinetics of C3G on data from twelve subjects, after 2-week multiple dosing of black bean (Phaseolus vulgaris, Cheongjakong-3-ho) seed coat extract, using the mixed effect analysis method (NONMEM, Ver. 6.2), as well a...
Morphologic evidence of anti-tumor specificity of T cells activated by denritic cells derived from peripheral blood mononuclear cells of thyroid cancer patients [0.03%]
甲状腺癌外周血单个核细胞诱导的树突状细胞活化T细胞的抗肿瘤效应及其形态学依据研究
Dae-Heui Lee
Dae-Heui Lee
Recent studies suggest that immunization with autologous dendritic cells (DCs) results in protective immunity and rejection of established tumors in various human malignancies. The purpose of this study is to determine whether DCs are gener...