Jeanne Adiwinata Pawitan
Jeanne Adiwinata Pawitan
The hallmark of Parkinson's disease is on-going degeneration of dopaminergic neurons in the substantia nigra, which may be due to various etiologies. Various approaches to alleviate symptoms are available, such as life-long pharmacological ...
Induced pluripotent stem cells and personalized medicine: current progress and future perspectives [0.03%]
诱导多能干细胞与个性化医疗：进展与展望
Yong Soon Chun,Kyunghee Byun,Bonghee Lee
Yong Soon Chun
Generation of induced pluripotent stem cells (iPSCs) has revolutionized the field of regenerative medicine by providing researchers with a unique tool to derive disease-specific stem cells for study. iPSCs can self-renew and can differentia...
Bilateral variations of the head of the digastric muscle in Korean: a case report [0.03%]
韩国二腹肌前 belly 双侧变异一例报告
Dong-Soo Kyung,Jae-Ho Lee,Yong-Pil Lee et al.
Dong-Soo Kyung et al.
The digastric muscle, as the landmark in head and neck surgery, has two bellies, of which various variations have been reported. In the submental region of a 72-year-old Korean male cadaver, bilateral variations were found in the anterior b...
Song Eun Lee,Chaeyong Jung,Kyu Youn Ahn et al.
Song Eun Lee et al.
Anatomical variations of the biceps brachii have been described by various authors, but the occurrence of bilateral asymmetric supernumerary heads is rare and has not been reported. We found three accessory heads of the biceps brachii muscl...
Co-localization of activating transcription factor 3 and phosphorylated c-Jun in axotomized facial motoneurons [0.03%]
轴突切断的面运动神经元中活化转录因子3和磷酸化c-Jun的共定位
Byung Gu Park,Jin Sook Lee,Ji Yong Lee et al.
Byung Gu Park et al.
Activating transcription factor 3 (ATF3) and c-Jun play key roles in either cell death or cell survival, depending on the cellular background. To evaluate the functional significance of ATF3/c-Jun in the peripheral nervous system, we examin...
The high dosage of earthworm (Eisenia andrei) extract decreases cell proliferation and neuroblast differentiation in the mouse hippocampal dentate gyrus [0.03%]
高剂量的异尖尾兽盾铃姜根茎提取物可降低小鼠海马齿状回区室细胞增殖和神经元分化比例
Bing Chun Yan,Ki-Yeon Yoo,Joon Ha Park et al.
Bing Chun Yan et al.
Earthworm extract has shown anticancer characteristics. In the present study, we examined the effect of chronic treatment with a high dose of earthworm (Eisenia andrei) extract (EE) on cell proliferation and neuroblast differentiation in th...
Modulation by the GABA(B) receptor siRNA of ethanol-mediated PKA-α, CaMKII, and p-CREB intracellular signaling in prenatal rat hippocampal neurons [0.03%]
GABA(B)受体siRNA对妊娠大鼠海马神经元乙醇介导的PKA-α、CaMKII和p-CREB细胞内信号转导的调节作用研究
Hae Young Lee,Byoung-Chul Yang,Eun-Shil Lee et al.
Hae Young Lee et al.
Fetal alcohol syndrome (FAS) is a developmental neuropathology resulting from in utero exposure to ethanol; many of ethanol's effects are likely to be mediated by the neurotransmitter γ-aminobutyric acid (GABA). We studied modulation of th...
Vitamin D3 regulates cell viability in gastric cancer and cholangiocarcinoma [0.03%]
维生素D3对胃癌和胆管癌细胞活力的调控作用
Sungmin Baek,Young-Suk Lee,Hye-Eun Shim et al.
Sungmin Baek et al.
A low serum level of vitamin D has been associated with an increased incidence of gastrointestinal tract cancers. However, the effects of vitamin D3 have not been investigated in gastric cancer and cholangiocarcinoma. In the present study, ...
Resveratrol activates AMPK and suppresses LPS-induced NF-κB-dependent COX-2 activation in RAW 264.7 macrophage cells [0.03%]
白藜틴通過活化AMPK來抑制LPS誘導的NF-κB依賴性RAW 264.7巨噬細胞COX-2活化作用
Chin-Ok Yi,Byeong Tak Jeon,Hyun Joo Shin et al.
Chin-Ok Yi et al.
AMP-activated protein kinase (AMPK), an enzyme involved in energy homeostasis, regulates inflammatory responses, but its precise mechanisms are not fully understood. Recent evidence has shown that resveratrol (RES), an AMPK activator, reduc...
Intra-renal slow cell-cycle cells contribute to the restoration of kidney tubules injured by ischemia/reperfusion [0.03%]
缺血/再灌注损伤后肾小管修复过程中缓增细胞的作用
Jinu Kim,Jee In Kim,Yeon Kyung Na et al.
Jinu Kim et al.
Renal epithelial cells damaged by ischemia/reperfusion (I/R) can be restored by timely and appropriate treatment. Recent studies have reported that intra renal adult kidney stem cells contribute to the restoration of tubules damaged by I/R....