A case of allopurinol-induced fixed drug eruption confirmed with a lymphocyte transformation test [0.03%]
一项用淋巴细胞转化试验确证的别嘌醇固定型药物反应病例报告
Min-Hye Kim,Eun-Jin Shim,Jae-Woo Jung et al.
Min-Hye Kim et al.
Allopurinol is one of the causative drugs that induce fixed drug eruption (FDE). The lymphocyte transformation test (LTT) is a safe and reliable diagnostic procedure for drug allergy, but is reported to be rarely positive in patients with F...
Joo-Hee Kim,Hyun Jung Jin,Young-Hee Nam et al.
Joo-Hee Kim et al.
Allergic bronchopulmonary aspergillosis (ABPA) is a complex disease, triggered by a hypersensitivity reaction to the allergen Aspergillus fumigatus. This disease occurs frequently in patients with cystic fibrosis and severe asthma in Wester...
TLR4, 5, and 9 Agonists Inhibit Murine Airway Invariant Natural Killer T Cells in an IL-12-Dependent Manner [0.03%]
TLR4、5和9的激动剂通过IL-12依赖的方式抑制小鼠气道 invariant NKT细胞
Jae-Uoong Shim,Joon-Haeng Rhee,Young-Il Koh
Jae-Uoong Shim
Purpose: Invariant natural killer T (iNKT) cells may play an important role in the pathogenesis of asthma in mice and humans. Thus, an agent that modulates the function of iNKT cells may have therapeutic potential to cont...
Evaluation of atorvastatin for the treatment of patients with asthma: a double-blind randomized clinical trial [0.03%]
阿托伐他汀治疗哮喘的疗效评估:一项双盲随机临床试验
Abdollatif Moini,Ghasem Azimi,Abdolhay Farivar
Abdollatif Moini
Purpose: Statins are known as cholesterol-lowering agents, but have been suggested for the treatment of asthma because of their anti-inflammatory effects. In this study, the potential therapeutic effects of atorvastatin w...
Clinical Features and the Diagnostic Value of Component Allergen-Specific IgE in Hymenoptera Venom Allergy [0.03%]
黄蜂毒过敏的临床特点及组分特异性IgE诊断价值分析
Yoo Seob Shin,Jing Nan Liu,Gyu-Young Hur et al.
Yoo Seob Shin et al.
Purpose: Although patient history is vital for the diagnosis of hymenoptera venom allergy, specific IgE detection is also important to identify the culprit insect and monitor the effect of immunotherapy. We evaluated the ...
Increased Prevalence of H1N1-Induced Severe Lower Respiratory Tract Diseases in Children With Atopic Sensitization [0.03%]
I型过敏反应儿童中由H1N1病毒引起的严重下呼吸道疾病患病率增加
Yun-Ji Kim,Seung-Lok Ryu,Sun-Hee Jung et al.
Yun-Ji Kim et al.
Purpose: Viral infection is the most common aggravating factor for childhood asthma. Asthma may be a risk factor for severe respiratory symptoms in children with lower respiratory tract infections of viral etiology. Influ...
Eui-Kyung Hwang,Hyun Jung Jin,Young-Hee Nam et al.
Eui-Kyung Hwang et al.
Purpose: To evaluate asthma control in elderly individuals and identify the factors that predict poor control. Methods: A retrospective...
Myung Hyun Sohn,Kyu-Earn Kim
Myung Hyun Sohn
The cockroach represents one of the most common sources of indoor allergens worldwide, and 40%-60% of patients with asthma in urban and inner-city areas possess IgE antibodies to cockroach allergens. In Korean homes, four cockroach species ...
Enrique Gómez,Maria Jose Torres,Cristobalina Mayorga et al.
Enrique Gómez et al.
Hypersensitivity drug reactions (HDR) consist of an individual abnormal response with the involvement of the immunological system. In addition to specific immunological mechanisms where specific antibodies or sensitised T cells participate,...