Role of breast regression protein-39/YKL-40 in asthma and allergic responses [0.03%]
乳腺回退蛋白39/YKL-40在哮喘和过敏反应中的作用
Chun Geun Lee,Jack A Elias
Chun Geun Lee
BRP-39 and its human homolog YKL-40 have been regarded as a prototype of chitinase-like proteins (CLP) in mammals. Exaggerated levels of YKL-40 protein and/or mRNA have been noted in a number of diseases characterized by inflammation, tissu...
Naomi Kondo,Eiko Matsui,Akane Nishimura et al.
Naomi Kondo et al.
Allergic diseases such as bronchial asthma and atopic dermatitis develop by a combination of genetic and environmental factors. Several candidate causative genes of asthma and atopy have been reported as the genetic factors. The clinical fe...
Paul C Potter
Paul C Potter
The diagnosis and management of asthma in young children is difficult, since there are many different wheezy phenotypes with varying underlying aetiologies and outcomes. This review discusses the different approaches to managing young child...
Joo-Hee Kim,Gil-Soon Choi,Young-Min Ye et al.
Joo-Hee Kim et al.
Hyaluronidase is a goat testicular protein that hydrolyzes hyaluronic acid, a structural component of the intercellular matrix. It is commonly used as a spreading factor to improve the diffusion of drugs, including local anesthetics and che...
Occupational asthma caused by inhalation of bovine serum albumin powder [0.03%]
牛血清白蛋白粉尘吸人所致职业性哮喘病例报告
Gil-Soon Choi,Joo-Hee Kim,Haet-Nim Lee et al.
Gil-Soon Choi et al.
Bovine serum albumin (BSA), which is present in bovine plasma, is one of the major allergens affecting patients with food allergies induced by milk and meat. It is also commonly used in research laboratories. Although some reports have docu...
Etiology of hemoptysis in children: a single institutional series of 40 cases [0.03%]
儿童咯血病因分析：单中心40例报告
Jaehoon Sim,Hyeyoung Kim,Hyeonyoung Lee et al.
Jaehoon Sim et al.
Purpose: The aim of this study was to determine the causes of hemoptysis in a pediatric age group. Methods: We conducted a retrospectiv...
No evidence of association between interleukin-13 gene polymorphism in aspirin intolerant chronic urticaria [0.03%]
未发现白三烯基因多态性与阿司匹林不耐受慢性荨麻疹相关联的证据
Nami Shrestha Palikhe,Seung-Hyun Kim,Gil-Soon Choi et al.
Nami Shrestha Palikhe et al.
Aspirin-intolerant chronic urticaria (AICU) is a common condition among the chronic urticaria population, but the genetic mechanism is not yet understood. In this study, the genotypes and haplotypes of three interleukin (IL)-13 polymorphism...
Association analysis of peroxisome proliferator-activated receptors gamma gene polymorphisms with asprin hypersensitivity in asthmatics [0.03%]
哮喘患者过氧化物酶体增殖激活受体γ基因多态性与阿司匹林敏感性的关联分析
Sun-Hee Oh,Se-Min Park,Jong-Sook Park et al.
Sun-Hee Oh et al.
Purpose: Peroxisome proliferator-activated receptors (PPARs) are transcriptional factors activated by ligands of the nuclear hormone receptor superfamily. The activation of PPARgamma regulates inflammation by downregulati...
Julie Wang,Hugh A Sampson
Julie Wang
Food allergies are adverse immune reactions to food proteins that affect up to 6% of children and 3-4% of adults. A wide range of symptoms can occur depending on whether IgE or non-IgE mediated mechanism are involved. Many factors influence...
Yoo Seob Shin,Katsuyuki Takeda,Erwin W Gelfand
Yoo Seob Shin
Asthma is a complex syndrome with many clinical phenotypes in children and adults. Despite the rapidly increasing prevalence, clinical investigation and epidemiological studies of asthma, the successful introduction of new drugs has been li...