Design and Evaluation of Voriconazole Eye Drops for the Treatment of Fungal Keratitis [0.03%]
伏立康唑滴眼液的制备及其治疗真菌性角膜炎的研究
Sakshi Malhotra,Anubha Khare,Kanchan Grover et al.
Sakshi Malhotra et al.
Voriconazole is a novel antifungal agent with excellent broad spectrum activity commercially available for oral and intravenous administration. The purpose of this study was to prepare ophthalmic formulation of hydroxypropyl beta cyclodextr...
Serratiopeptidase Niosomal Gel with Potential in Topical Delivery [0.03%]
具有局部给药潜力的Serratiopeptidase尼奥索姆凝胶
Ujwala A Shinde,Shivkumar S Kanojiya
Ujwala A Shinde
The objective of present study was to develop nonionic surfactant vesicles of proteolytic enzyme serratiopeptidase (SRP) by adapting reverse phase evaporation (REV) technique and to evaluate the viability of SRP niosomal gel in treating the...
Arun Verma,Nitin Kumar,Rishabha Malviya et al.
Arun Verma et al.
This paper deals with various aspects of oral insulin delivery system. Insulin is used for the treatment of diabetes mellitus, which is characterized by the elevated glucose level (above the normal range) in the blood stream, that is, hyper...
Onkar Singh,Tarun Garg,Goutam Rath et al.
Onkar Singh et al.
Approximately 34 million people were living with human immunodeficiency virus (HIV-1) at the end of 2011. From the last two decades, researchers are actively involved in the development of an effective HIV-1 treatment, but the results inten...
Development and Evaluation of Novel Self-Nanoemulsifying Drug Delivery Systems Based on a Homolipid from Capra hircus and Its Admixtures with Melon Oil for the Delivery of Indomethacin [0.03%]
基于山羊同源脂质及其与黄瓜油混合物开发新型自纳米乳化药物传递系统递送吲哚美辛及评价
Nicholas C Obitte,Kenneth C Ofokansi,Franklin C Kenechukwu
Nicholas C Obitte
In this study, goat fat (Capra hircus) and melon oil were extracted and used to formulate self-nanoemulsifying drug delivery systems (SNEDDS) based on either goat fat alone or its admixture with melon oil by employing escalating ratios of o...
Combinative Particle Size Reduction Technologies for the Production of Drug Nanocrystals [0.03%]
用于药物纳米晶体生产的组合粒径减小技术
Jaime Salazar,Rainer H Müller,Jan P Möschwitzer
Jaime Salazar
Nanosizing is a suitable method to enhance the dissolution rate and therefore the bioavailability of poorly soluble drugs. The success of the particle size reduction processes depends on critical factors such as the employed technology, equ...
Solubility Enhancement of Budesonide and Statistical Optimization of Coating Variables for Targeted Drug Delivery [0.03%]
布地奈德溶解度增强及靶向药物递送的包衣变量统计优化
Himanshu Bhatt,Bhargavi Naik,Abhay Dharamsi
Himanshu Bhatt
The purpose of the research was to present Budesonide (BUD) as a novel formulation showing improved aqueous solubility, which may decrease variability in C max and T max found in inflammatory bowel disease (IBD) patients, and drug targe...
Recently Investigated Natural Gums and Mucilages as Pharmaceutical Excipients: An Overview [0.03%]
近期作为药用辅料的天然胶和粘胶研究概述
Pritam Dinesh Choudhary,Harshal Ashok Pawar
Pritam Dinesh Choudhary
Due to advances in drug delivery technology, currently, excipients are included in novel dosage forms to fulfil specific functions and in some cases they directly or indirectly influence the extent and/or rate of drug release and drug absor...
Harkiran Kaur,Gurpreet Kaur
Harkiran Kaur
Polyphenols constitute a family of natural substances distributed widely in plant kingdom. These are produced as secondary metabolites by plants and so far 8000 representatives of this family have been identified. Recently, there is an incr...
Formulation and Characterization of Solid Dispersion Prepared by Hot Melt Mixing: A Fast Screening Approach for Polymer Selection [0.03%]
一种快速筛选聚合物的热熔融混合固体分散体制备及表征方法研究
Arno A Enose,Priya K Dasan,H Sivaramakrishnan et al.
Arno A Enose et al.
Solid dispersion is molecular dispersion of drug in a polymer matrix which leads to improved solubility and hence better bioavailability. Solvent evaporation technique was employed to prepare films of different combinations of polymers, pla...