Antibacterial Derivatives of Ciprofloxacin to Inhibit Growth of Necrotizing Fasciitis Associated Penicillin Resistant Escherichia coli [0.03%]
抑制引起坏死性筋膜炎的青霉素耐药大肠杆菌生长的环丙沙星抗菌衍生物
Ronald Bartzatt,Suat L G Cirillo,Jeffrey D Cirillo
Ronald Bartzatt
Escherichia coli (E. coli) is associated with necrotizing fasciitis (type I) and can induce enough damage to tissue causing hypoxia. Three ester derivatives of the broad-spectrum antibiotic ciprofloxacin were placed into bacteria culture si...
Monica Rao,Girish Sukre,Sheetal Aghav et al.
Monica Rao et al.
The purpose of the present study was to develop and optimize the emulgel system for MTZ (Metronidazole), a poorly water soluble drug. The pseudoternary phase diagrams were developed for various microemulsion formulations composed of Capmul ...
Determination of Zalcitabine in Medicaments by Differential Pulse Voltammetry [0.03%]
差分脉冲伏安法测定药物中的拉米夫定
Katia Christina Leandro,Josino Costa Moreira,Pércio Augusto Mardini Farias
Katia Christina Leandro
The zalcitabine (ddC) has been extensively used in the treatment of HIV patients due to its antiretroviral activity. The quality control of this active principle in medications is of outstanding importance to public health. The principal ob...
Quantification of Lumefantrine in Human Plasma Using LC-MS/MS and Its Application to a Bioequivalence Study [0.03%]
高效液相色谱-质谱联用测定人血浆中 lumefantrine 并用于生物等效性研究
Satish G Pingale,Kiran V Mangaonkar
Satish G Pingale
An analytical method based on protein precipitation has been developed and validated for analysis of lumefantrine in human plasma. Artesunate was used as an internal standard for lumefantrine. Inertsil ODS column provided chromatographic se...
Preparation and Evaluation of Valsartan Liquid Filling Formulations for Soft Gels [0.03%]
缬沙坦液体填充液体制备及其评价研究
Jyothi Sanaboina,K M Maheswari,Seetha Sunkara et al.
Jyothi Sanaboina et al.
The present investigation includes the preparation of liquid filling formulations for soft gels using an antihypertensive drug, valsartan (VAL), in order to improve its dissolution properties and thereby its bioavailability. Formulations we...
Simultaneous Determination of Clidinium Bromide and Chlordiazepoxide in Combined Dosage Forms by High-Performance Liquid Chromatography [0.03%]
高效液相色谱法同时测定复方制剂中的氯二甲苯菊酯和氯化铵溴化物
Safwan Ashour,Nuha Kattan
Safwan Ashour
A sensitive and precise RP-HPLC method has been developed for the simultaneous estimation of clidinium bromide (CDB) and chlordiazepoxide (CDZ) in pure and pharmaceutical formulations. The separation was achieved on a Nucleodur C8 (250 × 4...
Optimization of Carboxymethyl-Xyloglucan-Based Tramadol Matrix Tablets Using Simplex Centroid Mixture Design [0.03%]
基于羧甲基半乳聚糖的 tramadol 矩阵片剂制备工艺优化研究
Ashwini R Madgulkar,Mangesh R Bhalekar,Rahul R Padalkar et al.
Ashwini R Madgulkar et al.
The aim was to determine the release-modifying effect of carboxymethyl xyloglucan for oral drug delivery. Sustained release matrix tablets of tramadol HCl were prepared by wet granulation method using carboxymethyl xyloglucan as matrix form...
Innovative Approach for Interstitial Cystitis: Vaginal Pessaries Loaded Diazepam-A Preliminary Study [0.03%]
一种治疗间质性膀胱炎的创新方法：载有地西泮的阴道宫内节育器-初步研究
P Capra,P Perugini,M Bleve et al.
P Capra et al.
Bladder pain is a characteristic disorder of interstitial cystitis. Diazepam is well known for its antispasmodic activity in the treatment of muscular hypertonus. The aim of this work was to develop and characterize vaginal pessaries as an ...
Mossad Gamaleddin Ahmed Elsayed,Ashraf Abdelhakim Ahmed Elkomy,Mohamed Elbadawy
Mossad Gamaleddin Ahmed Elsayed
Some pharmacodynamic effects of cefepime, a new injectable semisynthetic cephalosporin, were studied in laboratory animals and the following results were obtained. Cefepime maximally stimulated isolated guinea pig's ileum, rat's colon (80 ...
Health Technology Assessment Fireside: Antibiotic Prophylaxis and Dental Treatment in Canada [0.03%]
加拿大的口腔治疗与抗生素预防性用药健康技术评估茶话会
Mario A Brondani
Mario A Brondani
Objectives. This paper discusses the controversies surrounding the antibiotic prophylaxis preceding dental interventions within the following research question: how effective is dental antibiotic prophylaxis in preventing comorbidity and co...