Gualtiero Palareti
Gualtiero Palareti
Venous thromboembolism (VTE) that includes deep vein thrombosis and/or pulmonary embolism is a frequent, severe, and potentially lethal disease. After a first episode, VTE has a strong tendency to recur. While VTE is an acute disease, it ma...
Sanjeev Kumar Mahto,Janna Tenenbaum-Katan,Josué Sznitman
Sanjeev Kumar Mahto
Our current understanding of respiratory physiology and pathophysiological mechanisms of lung diseases is often limited by challenges in developing in vitro models faithful to the respiratory environment, both in cellular structure and phys...
Hemolytic uremic syndrome: late renal injury and changing incidence-a single centre experience in Canada [0.03%]
溶血性尿毒综合征：晚期肾损伤及发病率的变化——加拿大单中心经验
Pierre Robitaille,Marie-José Clermont,Aïcha Mérouani et al.
Pierre Robitaille et al.
Aims. To assess trends in the incidence of pediatric diarrhea-associated hemolytic uremic syndrome (D(+) HUS) and document long-term renal sequelae. Methods. We conducted a retrospective cohort study of children with D(+) HUS admitted to a ...
Graciela Krikun
Graciela Krikun
Tissue factor (TF), is a cellular receptor that binds the factor VII/VIIa to initiate the blood coagulation cascade. In addition to its role as the initiator of the hemostatic cascade, TF is known to be involved in angiogenesis via intracel...
Kinome profiling [0.03%]
激酶组筛选
Maikel P Peppelenbosch
Maikel P Peppelenbosch
The use of arrays in genomics has led to a fast and reliable way to screen the transcriptome of an organism. It can be automated and analysis tools have become available and hence the technique has become widely used within the past few yea...
Diabetes technology: markers, monitoring, assessment, and control of blood glucose fluctuations in diabetes [0.03%]
糖尿病技术：糖尿病血糖波动的标志、监测、评估和控制
Boris P Kovatchev
Boris P Kovatchev
People with diabetes face a life-long optimization problem: to maintain strict glycemic control without increasing their risk for hypoglycemia. Since the discovery of insulin in 1921, the external regulation of diabetes by engineering means...
Chronic heart failure: we are fighting the battle, but are we winning the war? [0.03%]
慢性心力衰竭：我们在努力作战，但战争胜利了吗？
John J Atherton
John J Atherton
Heart failure represents an end-stage phenotype of a number of cardiovascular diseases and is generally associated with a poor prognosis. A number of organized battles fought over the last two to three decades have resulted in considerable ...
Robert C Barber
Robert C Barber
Alzheimer's disease is a progressive, neurodegenerative disease that represents a growing global health crisis. Two major forms of the disease exist: early onset (familial) and late onset (sporadic). Early onset Alzheimer's is rare, account...
The Need for Development of New HIV-1 Reverse Transcriptase and Integrase Inhibitors in the Aftermath of Antiviral Drug Resistance [0.03%]
抗病毒药物耐药后的HIV-1逆转录酶和整合酶抑制剂的发展需求分析
Mark A Wainberg
Mark A Wainberg
The use of highly active antiretroviral therapy (HAART) involves combinations of drugs to achieve maximal virological response and reduce the potential for the emergence of antiviral resistance. There are two broad classes of reverse transc...
Montasser Nadeem,Basil Elnazir,Peter Greally
Montasser Nadeem
Congenital Pulmonary Malformations (CPMs) are a group of rare lung abnormalities affecting the airways, parenchyma, and vasculature. They represent a spectrum of abnormal development rather than discrete pathological entities. They are caus...