Anti-interleukin-6 receptor antibody therapy-induced retinopathy in a patient with rheumatoid arthritis [0.03%]
风湿性关节炎患者注射抗白细胞介素6受体抗体诱导的视网膜病变
Asumi Tada,Noriyasu Hashida,Toshio Tanaka et al.
Asumi Tada et al.
Tocilizumab, a humanized anti-human interleukin-6 (IL-6) receptor monoclonal antibody, is beneficial for treating autoimmune conditions such as rheumatoid arthritis (RA). The most common adverse event is upper respiratory tract infection; o...
Alfredo Sánchez-Cruz,Sylmarie Marrero,José Betancourt et al.
Alfredo Sánchez-Cruz et al.
Cocaine abuse is relatively common in our society. To enhance profitability and acceptability of the product, it is not uncommon for illicit drugs to undergo several processes. The Drug Enforcement Agency (DEA) has reported that seventy per...
A Rare Case of Kikuchi Fujimoto's Disease with Subsequent Development of Systemic Lupus Erythematosus [0.03%]
Kikuchi病1例并发系统性红斑狼疮
Yu Zuo,Michelle Foshat,You-Wen Qian et al.
Yu Zuo et al.
Kikuchi Fujimoto's disease (KFD) is a rare, immune-mediated, self-limiting disorder with unique histopathological features. KFD is usually seen in young Asian females; however, cases have been reported throughout the world and in all ethnic...
Kuljeet Bhamra,Richard Stevens
Kuljeet Bhamra
Tumour necrosis factor (TNF) is an important cytokine involved in the pathology of a number of inflammatory conditions, and thus blockade with anti-TNF therapies is becoming the cornerstone in managing such diseases. With increasing use, ev...
Diffuse Muscular Pain, Skin Tightening, and Nodular Regenerative Hyperplasia Revealing Paraneoplastic Amyopathic Dermatomyositis due to Testicular Cancer [0.03%]
肌肉弥漫性疼痛、皮肤紧绷和结节再生性增生型肌炎样血管病提示睾丸癌相关无肌炎性皮肌炎
Sarah Norrenberg,Valérie Gangji,Véronique Del Marmol et al.
Sarah Norrenberg et al.
Paraneoplastic dermatomyositis (DM) associated with testicular cancer is extremely rare. We report the case of a patient with skin tightening, polymyalgia, hypereosinophilia, and nodular regenerative hyperplasia revealing seminoma and assoc...
Efficacy and safety of rituximab in the treatment of vasculitic leg ulcers associated with hepatitis C virus infection [0.03%]
利妥昔单抗治疗丙型肝炎病毒感染相关的血管炎性腿溃疡的疗效和安全性
Fabio Bonilla-Abadía,Andrés F Echeverri,Jorge H Izquierdo et al.
Fabio Bonilla-Abadía et al.
Vasculitic leg ulcers are a cutaneous manifestation of hepatitis C virus (HCV) infection often associated with cryoglobulinemia. Their treatment is difficult and is based on steroids and immunosuppressive drugs with an erratic response and ...
Acute Generalized Exanthematous Pustulosis due to Tocilizumab in a Rheumatoid Arthritis Patient [0.03%]
风湿病患者使用托珠单抗诱发的急性泛发性发疹性脓疱病(AEP)
J H Izquierdo,F Bonilla-Abadía,C D Ochoa et al.
J H Izquierdo et al.
We report a female patient with rheumatoid arthritis which was refractory to methotrexate, leflunomide, and anti-TNF therapy. She was treated with anti-IL-6 tocilizumab (TCZ), with an early appearance of sterile pustules on erythematous swo...
Nathan D Oliver,Auleen Millar,Adrian Pendleton
Nathan D Oliver
Introduction. Whilst there are reports of viral myopathies affecting children and the immunocompromised, infective myositis is a relatively rare inflammatory myopathy in adults. The clinical spectrum can range from benign myalgias to more s...
Severe eosinophilic syndrome associated with the use of probiotic supplements: a new entity? [0.03%]
与使用益生菌补充剂相关的严重嗜酸细胞性综合征：一种新的疾病实体？
Fabian A Mendoza,Shivani Purohit,Lawrence Kenyon et al.
Fabian A Mendoza et al.
Severe eosinophilic syndromes related to the administration or use of unsuspected immunogenic substances have been described previously. Many of these diseases presented initially as clusters or isolated cases. The spanish toxic oil syndrom...
Psoriatic Arthritis during Treatment with Bevacizumab for Anaplastic Oligodendroglioma [0.03%]
贝伐单抗治疗间变性 oliogodendroglioma患者的银屑病关节炎病例报告
D Graceffa,E Maiani,A Pace et al.
D Graceffa et al.
Bevacizumab is a recombinant humanised monoclonal antibody directed against the vascular endothelial growth factor (VEGF). The drug, alone or in combination with other anticancer agents, has been shown to be effective against several types ...