Cyanamide potentiates the ethanol-induced impairment of receptor-mediated endocytosis in a recombinant hepatic cell line expressing alcohol dehydrogenase activity [0.03%]
氰胺增强乙醇对表达酒精脱氢酶活性的重组肝细胞系受体介导的内吞作用的影响
Dahn L Clemens,Dean J Tuma,Carol A Casey
Dahn L Clemens
Ethanol administration has been shown to alter receptor-mediated endocytosis in the liver. We have developed a recombinant hepatic cell line stably transfected with murine alcohol dehydrogenase cDNA to serve as an in vitro model to investig...
A multimodal approach to the management of neuroendocrine tumour liver metastases [0.03%]
神经内分泌肿瘤肝转移的多模式处理方法
Ron Basuroy,Rajaventhan Srirajaskanthan,John K Ramage
Ron Basuroy
Neuroendocrine tumours (NETs) are often indolent malignancies that commonly present with metastatic disease in the liver. Surgical, locoregional, and systemic treatment modalities are reviewed. A multidisciplinary approach to patient care i...
Dan Granberg,Wouter de Herder,Dermot O&#x;Toole et al.
Dan Granberg et al.
Shashi Bala,Gyongyi Szabo
Shashi Bala
Alcoholic liver disease (ALD) is a major global health problem. Chronic alcohol use results in inflammation and fatty liver, and in some cases, it leads to fibrosis and cirrhosis or hepatocellular carcinoma. Increased proinflammatory cytoki...
Potential Antioxidant Role of Tridham in Managing Oxidative Stress against Aflatoxin-B(1)-Induced Experimental Hepatocellular Carcinoma [0.03%]
天然药物Tridham的抗氧化作用及其对黄曲霉素B1诱导肝细胞癌小鼠氧化应激的影响研究
Vijaya Ravinayagam,Ravindran Jaganathan,Sachdanandam Panchanadham et al.
Vijaya Ravinayagam et al.
Hepatocellular carcinoma (HCC) is one of the most fatal cancers due to delayed diagnosis and lack of effective treatment options. Significant exposure to Aflatoxin B(1) (AFB(1)), a potent hepatotoxic and hepatocarcinogenic mycotoxin, plays ...
Flow injection/sequential injection analysis systems: potential use as tools for rapid liver diseases biomarker study [0.03%]
流动注射/顺序注射分析系统在快速肝脏疾病生物标志物研究中的潜在应用价值
Supaporn Kradtap Hartwell
Supaporn Kradtap Hartwell
Flow injection/sequential injection analysis (FIA/SIA) systems are suitable for carrying out automatic wet chemical/biochemical reactions with reduced volume and time consumption. Various parts of the system such as pump, valve, and reactor...
Treatment of liver metastases in patients with neuroendocrine tumors of gastroesophageal and pancreatic origin [0.03%]
胃食管和胰腺神经内分泌肿瘤肝转移的治疗
Ping Gu,Jennifer Wu,Elliot Newman et al.
Ping Gu et al.
Well-to-moderately differentiated neuroendocrine tumors of gastroesophageal and pancreatic origin (GEP-NETs) with liver metastasis are a heterogeneous group of malignancies for which a range of therapeutic options have been employed. Surgic...
Lipid droplet accumulation and impaired fat efflux in polarized hepatic cells: consequences of ethanol metabolism [0.03%]
乙醇代谢对极化肝细胞内脂滴聚集和脂肪外流受损的影响
Benita L McVicker,Karuna Rasineni,Dean J Tuma et al.
Benita L McVicker et al.
Steatosis, an early manifestation in alcoholic liver disease, is associated with the accumulation of hepatocellular lipid droplets (LDs). However, the role ethanol metabolism has in LD formation and turnover remains undefined. Here, we asse...
HIV-Antiretroviral Therapy Induced Liver, Gastrointestinal, and Pancreatic Injury [0.03%]
HIV抗逆转录病毒治疗所致的肝脏、胃肠道和胰腺损伤
Manuela G Neuman,Michelle Schneider,Radu M Nanau et al.
Manuela G Neuman et al.
The present paper describes possible connections between antiretroviral therapies (ARTs) used to treat human immunodeficiency virus (HIV) infection and adverse drug reactions (ADRs) encountered predominantly in the liver, including hypersen...
Kara Rye,Robert Scott,Gerri Mortimore et al.
Kara Rye et al.
Current guidelines recommend that all cirrhotic patients should undergo screening endoscopy at diagnosis to identify patients with varices at high risk of bleeding who will benefit from primary prophylaxis. This approach places a heavy burd...