The Link between Hypersensitivity Syndrome Reaction Development and Human Herpes Virus-6 Reactivation [0.03%]
人类疱疹病毒6型再激活与超敏综合征反应发生之间的关联性研究
Joshua C Pritchett,Radu M Nanau,Manuela G Neuman
Joshua C Pritchett
Background. There are challenges in the clinical diagnosis of drug-induced injury and in obtaining information on the reactivation of human herpes viruses (HHV) during idiosyncratic adverse drug reactions. Objectives. (i) To develop a unifi...
Tara Behne,M Sitki Copur
Tara Behne
The hepatocellular carcinoma (HCC) is one of the most common malignant tumors and carries a poor survival rate. The management of patients at risk for developing HCC remains challenging. Increased understanding of cancer biology and technol...
Kazuto Tajiri,Yukihiro Shimizu
Kazuto Tajiri
Nonalcoholic fatty liver disease (NAFLD) is the most frequent chronic liver disease and shows various inflammatory changes in the liver. Among those inflammatory cells, natural killer T (NKT) cells are found to have a critical role during t...
Yen-I Chen,Peter Ghali
Yen-I Chen
Variceal hemorrhage is one of the major complications of liver cirrhosis associated with significant mortality and morbidity. Its management has evolved over the past decade and has substantially reduced the rate of first and recurrent blee...
Jayashree Bagchi Chakraborty,Fiona Oakley,Meagan J Walsh
Jayashree Bagchi Chakraborty
Liver fibrosis and cirrhosis are a major cause of morbidity and mortality worldwide. Development of the fibrotic scar is an outcome of chronic liver diseases of varying aetiologies including alcoholic liver disease (ALD) nonalcoholic liver ...
Nutrition and nonalcoholic Fatty liver disease: the significance of cholesterol [0.03%]
营养与非酒精性脂肪肝病：胆固醇的意义
Munechika Enjoji,Kenichiro Yasutake,Motoyuki Kohjima et al.
Munechika Enjoji et al.
Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver disease that ranges in severity from simple steatosis to cirrhosis. NAFLD is considered to be associated with hepatic metabolic disorders, resulting in overaccumulation of f...
Natalia Osna,Kusum Kharbanda,Laura Schrum et al.
Natalia Osna et al.
Helieh S Oz,Karin H Westlund
Helieh S Oz
Babesiosis, a common disease of animals, can infect humans via vector "tick bite", particularly in endemic areas. The recent reports of fatal cases in Hepatitis C and postliver transplant patients resulting from transfusion of contaminated ...
Paraoxonase activity and expression is modulated by therapeutics in experimental rat nonalcoholic Fatty liver disease [0.03%]
药物可调节实验性大鼠非酒精性脂肪肝病中的卵磷脂胆固醇酰基转移酶活性及表达量
O Hussein,J Zidan,K Abu Jabal et al.
O Hussein et al.
Objective. The objective of the present study is to investigate the effect of rosiglitazone, metformin, ezetimibe, and valsartan (alone or in combinations) on paraoxonase (PON) activity and PON-mRNA expression in nonalcoholic fatty liver di...
Markers of inflammation and fibrosis in alcoholic hepatitis and viral hepatitis C [0.03%]
酒精性肝炎和C型肝炎患者炎症及纤维化指标的差异分析
Manuela G Neuman,Hemda Schmilovitz-Weiss,Nir Hilzenrat et al.
Manuela G Neuman et al.
High levels of profibrinogenic cytokine transforming factor beta (TGF-β), metalloprotease (MMP2), and tissue inhibitor of matrix metalloprotease 1 (TIMP1) contribute to fibrogenesis in hepatitis C virus (HCV) infection and in alcohol-induc...