Said A Al-Busafi,Julia McNabb-Baltar,Amanda Farag et al.
Said A Al-Busafi et al.
The portal hypertension is responsible for many of the manifestations of liver cirrhosis. Some of these complications are the direct consequences of portal hypertension, such as gastrointestinal bleeding from ruptured gastroesophageal varic...
The utility of scoring systems in predicting early and late mortality in alcoholic hepatitis: whose score is it anyway? [0.03%]
酒精性肝炎早期和晚期死亡预测评分系统的实用性的研究：究竟是谁的评分系统呢？
Naaventhan Palaniyappan,Venkataraman Subramanian,Vidyasagar Ramappa et al.
Naaventhan Palaniyappan et al.
Background. Alcoholic hepatitis (AH) is a distinct clinical entity in the spectrum of alcoholic liver disease with a high short-term mortality. Several scoring systems are being used to assess the severity of AH but the ability of these sco...
Watch the GAP: Emerging Roles for IQ Motif-Containing GTPase-Activating Proteins IQGAPs in Hepatocellular Carcinoma [0.03%]
IQ motif含GTP酶激活蛋白(IQGs)在肝细胞癌中的作用不容忽视：IQGs在肝细胞癌中扮演新兴角色
Valentina A Schmidt
Valentina A Schmidt
IQ motif-containing GTPase-activating proteins IQGAP1 and IQGAP2 are highly homologous multidomain scaffolding proteins. Their major function consists of integration of Rho GTPase and Ca(2+)/calmodulin signals with cell adhesive and cytoske...
A Complex Interplay between Wnt/β-Catenin Signalling and the Cell Cycle in the Adult Liver [0.03%]
成人肝脏中Wnt/β-catenin信号与细胞周期的相互作用
Angélique Gougelet,Sabine Colnot
Angélique Gougelet
Canonical Wnt signalling, governed by its effector β-catenin, is known for a long time as playing an important role in development, tissue homeostasis, and cancer. In the liver, it was unravelled as both an oncogenic pathway involved in a ...
Motoko Sasaki,Yasuni Nakanuma
Motoko Sasaki
Hepatocellular adenoma (HCA) is generally a benign hepatocellular tumor arising in a nonfibrotic/cirrhotic liver, and recently four major subgroups were identified based on genotype and phenotype classification from Europe. HCA is rare in A...
Min Cong,Keiko Iwaisako,Chunyan Jiang et al.
Min Cong et al.
Liver fibrosis is the result of the entire organism responding to a chronic injury. Every cell type in the liver contributes to the fibrosis. This paper first discusses key intracellular signaling pathways that are induced during liver fibr...
David H Van Thiel,Magdalena George,Christopher M Moore
David H Van Thiel
Systemic fungal infections typically occur in individuals who are seriously ill with recognized risk factors such as those frequently found in transplant recipients. Unfortunately, they are often diagnosed late, when the efficacy of the ava...
Milan Criteria and UCSF Criteria: A Preliminary Comparative Study of Liver Transplantation Outcomes in the United States [0.03%]
米兰标准与UCSF标准在美国肝脏移植结局的初步比较研究
Supriya S Patel,Amanda K Arrington,Shaun McKenzie et al.
Supriya S Patel et al.
The application of orthotopic liver transplantation (OLT) for patients with hepatocellular cancer (HCC) necessitates highly selective criteria to maximize survival and to optimize allocation of a scarce resource. The objective of this study...
Nonalcoholic Fatty liver disease in chronic hepatitis B and C patients from Western Amazon [0.03%]
西亚马逊地区慢性乙肝和丙肝患者的非酒精性脂肪肝病
A C M Nascimento,D R Maia,S M Neto et al.
A C M Nascimento et al.
Nonalcoholic fatty liver disease (NAFLD) includes a wide spectrum of histological conditions, extending from simple steatosis to end-stage liver failure. The aim of this study was to examine the prevalence of NAFLD and its associations in c...
Fuad Maufa,Firas H Al-Kawas
Fuad Maufa
Acute variceal bleeding continues to be associated with significant mortality. Current standard of care combines hemodynamic stabilization, antibiotic prophylaxis, pharmacological agents, and endoscopic treatment. Rescue therapies using bal...