Etiology and management of hemorrhagic complications of portal hypertension in children [0.03%]
儿童门脉高压症出血并发症的病因及处理方法
Alejandro Costaguta,Fernando Alvarez
Alejandro Costaguta
PORTAL HYPERTENSION IN CHILDREN REPRESENTS A PARTICULAR DIAGNOSTIC AND MANAGEMENT CHALLENGE FOR SEVERAL REASONS: (1) treatment outcomes should be evaluated in relationship with a long-life expectancy, (2) pediatric patients with portal hype...
Julie Pajaud,Sandeep Kumar,Claudine Rauch et al.
Julie Pajaud et al.
Glutathione transferases (GST) are essentially known as enzymes that catalyse the conjugation of glutathione to various electrophilic compounds such as chemical carcinogens, environmental pollutants, and antitumor agents. However, this prot...
Regulation of the g1/s transition in hepatocytes: involvement of the cyclin-dependent kinase cdk1 in the DNA replication [0.03%]
肝细胞中G1/S转换的调节：周期素依赖性蛋白激酶Cdk1在DNA复制中的作用
Anne Corlu,Pascal Loyer
Anne Corlu
A singular feature of adult differentiated hepatocytes is their capacity to proliferate allowing liver regeneration. This review emphasizes the literature published over the last 20 years that established the most important pathways regulat...
Experience Since MELD Implementation: How Does the New System Deliver? [0.03%]
MELD实施以来的肝移植经验：新系统效果如何？
Markus Quante,Christoph Benckert,Armin Thelen et al.
Markus Quante et al.
Because of increasing waiting-list mortality, the MELD (Model for End-Stage Liver Disease) allocation system was implemented within most countries of the Eurotransplant area on December 16, 2006. Five years have now passed, and we review in...
Lars Ole Schwen,Tobias Preusser
Lars Ole Schwen
A proper geometric model of the vascular systems in the liver is crucial for modeling blood flow, the connection between the organ and the rest of the organism. In vivo imaging does not provide sufficient details, so an algorithmic concept ...
Garrick K Wilson,Zania Stamataki
Garrick K Wilson
The study of a virus is made possible by the availability of culture systems in which the viral lifecycle can be realized. Such systems support robust virus entry, replication, assembly, and secretion of nascent virions. Furthermore, cultur...
Recovery of the Cell Cycle Inhibition in CCl(4)-Induced Cirrhosis by the Adenosine Derivative IFC-305 [0.03%]
腺苷衍生物IFC-305可恢复四氯化碳致肝硬化肝细胞周期抑制现象
Victoria Chagoya de Sánchez,Lidia Martínez-Pérez,Rolando Hernández-Muñoz et al.
Victoria Chagoya de Sánchez et al.
Introduction. Cirrhosis is a chronic degenerative illness characterized by changes in normal liver architecture, failure of hepatic function, and impairment of proliferative activity. The aim of this study is to know how IFC-305 compound in...
Alexandra Collin de L&#x;hortet,Hélène Gilgenkrantz,Jacques-Emmanuel Guidotti
Alexandra Collin de L&#x;hortet
Unraveling the molecular clues of liver proliferation has become conceivable thanks to the model of two-third hepatectomy. The synchronicity and the well-scheduled aspect of this process allow scientists to slowly decipher this mystery. Dur...
Implications of the Use of Eukaryotic Translation Initiation Factor 5A (eIF5A) for Prognosis and Treatment of Hepatocellular Carcinoma [0.03%]
真核生物翻译起始因子5A（eIF5A）用于预测和治疗肝细胞癌的潜在影响
Felix H Shek,Sarwat Fatima,Nikki P Lee
Felix H Shek
Hepatocellular carcinoma (HCC) is a primary liver malignancy and accounts for most of the total liver cancer cases. Lack of treatment options and late diagnosis contribute to high mortality rate of HCC. In eukaryotes, translation of messeng...
How normal is the liver in which the inflammatory type hepatocellular adenoma develops? [0.03%]
炎症性肝细胞腺瘤发生的肝脏是正常的吗？
Jing Han,Marius C van den Heuvel,Hironori Kusano et al.
Jing Han et al.
The inflammatory type hepatocellular adenoma (IHCA) is a subtype of HCA which is a benign liver tumor, predominantly occurring in young women in an otherwise normal liver. IHCA contains either a mutation of gp130 or STAT3. Both mutations le...