Evaluation of sentinel node biopsy in locally advanced breast cancer patients who become clinically node-negative after neoadjuvant chemotherapy: a preliminary study [0.03%]
新辅助化疗后临床转为腋窝阴性的局部进展期乳腺癌患者行前哨淋巴结活检的可行性初步研究
Shaji Thomas,Apurva Prakash,Vinay Goyal et al.
Shaji Thomas et al.
Introduction. Controversy continues over the appropriate timing of sentinel lymph node (SLN) biopsy in locally advanced breast cancer (LABC) patients receiving neoadjuvant chemotherapy. We evaluated the feasibility and accuracy of SLN biops...
Lymphangiogenesis and Axillary Lymph Node Metastases Correlated with VEGF-C Expression in Two Immunocompetent Mouse Mammary Carcinoma Models [0.03%]
血管内皮生长因子-Ｃ表达与乳腺癌淋巴管生成和腋窝淋巴结转移的关系研究
Yuko Ito,Masa-Aki Shibata,Nabil Eid et al.
Yuko Ito et al.
Lymphangiogenesis and the expression of vascular endothelial cell growth factor C (VEGF-C) in tumors have been considered to be causally promoting lymphatic metastasis. There are only a few studies on lymphatic metastasis in immunocompetent...
Cancer multidisciplinary team meetings: evidence, challenges, and the role of clinical decision support technology [0.03%]
肿瘤多学科团队会议：证据、挑战及临床决策支持技术的作用
Vivek Patkar,Dionisio Acosta,Tim Davidson et al.
Vivek Patkar et al.
Multidisciplinary team (MDT) model in cancer care was introduced and endorsed to ensure that care delivery is consistent with the best available evidence. Over the last few years, regular MDT meetings have become a standard practice in onco...
Breast cancer preoperative staging: does contrast-enhanced magnetic resonance mammography modify surgery? [0.03%]
乳腺癌术前分期：对比磁共振断层摄影影响手术吗？
Chiara Perono Biacchiardi,Davide Brizzi,Franco Genta et al.
Chiara Perono Biacchiardi et al.
Women with newly diagnosed breast cancer may have lesions undetected by conventional imaging. Recently contrast-enhanced magnetic resonance mammography (CE-MRM) showed higher sensitivity in breast lesions detection. The present analysis was...
Redefining lumpectomy using a modification of the "sick lobe" hypothesis and ductal anatomy [0.03%]
用"病灶叶段"假设和导管解剖改良重定义保乳手术
W Dooley,J Bong,J Parker
W Dooley
Objectives. The "Sick Lobe" hypothesis states that breast cancers evolve from entire lobes or portions of lobes of the breast where initiation events have occurred early in development. The implication is that some cancers are isolated even...
Metronomic Cyclophosphamide and Methotrexate Chemotherapy Combined with 1E10 Anti-Idiotype Vaccine in Metastatic Breast Cancer [0.03%]
卡培他滨联合methotruxate化疗及1E10抗-id疫苗治疗转移性乳腺癌
Jorge L Soriano,Noyde Batista,Eduardo Santiesteban et al.
Jorge L Soriano et al.
The use of low doses of cytotoxic agents continuously for prolonged periods is an alternative for the treatment of patients with metastatic breast cancer who have developed resistance to conventional chemotherapy. The combination of metrono...
Subgross morphology, the sick lobe hypothesis, and the success of breast conservation [0.03%]
副形态学、病灶侧乳腺假说和保乳手术的成功率
Tibor Tot
Tibor Tot
Breast carcinoma has a complex subgross morphology in the majority of cases. The malignant transformation usually involves a single breast lobe and may demonstrate peripheral, segmental, or lobar growth patterns in the in situ phase. During...
Autophagy: friend or foe in breast cancer development, progression, and treatment [0.03%]
自噬在乳腺癌发生、发展及治疗中的利弊作用
Damian E Berardi,Paola B Campodónico,Maria Ines Díaz Bessone et al.
Damian E Berardi et al.
Autophagy is a catabolic process responsible for the degradation and recycling of long-lived proteins and organelles by lysosomes. This degradative pathway sustains cell survival during nutrient deprivation, but in some circumstances, autop...
Obesity is an independent predictor of poor survival in metastatic breast cancer: retrospective analysis of a patient cohort whose treatment included high-dose chemotherapy and autologous stem cell support [0.03%]
肥胖是转移性乳腺癌预后不良的独立预测因素：回顾性分析接受大剂量化疗和自体干细胞支持治疗患者的队列数据
A von Drygalski,T B Tran,K Messer et al.
A von Drygalski et al.
The purpose of the study was to identify predictors of long-term survival in metastatic breast cancer (MBC). A cohort of 96 patients, who received high-dose chemotherapy with autologous stem cell support (HD-ASCT) as part of their treatment...
Duct Excision is Still Necessary to Rule out Breast Cancer in Patients Presenting with Spontaneous Bloodstained Nipple Discharge [0.03%]
自发性血性乳头溢液患者仍需施行导管切除术以排除乳腺癌的可能性
R E Foulkes,G Heard,T Boyce et al.
R E Foulkes et al.
Introduction. Spontaneous nipple discharge is the third most common reason for presentation to a symptomatic breast clinic. Benign and malignant causes of spontaneous nipple discharge continue to be difficult to distinguish. We analyse our ...