Role of CEACAM1, ECM, and mesenchymal stem cells in an orthotopic model of human breast cancer [0.03%]
人源性乳腺癌原位移植瘤小鼠模型中CEACAM1、ECM和间充质干细胞的作用机制研究
Sridhar Samineni,Carlotta Glackin,John E Shively
Sridhar Samineni
Carcinoembryonic antigen-related cell adhesion molecule-1 (CEACAM1) is a morphogen in an in vitro model for lumen formation and plays a similar role in breast epithelial cells implanted in humanized mammary fat pads in NOD-SCID mice. Althou...
Experience of initial symptoms of breast cancer and triggers for action in ethiopia [0.03%]
埃塞俄比亚乳腺癌初期症状体验及采取行动的触发因素
Timothy D Dye,Solomon Bogale,Claire Hobden et al.
Timothy D Dye et al.
Objective. This study assessed the initial experiences, symptoms, and actions of patients in Ethiopia ultimately determined to have breast cancer. Methods. 69 participants in a comprehensive breast cancer treatment program at the main natio...
Changes in Cytokines of the Bone Microenvironment during Breast Cancer Metastasis [0.03%]
乳腺癌转移过程中骨微环境细胞因子的变化
Donna M Sosnoski,Venkatesh Krishnan,William J Kraemer et al.
Donna M Sosnoski et al.
It is commonly accepted that cancer cells interact with host cells to create a microenvironment favoring malignant colonization. The complex bone microenvironment produces an ever changing array of cytokines and growth factors. In this stud...
Evaluation of antiproliferative activity of red sorghum bran anthocyanin on a human breast cancer cell line (mcf-7) [0.03%]
评估红高粱麸 anthocyanin 对人乳腺癌细胞系（mcf-7）的抗增殖活性
P Suganya Devi,M Saravana Kumar,S Mohan Das
P Suganya Devi
Breast cancer is a leading cause of death in women worldwide both in the developed and developing countries. Thus effective treatment of breast cancer with potential antitumour drugs is important. In this paper, human breast cancer cell lin...
Current Status of Poly(ADP-ribose) Polymerase Inhibitors as Novel Therapeutic Agents for Triple-Negative Breast Cancer [0.03%]
聚腺苷二磷酸核糖聚合酶抑制剂治疗三阴性乳腺癌的最新研究进展
David J Hiller,Quyen D Chu
David J Hiller
Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer that is clinically defined as lacking estrogen and progesterone receptors, as well as being ERBB2 (HER-2) negative. Without specific therapeutic targets, TNBC carri...
Andrew A Davis,Virginia G Kaklamani
Andrew A Davis
Triple-negative breast cancers (TNBCs) are aggressive tumors with poor prognosis compared to other breast cancer subtypes. The evidence linking TNBC with the metabolic syndrome, which consists of central obesity, insulin resistance, impaire...
Expression of toll-like receptors on breast tumors: taking a toll on tumor microenvironment [0.03%]
toll样受体在乳腺肿瘤中的表达：对肿瘤微环境的影响
Debika Bhattacharya,Nabiha Yusuf
Debika Bhattacharya
Breast cancer remains a major cause of death in women in the developed world. As Toll-like receptors (TLRs) are widely expressed on tumor cells and play important roles in the initiation and progression of cancer, they may thus serve as imp...
Mazanah Muhamad,Sharan Merriam,Norhasmilia Suhami
Mazanah Muhamad
Traditional healing is a common practice in low and middle income countries such as Malaysia. Eighty percent of Malaysians consult traditional healers or "bomoh" at some time in their life for health-related issues. The purpose of our study...
Bromodomain-Containing Protein 4: A Dynamic Regulator of Breast Cancer Metastasis through Modulation of the Extracellular Matrix [0.03%]
溴结构域含有的蛋白质4通过调节细胞外基质动态调控乳腺癌的转移
Jude Alsarraj,Kent W Hunter
Jude Alsarraj
Metastasis is an extremely complex process that accounts for most cancer-related deaths. Malignant primary tumors can be removed surgically, but the cells that migrate, invade, and proliferate at distant organs are often the cells that prov...
Sudipa Saha Roy,Ratna K Vadlamudi
Sudipa Saha Roy
Metastatic breast cancer is a life-threatening stage of cancer and is the leading cause of death in advanced breast cancer patients. Estrogen signaling and the estrogen receptor (ER) are implicated in breast cancer progression, and the majo...