RKIP Suppresses Breast Cancer Metastasis to the Bone by Regulating Stroma-Associated Genes [0.03%]
RKIP通过调节与肿瘤间质相关的基因来抑制乳腺癌骨转移
Elena Bevilacqua,Casey A Frankenberger,Marsha Rich Rosner
Elena Bevilacqua
In the past decade cancer research has recognized the importance of tumorstroma interactions for the progression of primary tumors to an aggressive and invasive phenotype and for colonization of new organs in the context of metastasis. The ...
Luciane R Cavalli,Rachel E Ellsworth,Christoph Klein et al.
Luciane R Cavalli et al.
Keith D Amos,Barbara Adamo,Carey K Anders
Keith D Amos
Triple-negative breast cancer (TNBC) is an aggressive malignancy with a poor prognosis despite the high rates of response to chemotherapy. This scenario highlights the need to develop novel therapies and/or treatment strategies to reduce th...
Multidrug resistance in breast cancer: from in vitro models to clinical studies [0.03%]
乳腺癌的多药耐药性：从体外模型到临床研究
N S Wind,I Holen
N S Wind
The development of multidrug resistance (MDR) and subsequent relapse on therapy is a widespread problem in breast cancer, but our understanding of the underlying molecular mechanisms is incomplete. Numerous studies have aimed to establish t...
MRP8/ABCC11 expression is regulated by dexamethasone in breast cancer cells and is associated to progesterone receptor status in breast tumors [0.03%]
MRP8/ABCC11表达在乳腺癌细胞中由地塞米松调控并与乳腺肿瘤中的孕酮受体状态相关
Mylène Honorat,Aurélia Mesnier,Julie Vendrell et al.
Mylène Honorat et al.
The ATP-binding cassette multidrug resistance protein 8 (MRP8/ABCC11) mediates the excretion of anticancer drugs. ABCC11 mRNA and protein levels were enhanced by DEX (dexamethasone) and by PROG (progesterone) in MCF7 (progesterone receptor-...
Secretory carcinoma of male breast: case report and review of the literature [0.03%]
男性乳腺分泌性癌一例报告及文献复习
S Gabal,S Talaat
S Gabal
Secretory carcinoma is a rare low-grade breast carcinoma, initially termed "juvenile breast cancer," but it is now known to occur in adults of both sexes. It is the only epithelial tumor of the breast with a balanced translocation, t(12;15)...
Image quality of digital direct flat-panel mammography versus an indirect small-field CCD technique using a high-contrast phantom [0.03%]
高对比度模型下数字化平板乳腺摄影与间接型电荷耦合器件小视野技术图像质量的比较研究
Kathrin Barbara Krug,Hartmut Stützer,Peter Frommolt et al.
Kathrin Barbara Krug et al.
Objective: To compare the detection of microcalcifications on mammograms of an anthropomorphic breast phantom acquired by a direct digital flat-panel detector mammography system (FPM) versus a stereotactic breast biopsy s...
17α-ethynyl-5α-androstane-3α, 17β-diol treatment of MNU-induced mammary cancer in rats [0.03%]
N-甲基-N-硝基脲诱发的大鼠乳腺癌的17α-乙炔-5α-雄甾烷-3α,17β-二醇治疗
Clarence N Ahlem,James M Frincke,Steven K White et al.
Clarence N Ahlem et al.
N-methyl-N-nitrosourea (MNU) induces estrogen-dependent mammary tumors in female Lewis rats. We explored the antineoplastic activity of a synthetic androstane derivative, 17α-ethynyl-5α-androstane-3α, 17β-diol (HE3235), as a single agen...
Pathologic findings in MRI-guided needle core biopsies of the breast in patients with newly diagnosed breast cancer [0.03%]
新诊断乳腺癌患者磁共振引导空芯针活检的病理结果
K P Siziopikou,P Jokich,M Cobleigh
K P Siziopikou
The role of MRI in the management of breast carcinoma is rapidly evolving from its initial use for specific indications only to a more widespread use on all women with newly diagnosed early stage breast cancer. However, there are many conce...
Biological characteristics and medical treatment of breast cancer in young women-a featured population: results from the NORA study [0.03%]
年轻女性乳腺癌的生物学特点及治疗特征——以NORA研究数据为例
P Pronzato,G Mustacchi,A De Matteis et al.
P Pronzato et al.
Background: The present paper described the biological characteristics and clinical behavior of young women in the cohort NORA study Patients and methods:...