Racial differences in the use of adjuvant chemotherapy for breast cancer in a large urban integrated health system [0.03%]
大型城市综合卫生系统中乳腺癌辅助化疗使用的种族差异
Michael S Simon,Lois Lamerato,Richard Krajenta et al.
Michael S Simon et al.
Background. Racial differences in breast cancer survival may be in part due to variation in patterns of care. To better understand factors influencing survival disparities, we evaluated patterns of receipt of adjuvant chemotherapy among 2,2...
Selection of a MCF-7 Breast Cancer Cell Subpopulation with High Sensitivity to IL-1β: Characterization of and Correlation between Morphological and Molecular Changes Leading to Increased Invasiveness [0.03%]
高敏感性IL-1β乳腺癌MCF-7细胞亚群的选择：增加侵袭性的形态和分子变化的特征及关联研究
Eloy Andres Pérez-Yépez,Jorge-Tonatiuh Ayala-Sumuano,Alicia Maria Reveles-Espinoza et al.
Eloy Andres Pérez-Yépez et al.
Cancer and inflammation are closely related in tumor malignancy prognosis. Breast cancer MCF-7 cells have a poor invasive phenotype, although, under IL-1β stimulus, acquire invasive features. Cell response heterogeneity has precluded preci...
Triple-negative breast cancer [0.03%]
三阴性乳腺癌
Quyen D Chu,Tari King,Thelma Hurd
Quyen D Chu
Mechanisms of Resistance to Trastuzumab and Novel Therapeutic Strategies in HER2-Positive Breast Cancer [0.03%]
曲妥珠单抗耐药机制及阳性乳腺癌的新治疗策略HER2
Andrea L A Wong,Soo-Chin Lee
Andrea L A Wong
HER2-positive breast cancers have poorer prognosis and are prime candidates for molecular-targeted therapy because they are driven by the unique mechanism of HER2 oncogene addiction. While anti-HER2 agents such as trastuzumab and lapatinib ...
Outcome for patients with triple-negative breast cancer is not dependent on race/ethnicity [0.03%]
三阴性乳腺癌患者的预后与种族/民族无关
Quyen D Chu,Amanda E Henderson,Fred Ampil et al.
Quyen D Chu et al.
Introduction. Triple negative breast cancer (TNBC) is biologically aggressive and is associated with a worse prognosis. To understand the impact of race/ethnicity on outcome for patients with TNBC, confounding factors such as socioeconomic ...
Andra R Frost,Douglas R Hurst,Lalita A Shevde et al.
Andra R Frost et al.
PKCα and ERβ Are Associated with Triple-Negative Breast Cancers in African American and Caucasian Patients [0.03%]
PKCα和ERβ与非洲裔和高加索女性的三阴性乳腺癌相关
Debra A Tonetti,Weihua Gao,Diana Escarzaga et al.
Debra A Tonetti et al.
Although the incidence of breast cancer in the United States is higher in Caucasian women compared with African American women, African-American patients have more aggressive disease as characterized by a higher percentage of triple-negativ...
Sahar Shojaei,Mossa Gardaneh,Abbas Rahimi Shamabadi
Sahar Shojaei
Epidermal growth factor (EGF) family of receptors is involved in cell growth and differentiation. The human EGF2 (HER2) lacks natural ligands, and correlation between HER2 levels and carcinogenesis makes the receptor an ideal candidate for ...
The Microenvironmental Effect in the Progression, Metastasis, and Dormancy of Breast Cancer: A Model System within Bone Marrow [0.03%]
乳腺癌进展、转移和休眠的微环境效应：骨髓内的模型系统
Bobby Y Reddy,Philip K Lim,Kimberly Silverio et al.
Bobby Y Reddy et al.
Despite diagnostic advances, breast cancer remains the most prevalent cancer among women in the United States. The armamentarium of treatment options for metastatic disease is limited and mostly ineffective with regards to eradicating cance...
Zahraa I Khamis,Ziad J Sahab,Qing-Xiang Amy Sang
Zahraa I Khamis
Metastasis is the major cause of death for breast cancer patients. Tumors are heterogenous cellular entities composed of cancer cells and cells of the microenvironment in which they reside. A reciprocal dynamic interaction occurs between th...