Dennis R Holmes,Wesley Schooler,Robina Smith
Dennis R Holmes
When a woman is diagnosed with breast cancer many aspects of her physical, emotional, and sexual wholeness are threatened. The quickly expanding field of oncoplastic breast surgery aims to enhance the physician commitment to restore the pat...
Image-Based Treatment Planning of the Post-Lumpectomy Breast Utilizing CT and 3TMRI [0.03%]
基于图像的保乳术后乳房重建计划利用CT和3T MRI技术
Geraldine Jacobson,Gideon Zamba,Vicki Betts et al.
Geraldine Jacobson et al.
Accurate lumpectomy cavity definition is critical in breast treatment planning. We compared contouring lumpectomy cavity volume and cavity visualization score (CVS) with CT versus 3T MRI. 29 patients were imaged with CT and 3T MRI. Seven ad...
V Gowri Sree,K Udayakumar,R Sundararajan
V Gowri Sree
An attractive alternative treatment for malignant tumors that are refractive to conventional therapies, such as surgery, radiation, and chemotherapy, is electrical-pulse-mediated drug delivery. Electric field distribution of tissue/tumor is...
A role for estrogen receptor phosphorylation in the resistance to tamoxifen [0.03%]
雌激素受体磷酸化在托瑞米芬抗性中的作用
Renée de Leeuw,Jacques Neefjes,Rob Michalides
Renée de Leeuw
About two thirds of all human breast cancer cases are estrogen receptor positive. The drug of first choice for these patients is tamoxifen. However, about half of the recurrences after removal of the primary tumor are or become resistant to...
A Comparative Analysis of Biomarker Expression and Molecular Subtypes of Pure Ductal Carcinoma In Situ and Invasive Breast Carcinoma by Image Analysis: Relationship of the Subtypes with Histologic Grade, Ki67, p53 Overexpression, and DNA Ploidy [0.03%]
基于图像分析的原位导管癌和侵袭性乳腺癌生物标志物表达及分子亚型的比较分析：亚型与组织学分级、ki67、p53过表达及dna倍体的关系
Venetia R Sarode,Jeong S Han,Danielle H Morris et al.
Venetia R Sarode et al.
There is a paucity of data regarding molecular subtypes of pure ductal carcinoma in situ (pDCIS). We evaluated the expression of ER, PR, HER2, Ki67, and p53 and DNA ploidy in 118 pDCIS and 100 invasive breast carcinomas (IBCAs) by routine I...
Anastasia Pazaiti,Ian S Fentiman
Anastasia Pazaiti
Sentinel lymph node biopsy (SLNB) is a safe and accurate minimally invasive method for detecting axillary lymph node (ALN) involvement in the clinically negative axilla thereby reducing morbidity in patients who avoid unnecessary axillary l...
Differential gene expression in primary breast tumors associated with lymph node metastasis [0.03%]
与淋巴结转移相关的乳腺癌原发灶中的差异表达基因
Rachel E Ellsworth,Lori A Field,Brad Love et al.
Rachel E Ellsworth et al.
Lymph node status remains one of the most useful prognostic indicators in breast cancer; however, current methods to assess nodal status disrupt the lymphatic system and may lead to secondary complications. Identification of molecular signa...
Jonathan White,Raj Achuthan,Philip Turton et al.
Jonathan White et al.
Breast conservation surgery is available to the vast majority of women with breast cancer. The combination of neoadjuvant therapies and oncoplastic surgical techniques allows even large tumours to be managed with a breast-conserving approac...