The molecular biology of vestibular schwannomas and its association with hearing loss: a review [0.03%]
前庭神经鞘瘤的分子生物学及其与听力损失的关系：综述
Erika Celis-Aguilar,Luis Lassaletta,Miguel Torres-Martín et al.
Erika Celis-Aguilar et al.
Hearing loss is the most common symptom in patients with vestibular schwannoma (VS). In the past, compressive mechanisms caused by the tumoral mass and its growth have been regarded as the most likely causes of the hearing loss associated w...
Chengwei Li,Changxia Gong,Shuang Yu et al.
Chengwei Li et al.
The molecular players of circadian clock oscillation have been identified and extensively characterized. The epigenetic mechanisms behind the circadian gene expression control has also been recently studied, although there are still details...
Finding a balance: how diverse dosage compensation strategies modify histone h4 to regulate transcription [0.03%]
寻找平衡：多样化的剂量补偿策略如何修饰组蛋白H4来调节转录
Michael B Wells,Györgyi Csankovszki,Laura M Custer
Michael B Wells
Dosage compensation balances gene expression levels between the sex chromosomes and autosomes and sex-chromosome-linked gene expression levels between the sexes. Different dosage compensation strategies evolved in different lineages, but al...
Genetic Testing for Minors: Comparison between Italian and British Guidelines [0.03%]
未成年人基因检测：意大利和英国指导原则的比较
Pamela Tozzo,Luciana Caenazzo,Daniele Rodriguez
Pamela Tozzo
Genetic testing in children raises many important ethical, legal, and social issues. One of the main concerns is the ethically inappropriate genetic testing of minors. Various European countries established professional guidelines which ref...
Sebastián Chávez,David S Gross,Damien Hermand et al.
Sebastián Chávez et al.
Environmental heterogeneity and phenotypic divergence: can heritable epigenetic variation aid speciation? [0.03%]
环境异质性与表型分化：可遗传的表观遗传变异有助于物种形成吗？
Ruth Flatscher,Božo Frajman,Peter Schönswetter et al.
Ruth Flatscher et al.
The dualism of genetic predisposition and environmental influences, their interactions, and respective roles in shaping the phenotype have been a hot topic in biological sciences for more than two centuries. Heritable epigenetic variation m...
Transgenic epigenetics: using transgenic organisms to examine epigenetic phenomena [0.03%]
转基因表观遗传学：使用转基因生物检测表观遗传现象
Lori A McEachern
Lori A McEachern
Non-model organisms are generally more difficult and/or time consuming to work with than model organisms. In addition, epigenetic analysis of model organisms is facilitated by well-established protocols, and commercially-available reagents ...
Patrick Bateson
Patrick Bateson
Historically, evolutionary biologists have taken the view that an understanding of development is irrelevant to theories of evolution. However, the integration of several disciplines in recent years suggests that this position is wrong. The...
Epigenetics in social insects: a new direction for understanding the evolution of castes [0.03%]
表观遗传学在社会性昆虫中的作用——理解品级进化的新生长点
Susan A Weiner,Amy L Toth
Susan A Weiner
Epigenetic modifications to DNA, such as DNA methylation, can expand a genome's regulatory flexibility, and thus may contribute to the evolution of phenotypic plasticity. Recent work has demonstrated the importance of DNA methylation in alt...
Epigenetic mechanisms of genomic imprinting: common themes in the regulation of imprinted regions in mammals, plants, and insects [0.03%]
基因组印记的表观遗传机制：哺乳动物、植物和昆虫中印记区域调控中的共同主题
William A Macdonald
William A Macdonald
Genomic imprinting is a form of epigenetic inheritance whereby the regulation of a gene or chromosomal region is dependent on the sex of the transmitting parent. During gametogenesis, imprinted regions of DNA are differentially marked in ac...