Synergistic Effect of Geranylgeranyltransferase Inhibitor, GGTI, and Docetaxel on the Growth of Prostate Cancer Cells [0.03%]
GGTI与多西他赛对前列腺癌细胞生长的协同作用
Bin Han,Naohiro Fujimoto,Mizuki Kobayashi et al.
Bin Han et al.
Most advanced prostate cancers progress to castration resistant prostate cancer (CRPC) after a few years of androgen deprivation therapy and the prognosis of patients with CRPC is poor. Although docetaxel and cabazitaxel can prolong the sur...
Laparoscopic sentinel lymph node biopsy for prostate cancer: the relevance of locations outside the extended dissection area [0.03%]
腹腔镜下前列腺癌哨点淋巴结活检术的临床意义超出了扩大清扫区域定位的重要性
W Meinhardt,H G van der Poel,R A Valdés Olmos et al.
W Meinhardt et al.
Objective. To assess the relevance of sentinel lymph nodes (SNs) outside the extended pelvic lymph node dissection area (e-PLND). Patients and Methods. Evaluation of our laparoscopic SN procedures for prostate cancer patients of intermediat...
Prostate intrafraction translation margins for real-time monitoring and correction strategies [0.03%]
实时监控和校正策略下的前列腺治疗过程中的靶区追踪允许范围研究
Dale W Litzenberg,James M Balter,Scott W Hadley et al.
Dale W Litzenberg et al.
The purpose of this work is to determine appropriate radiation therapy beam margins to account for intrafraction prostate translations for use with real-time electromagnetic position monitoring and correction strategies. Motion was measured...
Lisa W Chu,Jamie Ritchey,Susan S Devesa et al.
Lisa W Chu et al.
African American men have among the highest prostate cancer incidence rates in the world yet rates among their African counterparts are unclear. In this paper, we compared reported rates among black men of Sub-Saharan African descent using ...
New insights into the androgen-targeted therapies and epigenetic therapies in prostate cancer [0.03%]
前列腺癌的雄激素靶向疗法和表观遗传学疗法的新见解
Abhijit M Godbole,Vincent C O Njar
Abhijit M Godbole
Prostate cancer is the most common cancer in men in the United States, and it is the second leading cause of cancer-related death in American men. The androgen receptor (AR), a receptor of nuclear family and a transcription factor, is the m...
Kenneth C Valkenburg,Bart O Williams
Kenneth C Valkenburg
The development and optimization of high-throughput screening methods has identified a multitude of genetic changes associated with human disease. The use of immunodeficient and genetically engineered mouse models that mimic the human disea...
A comparison of radical perineal, radical retropubic, and robot-assisted laparoscopic prostatectomies in a single surgeon series [0.03%]
单中心同一外科医师行经会阴、经耻骨后和机器人辅助腹腔镜前列腺癌根治术的临床疗效比较
Moben Mirza,Kevin Art,Logan Wineland et al.
Moben Mirza et al.
Objective. We sought to compare positive surgical margin rates (PSM), estimated blood loss (EBL), and quality of life outcomes (QOL) among perineal (RPP), retropubic (RRP), and robot-assisted laparoscopic (RALP) prostatectomies. Methods. Re...
Charnita M Zeigler-Johnson,Ann Tierney,Timothy R Rebbeck et al.
Charnita M Zeigler-Johnson et al.
Background. The goal of this paper was to examine neighborhood deprivation and prostate cancer severity. Methods. We studied African American and Caucasian prostate cancer cases from the Pennsylvania State Cancer Registry. Census tract-leve...
Development and External Validation of a Nomogram Predicting the Probability of Significant Gleason Sum Upgrading among Japanese Patients with Localized Prostate Cancer [0.03%]
预测局部前列腺癌患者Gleason评分显著升级概率列线图的建立与外部验证
Takashi Imamoto,Takanobu Utsumi,Makoto Takano et al.
Takashi Imamoto et al.
Objective. The aim of this study is to develop a prognostic model capable of predicting the probability of significant upgrading among Japanese patients. Methods. The study cohort comprised 508 men treated with RP, with available prostate-s...
Oncologic outcomes of asian men with clinically localized prostate cancer after extraperitoneal laparoscopic radical prostatectomy: a single-institution experience [0.03%]
经腹膜外腹腔镜根治性前列腺切除术后亚洲局限期前列腺癌患者的肿瘤结局：单中心经验报告
Huai-Ching Tai,Ming-Kuen Lai,Chao-Yuan Huang et al.
Huai-Ching Tai et al.
Purpose. To evaluate the midterm oncologic results of extraperitoneal laparoscopic radical prostatectomy (EPLRP) for Asian men with localized prostate cancer. Methods. Between 2004 and 2009, 218 men underwent EPLRP at an Asian tertiary hosp...