Potential inaccuracies in chloride measurements in patients with severe metabolic acidosis [0.03%]
重度代谢性酸中毒患者氯化物检测结果的潜在误差
Tetsuya Makiishi,Naomasa Nishimura,Keiko Yoshioka et al.
Tetsuya Makiishi et al.
Background. To address the cause(s) of the significant differences in chloride (Cl(-)) concentrations between point-of-care blood gas analyzers and central laboratory analyzers. Methods. Cl(-) concentrations measured simultaneously by a blo...
Influence of birth weight on the renal development and kidney diseases in adulthood: experimental and clinical evidence [0.03%]
出生体重对肾脏发育和成人肾病影响的实验证据及临床证据
Maria C P Franco,Vanessa Oliveira,Beatriz Ponzio et al.
Maria C P Franco et al.
Several clinical and experimental studies support the hypothesis that foetal programming is an important determinant of nephropathy, hypertension, coronary heart disease, and type 2 diabetes during adulthood. In this paper, the renal reperc...
Serum galactose-deficient IgA1 level is not associated with proteinuria in children with IgA nephropathy [0.03%]
血清半乳糖缺陷型IgA1水平与儿童IgA肾病蛋白尿无关
M Colleen Hastings,Sabahat Afshan,John T Sanders et al.
M Colleen Hastings et al.
Introduction. Percentage of galactose-deficient IgA1 (Gd-IgA1) relative to total IgA in serum was recently reported to correlate with proteinuria at time of sampling and during follow-up for pediatric and adult patients with IgA nephropathy...
Jorge Rojas-Rivera,Alberto Ortiz,Jesus Egido
Jorge Rojas-Rivera
Drugs targeting the renin-angiotensin-aldosterone system (RAAS) are the mainstay of therapy to retard the progression of proteinuric chronic kidney disease (CKD) such as diabetic nephropathy. However, diabetic nephropathy is still the first...
Emilio González-Parra,Carolina Gracia-Iguacel,Jesús Egido et al.
Emilio González-Parra et al.
Patients with renal impairment progressively lose the ability to excrete phosphorus. Decreased glomerular filtration of phosphorus is initially compensated by decreased tubular reabsorption, regulated by PTH and FGF23, maintaining normal se...
Overexpression of Delayed Rectifier K(+) Channels Promotes In situ Proliferation of Leukocytes in Rat Kidneys with Advanced Chronic Renal Failure [0.03%]
延迟整流钾通道过度表达促进慢性肾功能衰竭大鼠肾脏内白细胞原位增殖
Itsuro Kazama,Yoshio Maruyama,Yasuhiro Endo et al.
Itsuro Kazama et al.
Leukocytes, such as lymphocytes and macrophages, predominantly express delayed rectifier K(+) channels (Kv1.3), and the channels play crucial roles in the activation and proliferation of the cells. Since lymphocytes are activated in patient...
Comparison of Mortality between Japanese Peritoneal Dialysis and Hemodialysis Patients: A 5-Year Multicenter Follow-Up Study [0.03%]
日本血液透析与腹膜透析患者的生存率比较——一项为期五年的 multicenter 随访研究
Kazuko Suzuki,Tsuneo Konta,Kazunobu Ichikawa et al.
Kazuko Suzuki et al.
To examine the relationship between dialysis modality and prognosis in Japanese patients, we conducted a prospective multicenter observational study. We recruited 83 background-matched peritoneal dialysis (PD) and 83 hemodialysis (HD) patie...
Aihua Zhang,Songming Huang
Aihua Zhang
Aims. Proteinuria not only is a sign of kidney damage, but also is involved in the progression of renal diseases as an independent pathologic factor. Clinically, glomerular proteinuria is most commonly observed, which relates to structural ...
Congenital anomalies of the kidney and urinary tract: a genetic disorder? [0.03%]
肾脏和泌尿系统的先天畸形：一种遗传性疾病吗？
Ihor V Yosypiv
Ihor V Yosypiv
Congenital anomalies of the kidney and urinary tract (CAKUTs) occur in 3-6 per 1000 live births, account for the most cases of pediatric end-stage kidney disease (ESKD), and predispose an individual to hypertension and cardiovascular diseas...
Akihiro Tojo,Satoshi Kinugasa
Akihiro Tojo
Albumin is filtered through the glomerulus with a sieving coefficient of 0.00062, which results in approximately 3.3 g of albumin filtered daily in human kidneys. The proximal convoluted tubule reabsorbs 71%, the loop of Henle and distal tu...