Primary molecular disorders and secondary biological adaptations in bartter syndrome [0.03%]
巴特氏综合征的主要分子缺陷和次要生物适应机制
Georges Deschênes,Marc Fila
Georges Deschênes
Bartter syndrome is a hereditary disorder that has been characterized by the association of hypokalemia, alkalosis, and the hypertrophy of the juxtaglomerular complex with secondary hyperaldosteronism and normal blood pressure. By contrast,...
Incremental peritoneal dialysis favourably compares with hemodialysis as a bridge to renal transplantation [0.03%]
腹膜透析与血液透析作为肾脏移植前的过渡治疗效果良好
Alessandro Domenici,Maria Cristina Comunian,Loredana Fazzari et al.
Alessandro Domenici et al.
Background. The value of incremental peritoneal dialysis (PD) as a bridge to renal transplantation (Tx) has not been specifically addressed. Methods. All consecutive Stage 5 CKD patients with at least 1 year predialysis followup, starting i...
Maddalena Gigante,Matteo Piemontese,Loreto Gesualdo et al.
Maddalena Gigante et al.
Nephrotic syndrome is an heterogeneous disease characterized by increased permeability of the glomerular filtration barrier for macromolecules. Podocytes, the visceral epithelial cells of glomerulus, play critical role in ultrafiltration of...
J-C Davin,N W Rutjes
J-C Davin
Idiopathic nephrotic syndrome (INS) is the most frequent form of NS in children. INS is defined by the association of the clinical features of NS with renal biopsy findings of minimal changes, focal segmental glomerulosclerosis (FSGS), or m...
Hemolytic uremic syndrome: new developments in pathogenesis and treatment [0.03%]
溶血性尿毒综合征：发病机制及治疗的新进展
Olivia Boyer,Patrick Niaudet
Olivia Boyer
Hemolytic uremic syndrome is defined by the characteristic triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. In children, most cases of HUS are caused by Shiga-toxin-producing bacteria, especially Escher...
C Kennedy,C McCarthy,S Alken et al.
C Kennedy et al.
Pressure related complications such as abdominal wall hernias occur with relative frequency in patients on peritoneal dialysis. Less frequently, a transudative pleural effusion containing dialysate can develop. This phenomenon appears to be...
The hyponatremic hypertensive syndrome in a preterm infant: a case of severe hyponatremia with neurological sequels [0.03%]
早产儿低钠性高血压综合征1例报告及相关文献复习
Vera van Tellingen,Marc Lilien,Jos Bruinenberg et al.
Vera van Tellingen et al.
Objective. To report the irreversible severe neurological symptoms following the hyponatremic hypertensive syndrome (HHS) in an infant after umbilical arterial catheterization. Design. Case report with review of the literature. Setting. Neo...
Fibroblast growth factor 23 predicts left ventricular mass and induces cell adhesion molecule formation [0.03%]
纤维芽细胞生长因子23可预测左心室质量并诱导细胞黏附分子形成
Kathryn K Stevens,Emily P McQuarrie,William Sands et al.
Kathryn K Stevens et al.
Elevated FGF-23 is a predictor of mortality and is associated with LVH in CKD. It may be a biomarker or a direct toxin. We assessed the relationship between FGF-23 and LVH in CKD using CMRI. In vitro we studied the effect of phosphate, FGF-...
Maki Urushihara,Shoji Kagami
Maki Urushihara
While most circulating angiotensinogen (AGT) is synthesized in the liver, the kidneys also produce AGT. Recently, we reported that urinary AGT is mainly originated from AGT. Using newly developed human AGT ELISA, we measured urinary AGT lev...
Daniel P Casella,Jeffrey J Tomaszewski,Michael C Ost
Daniel P Casella
Posterior urethral valves occur in 1 : 5000 live births. Despite the high prevalence, the few children that survive do poorly, with over 50% progressing to ESRD in 10 years. The gold standard for post-natal diagnosis is voiding cystourethro...