Abnormal behaviors and microstructural changes in white matter of juvenile mice repeatedly exposed to amphetamine [0.03%]
反复接触安非他明对小鼠不良行为和白质微结构的影响研究
Hong-Ju Yang,Lijun Wang,Qiang Cheng et al.
Hong-Ju Yang et al.
Amphetamine (AMP) is an addictive CNS stimulant and has been commonly abused by adolescents and young adults, during which period brain white matter is still developing. This study was to examine the effect of a nonneurotoxic AMP on the whi...
Cannabinoids for the treatment of schizophrenia? A balanced neurochemical framework for both adverse and therapeutic effects of cannabis use [0.03%]
大麻素治疗精神分裂症吗？一个平衡的神经化学框架来解释大麻使用带来的不良和治疗效应
Carissa M Coulston,Michael Perdices,Antony F Henderson et al.
Carissa M Coulston et al.
Recent studies have found that cannabinoids may improve neuropsychological performance, ameliorate negative symptoms, and have antipsychotic properties for a subgroup of the schizophrenia population. These findings are in contrast to the lo...
Randomized Controlled Trial of Clozapine and CBT for First-Episode Psychosis with Enduring Positive Symptoms: A Pilot Study [0.03%]
氯氮平和认知行为治疗联合治疗首发精神病持续阳性症状患者的随机对照试验：一项试点研究
J Edwards,J Cocks,P Burnett et al.
J Edwards et al.
Here we report the results of a pilot study investigating the relative and combined effects of a 12 week course of clozapine and CBT in first-episode psychosis patients with prominent ongoing positive symptoms following their initial treatm...
Ultrastructural alterations of myelinated fibers and oligodendrocytes in the prefrontal cortex in schizophrenia: a postmortem morphometric study [0.03%]
精神分裂症额叶皮层髓鞘纤维和少突胶质细胞的超微结构变化：一项死后形态学研究
Natalya A Uranova,Olga V Vikhreva,Valentina I Rachmanova et al.
Natalya A Uranova et al.
Schizophrenia is believed to result from altered neuronal connectivity and impaired myelination. However, there are few direct evidence for myelin abnormalities in schizophrenia. We performed electron microscopic study of myelinated fibers ...
Clinical Practice Associated with a Switch from and to Ziprasidone during Routine Inpatient Treatment of Patients with Schizophrenia [0.03%]
精神分裂症住院患者的常规治疗中从换用齐拉西酮到停用齐拉西酮的临床实践研究
Matthias J Müller
Matthias J Müller
Ziprasidone (ZIP) shows a low propensity for metabolic side effects but can prolong QTc time. It is unclear how these features translate into clinical reality. Charts of inpatients with schizophrenia and switched from (ZIP - , n = 27) or to...
Haiyun Xu,Vahram Haroutunian,George Bartzokis et al.
Haiyun Xu et al.
Age-related increase in the number of oligodendrocytes is dysregulated in schizophrenia and mood disorders [0.03%]
精神分裂症和情绪障碍患者的少突胶质细胞数量随年龄增长而增加的机制失调
Victor Vostrikov,Natalya Uranova
Victor Vostrikov
The postnatal maturation of the human prefrontal cortex is associated with substantial increase of number of oligodendrocytes. Previously, we reported decreased numerical density of oligodendrocytes in the prefrontal cortex in schizophrenia...