Prenatal and Postnatal Epigenetic Programming: Implications for GI, Immune, and Neuronal Function in Autism [0.03%]
孕期和产后表观遗传编程：自闭症胃肠、免疫和神经元功能的暗示
Mostafa I Waly,Mady Hornig,Malav Trivedi et al.
Mostafa I Waly et al.
Although autism is first and foremost a disorder of the central nervous system, comorbid dysfunction of the gastrointestinal (GI) and immune systems is common, suggesting that all three systems may be affected by common molecular mechanisms...
Elizabeth Pellicano
Elizabeth Pellicano
Autism is a common and often highly debilitating neurodevelopmental condition, whose core behavioral features are believed to be rooted in disrupted neurocognitive processes, including especially "executive function." Researchers have predo...
Sertraline may improve language developmental trajectory in young children with fragile x syndrome: a retrospective chart review [0.03%]
塞拉嗪或可改善儿童易位性综合征的语言发育轨迹：基于回顾性病历分析的结果
Tri Indah Winarni,Weerasak Chonchaiya,Evan Adams et al.
Tri Indah Winarni et al.
Young children with fragile X syndrome (FXS) often experience anxiety, irritability, and hyperactivity related to sensory hyperarousal. However, there are no medication recommendations with documented efficacy for children under 5 years old...
Intracellular and extracellular redox status and free radical generation in primary immune cells from children with autism [0.03%]
自闭症儿童原发性免疫细胞内的氧化还原状态和自由基生成
Shannon Rose,Stepan Melnyk,Timothy A Trusty et al.
Shannon Rose et al.
The modulation of the redox microenvironment is an important regulator of immune cell activation and proliferation. To investigate immune cell redox status in autism we quantified the intracellular glutathione redox couple (GSH/GSSG) in res...
Anthony R Torres,Jonna B Westover,Allen J Rosenspire
Anthony R Torres
The human leukocyte antigen (HLA) genes on chromosome 6 are instrumental in many innate and adaptive immune responses. The HLA genes/haplotypes can also be involved in immune dysfunction and autoimmune diseases. It is now becoming apparent ...
Maureen E Angell,Hedda Meadan,Julia B Stoner
Maureen E Angell
The purpose of this study was to explore the experiences of siblings of individuals with autism spectrum disorders (ASDs) and identify their self-reported support needs. We conducted in-person semi-structured interviews with 12 siblings age...
Is autism a member of a family of diseases resulting from genetic/cultural mismatches? Implications for treatment and prevention [0.03%]
自闭症是一种由于基因/文化不匹配而导致的疾病的家族成员吗？对治疗和预防的启示
Staci D Bilbo,John P Jones,William Parker
Staci D Bilbo
Several lines of evidence support the view that autism is a typical member of a large family of immune-related, noninfectious, chronic diseases associated with postindustrial society. This family of diseases includes a wide range of inflamm...
High complement factor I activity in the plasma of children with autism spectrum disorders [0.03%]
自闭症谱系障碍儿童血浆补体因子I活性升高
Naghi Momeni,Lars Brudin,Fatemeh Behnia et al.
Naghi Momeni et al.
Autism spectrum disorders (ASDs) are neurodevelopmental and behavioural syndromes affecting social orientation, behaviour, and communication that can be classified as developmental disorders. ASD is also associated with immune system abnorm...
Britta L Fiksdal,Daniel Houlihan,Aaron C Barnes
Britta L Fiksdal
The purpose of this paper is to review and critique studies that have been conducted on dolphin-assisted therapy for children with various disorders. Studies have been released claiming swimming with dolphins is therapeutic and beneficial f...