Subjects with Discordant Airways Obstruction: Lost between Spirometric Definitions of COPD [0.03%]
游离于COPD定义之外的不一致气流受限患者
Bernd Lamprecht,Lea Schirnhofer,Bernhard Kaiser et al.
Bernd Lamprecht et al.
Background. Since the FEV1/FVC ratio declines with age, using the fixed ratio of 0.70 leads to overdiagnosis of COPD in older populations and underdiagnosis among young adults. Objective. To evaluate whether discordant obstructive cases (FE...
E Bargagli,A Prasse,C Olivieri et al.
E Bargagli et al.
Idiopathic pulmonary fibrosis (IPF) is a severe, rapidly progressive diffuse lung disease. Several pathogenetic mechanisms have been hypothesized on the basis of the fibrotic lung damage occurring in this disease, and a potential profibroti...
Diffuse alveolar damage: a common phenomenon in progressive interstitial lung disorders [0.03%]
弥漫性肺泡损伤：进行性间质性肺疾病的常见现象
Riitta Kaarteenaho,Vuokko L Kinnula
Riitta Kaarteenaho
It has become obvious that several interstitial lung diseases, and even viral lung infections, can progress rapidly, and exhibit similar features in their lung morphology. The final histopathological feature, common in these lung disorders,...
Relative Roles of TGF-β and IGFBP-5 in Idiopathic Pulmonary Fibrosis [0.03%]
TGF-β和IGFBP-5在特发性肺纤维化发病机制中的相对作用
A Sureshbabu,E Tonner,G J Allan et al.
A Sureshbabu et al.
Although most evident in the skin, the process of scarring, or fibrosis, occurs in all major organs because of impaired epithelial self-renewal. No current therapy exists for Idiopathic pulmonary fibrosis. The major profibrotic factor is TG...