Update on pharmaceutical and minimally invasive management strategies for chronic obstructive pulmonary disease [0.03%]
慢性阻塞性肺疾病的药物和微创管理策略的更新
Rokhsara Rafii,Timothy E Albertson,Samuel Louie et al.
Rokhsara Rafii et al.
Chronic obstructive pulmonary disease (COPD) is a debilitating pulmonary disorder with systemic effects, and it is the fourth leading cause of death in the United States. COPD patients not only develop respiratory limitations, but can also ...
Ganciclovir antiviral therapy in advanced idiopathic pulmonary fibrosis: an open pilot study [0.03%]
高细胞毒性的甘昔洛韦抗病毒疗法治疗进行性先天性肺纤维化开放式试验研究
J J Egan,H I Adamali,S S Lok et al.
J J Egan et al.
Hypothesis. Repeated epithelial cell injury secondary to viruses such as Epstein Barr and subsequent dysfunctional repair may be central to the pathogenesis of IPF. In this observational study, we evaluated whether a combination of standard...
Pulmonary Arteriovenous Malformation (AVM) Causing Tension Hemothorax in a Pregnant Woman Requiring Emergent Cesarean Delivery [0.03%]
妊娠期女性因肺动静脉畸形(AVM)导致张力性血胸急诊剖宫产术一例
Nidhi Sood,Nikhil Sood,Vibhu Dhawan
Nidhi Sood
Pulmonary arteriovenous malformations (PAVMs), although most commonly congenital, are usually detected later in life. We present a case of a 25-year-old woman with no previous history of AVM or telangiectasia, who presented with life-threat...
Scott Burgess,Peter Sly,Sunalene Devadason
Scott Burgess
Suboptimal adherence with preventive medication is common and often unrecognised as a cause of poor asthma control. A number of risk factors for nonadherence have emerged from well-conducted studies. Unfortunately, patient report a physicia...
Rheumatoid arthritis-associated interstitial lung disease: diagnostic dilemma [0.03%]
与类风湿关节炎相关的间质性肺病：诊断困境
Mark J Hamblin,Maureen R Horton
Mark J Hamblin
Interstitial lung disease (ILD) is an increasingly recognized complication of rheumatoid arthritis (RA) contributing to significantly increased morbidity and mortality. Diagnosis can be challenging since patients are unlikely to report dysp...
Quantitative CT: Associations between Emphysema, Airway Wall Thickness and Body Composition in COPD [0.03%]
CT量化：COPD患者的肺气肿、气道壁厚度与机体成分的关系
Erica P A Rutten,Thomas B Grydeland,Sreekumar G Pillai et al.
Erica P A Rutten et al.
The objective of the present study was to determine the association between CT phenotypes-emphysema by low attenuation area and bronchitis by airway wall thickness-and body composition parameters in a large cohort of subjects with and witho...
Postoperative Acute Exacerbation of IPF after Lung Resection for Primary Lung Cancer [0.03%]
肺癌术后急性间质性肺疾病加重
Atsushi Watanabe,Nobuyoshi Kawaharada,Tetsuya Higami
Atsushi Watanabe
Idiopathic pulmonary fibrosis (IPF) is characterized by slowly progressive respiratory dysfunction. Nevertheless, some IPF patients experience acute exacerbations generally characterized by suddenly worsening and fatal respiratory failure w...
Gradual increase of high mobility group protein b1 in the lungs after the onset of acute exacerbation of idiopathic pulmonary fibrosis [0.03%]
特发性肺纤维化急性加重后高移动组蛋白B1在肺组织中的逐渐升高现象
Masahito Ebina,Hiroyuki Taniguchi,Taku Miyasho et al.
Masahito Ebina et al.
The pathogenesis of acute exacerbation of idiopathic pulmonary fibrosis (IPF) remains to be elucidated. To evaluate the roles of inflammatory mediators in acute exacerbation, the concentrations of high mobility group protein B1 (HMGB1), a c...
Mike Althaus,Wolfgang G Clauss,Martin Fronius
Mike Althaus
The development of pulmonary edema can be considered as a combination of alveolar flooding via increased fluid filtration, impaired alveolar-capillary barrier integrity, and disturbed resolution due to decreased alveolar fluid clearance. An...
A Normal Range of KL-6/MUC1 Independent of Elevated SP-D Indicates a Better Prognosis in the Patients with Honeycombing on High-Resolution Computed Tomography [0.03%]
KL-6/MUC1正常范围独立于SP-D升高表明高分辨率计算机断层扫描 honeycombing患者的较好预后
Shu Hisata,Yuichiro Kimura,Naoko Shibata et al.
Shu Hisata et al.
Both SP-D and KL-6/MUC1 are established biomarkers of the interstitial pneumonias, including idiopathic pulmonary fibrosis (IPF), but the causes and clinical outcomes based on their independent effects are not known. Eleven asymptomatic pat...