Potential role of the inflammasome-derived inflammatory cytokines in pulmonary fibrosis [0.03%]
炎症小体衍生的炎性细胞因子在肺纤维化中可能的作用
Rupa Biswas,Melisa Bunderson-Schelvan,Andrij Holian
Rupa Biswas
Pulmonary fibrosis is a progressive, disabling disease with mortality rates that appear to be increasing in the western population, including the USA. There are over 140 known causes of pulmonary fibrosis as well as many unknown causes. Tre...
Patient characteristics in persistent pulmonary hypertension of the newborn [0.03%]
持续性肺动脉高压的新生儿患者特征分析
M T R Roofthooft,A Elema,K A Bergman et al.
M T R Roofthooft et al.
Objective. To assess the impact of PPHN on mortality, morbidity, and behavioural skills. Methods. A retrospective observational study of 143 newborns with PPHN, over an 11-year period, using objective health-status data from medical records...
Quantification and evaluation of the role of antielastin autoantibodies in the emphysematous lung [0.03%]
抗弹性蛋白自身抗体在肺气肿发病机制中的作用及评估
Teck Boon Low,Catherine M Greene,Shane J ONeill et al.
Teck Boon Low et al.
Chronic obstructive pulmonary disease (COPD) may be an autoimmune disease. Smoking causes an imbalance of proteases and antiproteases in the lung resulting in the generation of elastin peptides that can potentially act as autoantigens. Simi...
Rapamycin Regulates Bleomycin-Induced Lung Damage in SP-C-Deficient Mice [0.03%]
雷帕霉素调节SP-C缺陷小鼠中博来霉素致肺损伤
Satish K Madala,Melissa D Maxfield,Cynthia R Davidson et al.
Satish K Madala et al.
Injury to the distal respiratory epithelium has been implicated as an underlying cause of idiopathic lung diseases. Mutations that result in SP-C deficiencies are linked to a small subset of spontaneous and familial cases of interstitial lu...
Rajamma Mathew
Rajamma Mathew
A wide variety of cardiopulmonary and systemic diseases are known to lead to pulmonary hypertension (PH). A number of signaling pathways have been implicated in PH; however, the precise mechanism/s leading to PH is not yet clearly understoo...
Factors influencing oxidative imbalance in pulmonary fibrosis: an immunohistochemical study [0.03%]
特发性肺纤维化中氧化应激失衡的影响因素:免疫组化研究
Simona Inghilleri,Patrizia Morbini,Ilaria Campo et al.
Simona Inghilleri et al.
Background. Idiopathic Pulmonary Fibrosis (IPF) is a fatal lung disease of unknown etiology characterized by interstitial fibrosis determining irreversible distortion of pulmonary architecture. Reactive oxygen species (ROS) and markers of o...
Effects of ischemic acute kidney injury on lung water balance: nephrogenic pulmonary edema? [0.03%]
缺血性急性肾损伤对肺水平衡的影响:肾源性肺水肿?
Rajit K Basu,Derek Wheeler
Rajit K Basu
Pulmonary edema worsens the morbidity and increases the mortality of critically ill patients. Mechanistically, edema formation in the lung is a result of net flow across the alveolar capillary membrane, dependent on the relationship of hydr...
Todd L Kiefer,Thomas M Bashore
Todd L Kiefer
Pulmonary hypertension (PH) is the end result of a variety of diverse pathologic processes. The chronic elevation in pulmonary artery pressure often leads to right ventricular pressure overload and subsequent right ventricular failure. In p...
Melissa L Bates,Emily T Farrell,Marlowe W Eldridge
Melissa L Bates
The question of whether pulmonary edema develops during exercise on land is controversial. Yet, the development of pulmonary edema during swimming and diving is well established. This paper addresses the current controversies that exist in ...
Eric A Carter,Michael S Koehle
Eric A Carter
Pulmonary edema has been reported in SCUBA divers, apnea divers, and long-distance swimmers however, no instances of pulmonary edema in triathletes exist in the scientific literature. Pulmonary edema may cause seizures and loss of conscious...