T Hassan,M Al-Alawi,S H Chotirmall et al.
T Hassan et al.
Pleural fluid analysis yields important diagnostic information in pleural effusions in combination with clinical history, examination, and radiology. For more than 30 years, the initial and most pragmatic step in this process is to determin...
Lipid-Laden Alveolar Macrophages and pH Monitoring in Gastroesophageal Reflux-Related Respiratory Symptoms [0.03%]
胃食管反流相关呼吸系统症状的肺泡巨噬细胞脂质蓄积和pH监测
R Kitz,H J Boehles,M Rosewich et al.
R Kitz et al.
Lipid-laden alveolar macrophages and pH monitoring have been used in the diagnosis of chronic aspiration in children with gastroesophageal reflux (GER). This study was conducted to prove a correlation between the detection of alimentary pul...
Airway Remodelling in Asthma and COPD: Findings, Similarities, and Differences Using Quantitative CT [0.03%]
哮喘和慢性阻塞性肺疾病气道重塑的CT定量研究：发现、相似性和差异性
Gaël Dournes,François Laurent
Gaël Dournes
Airway remodelling is a well-established feature in asthma and chronic obstructive lung disease (COPD), secondary to chronic airway inflammation. The structural changes found on pathological examination of remodelled airway wall have been s...
Bruna de Campos Guimarães E Figueiredo,Cássio da Cunha Ibiapina
Bruna de Campos Guimarães E Figueiredo
Objective. The present study aims at reviewing the main publications on the use of macrolides as immunomodulators in patients with noncystic fibrosis bronchiectasis. Source of Data. The Medline database was our source of data for this resea...
Perspectives of Pulmonologists on the 2009-2010 H1N1 Vaccination Effort [0.03%]
美国 pulmonologist 对于 2009-2010 年 H1N1疫苗 接种工作的看法
Sarah J Clark,Anne E Cowan,Pascale M Wortley
Sarah J Clark
Persons with high-risk conditions such as asthma were a target group for H1N1 vaccine recommendations. We conducted a mailed survey of a national sample of pulmonologists to understand their participation in the 2009-2010 H1N1 vaccine campa...
William Dubinski,Natasha B Leighl,Ming-Sound Tsao et al.
William Dubinski et al.
The pathologic diagnosis of lung cancer historically has relied primarily on morphologic features of tumors in histologic sections. With the emergence of new targeted therapies, the pathologist is called upon increasingly to provide not onl...
A Picchianti Diamanti,V Germano,E Bizzi et al.
A Picchianti Diamanti et al.
Interstitial lung disease (ILD) represents a severe manifestation in connective tissue diseases (CTD), with an overall incidence of 15%, and it is still a challenge for clinicians evaluation and management. ILD is the most common manifestat...
Cigarette-Smoke-Induced Dysregulation of MicroRNA Expression and Its Role in Lung Carcinogenesis [0.03%]
吸烟通过微调microRNA表达促进肺癌发生的作用机制研究进展
Rebecca Russ,Frank J Slack
Rebecca Russ
Dysregulation of microRNAs (miRNAs), particularly their downregulation, has been widely shown to be associated with the development of lung cancer. Downregulation of miRNAs leads to the overactivation of their oncogene targets, while upregu...
The Frequency of Epidermal Growth Factor Receptor Mutation of Nonsmall Cell Lung Cancer according to the Underlying Pulmonary Diseases [0.03%]
不同基础肺疾病非小细胞肺癌表皮生长因子受体突变频率分布差异研究
Kazuhiro Usui,Tomonori Ushijima,Yoshiaki Tanaka et al.
Kazuhiro Usui et al.
Background. Although epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are effective in patients with nonsmall cell lung cancer with epidermal growth factor receptor (EGFR) mutation, EGFR-TKIs have a risk of inducing f...
The PPARγ Agonist Rosiglitazone Is Antifibrotic for Scleroderma Lung Fibroblasts: Mechanisms of Action and Differential Racial Effects [0.03%]
PPARγ激动剂罗格列酮对硬皮病成纤维细胞的抗纤维化作用：作用机制及种族差异效应
Galina S Bogatkevich,Kristin B Highland,Tanjina Akter et al.
Galina S Bogatkevich et al.
We present novel data demonstrating that the expression of PPARγ is reduced in lung fibroblasts from black SSc-ILD patients as compared to white patients. Activating PPARγ with the agonist rosiglitazone increased the expression of MMP-1 a...