Symptom Burden, Medication Detriment, and Support for the Use of the 15D Health-Related Quality of Life Instrument in a Chronic Pain Clinic Population [0.03%]
慢性疼痛门诊患者的症状负担、药物危害及使用15D健康相关生活质量量表的支持度研究
Bruce D Dick,Saifudin Rashiq,Michelle J Verrier et al.
Bruce D Dick et al.
Chronic noncancer pain is a prevalent problem associated with poor quality of life. While symptom burden is frequently mentioned in the literature and clinical settings, this research highlights the considerable negative impact of chronic p...
Synaptic conversion of chloride-dependent synapses in spinal nociceptive circuits: roles in neuropathic pain [0.03%]
脊髓痛觉回路中氯离子依赖性突触的突触转换在神经病理性疼痛中的作用
Mark S Cooper,Adam S Przebinda
Mark S Cooper
Electrophysiological conversion of chloride-dependent synapses from inhibitory to excitatory function, as a result of aberrant neuronal chloride homeostasis, is a known mechanism for the genesis of neuropathic pain. This paper examines theo...
Paracetamol and the placebo effect in osteoarthritis trials: a missing link? [0.03%]
对氨基酚和关节炎临床试验中的安慰剂效应：缺失的环节？
Henning Zeidler
Henning Zeidler
This paper addresses the role of paracetamol in placebo-controlled osteoarthritis (OA) trials and the potential contribution to the large placebo response in such trials. Paracetamol is used as rescue medication in nearly all OA placebo-con...
Sedation and analgesia in intensive care: a comparison of fentanyl and remifentanil [0.03%]
重症监护病房镇静镇痛中芬太尼与雷米芬太尼的比较研究
F Cevik,M Celik,P M Clark et al.
F Cevik et al.
Optimal sedation and analgesia are of key importance in intensive care. The aim of this study was to assess the quality of sedoanalgesia and outcome parameters in regimens containing midazolam and either fentanyl or remifentanil. A prospect...
Repeated muscle injury as a presumptive trigger for chronic masticatory muscle pain [0.03%]
反复发生的肌肉损伤作为慢性咀嚼肌痛的假设触发因素
Dean Dessem,Richard M Lovering
Dean Dessem
skeletal muscles sustain a significant loss of maximal contractile force after injury, but terminally damaged fibers can eventually be replaced by the growth of new muscle (regeneration), with full restoration of contractile force over time...
Patterns of pain and functional improvement in patients with bone metastases after conventional external beam radiotherapy and a telephone validation study [0.03%]
常规体外放射治疗骨转移患者的疼痛及功能改善规律研究和电话随访研究
Liang Zeng,Arjun Sahgal,Liying Zhang et al.
Liang Zeng et al.
Patients experiencing lower body pain resulting from bone metastases have greater levels of functional interference than those with upper body pain. The purpose of this study was to assess the levels of interference caused by pain after tre...
Oral-parenteral conversion factor for morphine in palliative cancer care: a prospective randomized crossover pilot study [0.03%]
晚期癌症患者缓和医疗中口服换算静脉注射吗啡的转换系数：一项前瞻性随机交叉试验
Jan Starlander,Christina Melin-Johansson,Håkan Jonsson et al.
Jan Starlander et al.
Objective. This pilot study clinically tests whether a conversion factor of 2 to 1 is appropriate when changing from oral to parenteral morphine administration in the treatment of cancer-related nociceptive pain and calculates the size of a...
Evaluation of diagnosis techniques used for spinal injury related back pain [0.03%]
评估脊髓损伤相关背痛诊断技术的有效性
Meaghan Janssen,Aliaa Nabih,Walied Moussa et al.
Meaghan Janssen et al.
Back pain is a prevalent condition affecting much of the population at one time or the other. Complications, including neurological ones, can result from missed or mismanaged spinal abnormalities. These complications often result in serious...
Arnica/Hydroxyethyl salicylate combination spray for ankle distortion: a four-arm randomised double-blind study [0.03%]
一种花豹抑心膏/羟乙基水杨酸盐组合喷雾剂治疗踝关节扭伤：四组随机双盲研究
Miroslav Kučera,Pavel Kolar,Milos Barna et al.
Miroslav Kučera et al.
570 patients with acute ankle joint distortion were randomized to four treatment groups: a combination spray of arnica tincture and hydroxyethyl salicylate (HES; group A, n = 228), arnica (B, n = 57), HES (C, n = 228), and placebo (D, n = 5...
Pain and efficacy rating of a microprocessor-controlled metered injection system for local anaesthesia in minor hand surgery [0.03%]
微处理器控制的局部麻醉定量注射系统的疼痛和疗效评价在手外科小手术中的评价
André S Nimigan,Bing Siang Gan
André S Nimigan
Purpose. Little attention has been given to syringe design and local anaesthetic administration methods. A microprocessor-controlled anaesthetic delivery device has become available that may minimize discomfort during injection. The purpose...