The effect of topical local anesthetics on thermal pain sensitivity in patients with irritable bowel syndrome [0.03%]
局部麻醉剂对肠易激综合征患者热痛敏感性的影响
Anthony Rodrigues,Christopher D King,Fong Wong et al.
Anthony Rodrigues et al.
Generalized hypersensitivity that extends into somatic areas is common in patients with irritable bowel syndrome (IBS). The sensitized state, particularly assessed by experimental methods, is known to persist even during remissions of clini...
Primary afferent nociceptor as a target for the relief of pain [0.03%]
-primary afferent nociceptor在疼痛缓解中的作用-
Carlos A Parada,Claudia H Tambeli,Paul G Green et al.
Carlos A Parada et al.
Efficacy and Safety of Duloxetine in Patients with Chronic Low Back Pain Who Used versus Did Not Use Concomitant Nonsteroidal Anti-Inflammatory Drugs or Acetaminophen: A Post Hoc Pooled Analysis of 2 Randomized, Placebo-Controlled Trials [0.03%]
度洛西汀治疗慢性下腰痛患者合并使用与不使用非甾体抗炎药或对乙酰氨基酚的疗效和安全性：来自随机、安慰剂对照试验的事后汇总分析
Vladimir Skljarevski,Peng Liu,Shuyu Zhang et al.
Vladimir Skljarevski et al.
This subgroup analysis assessed the efficacy of duloxetine in patients with chronic low back pain (CLBP) who did or did not use concomitant nonsteroidal anti-inflammatory drugs (NSAIDs) or acetaminophen (APAP). Data were pooled from two 13-...
The influence of pain distribution on walking velocity and horizontal ground reaction forces in patients with low back pain [0.03%]
疼痛分布对腰痛患者步行速度及水平地面反应力的影响
Maureen J Simmonds,C Ellen Lee,Bruce R Etnyre et al.
Maureen J Simmonds et al.
Objective. The primary purpose of this paper was to evaluate the influence of pain distribution on gait characteristics in subjects with low back problems (LBP) during walking at preferred and fastest speeds. Design. Cross-sectional, observ...
Richard H Rech,David J Mokler,Shannon L Briggs
Richard H Rech
The authors review the opioid literature for evidence of increased analgesia and reduced adverse side effects by combining mu-opioid-receptor (MOR) agonists, kappa-opioid-receptor (KOR) agonists, and nonselective low-dose-opioid antagonists...
Evaluation of lercanidipine in Paclitaxel-induced neuropathic pain model in rat: a preliminary study [0.03%]
乐卡尼啶在紫杉醇诱导的神经病理性疼痛大鼠模型中的评价：初步研究
Lekha Saha,Debasish Hota,Amitava Chakrabarti
Lekha Saha
Objective. To demonstrate the antinociceptive effect of lercanidipine in paclitaxel-induced neuropathy model in rat. Materials and Methods. A total of 30 rats were divided into five groups of six rats in each group as follows: Gr I: 0.9% Na...
Fibromyalgia as a disorder related to distress and its therapeutic implications [0.03%]
压力相关的疾病：纤维肌痛的诊断与治疗意义
Petra Schweinhardt,Mary-Ann Fitzcharles,Chad Boomershine et al.
Petra Schweinhardt et al.
Neuroticism in young women with fibromyalgia links to key clinical features [0.03%]
年轻女性神经质与纤维肌痛综合征的重要临床特征有关
Katrina Malin,Geoffrey Owen Littlejohn
Katrina Malin
Objective. We examined personality traits in young women with FM, in order to seek associations with key psychological processes and clinical symptoms. Methods. Twenty-seven women with FM and 29 age-matched female healthy controls [HC] comp...
Interspinous spacer implant in patients with lumbar spinal stenosis: preliminary results of a multicenter, randomized, controlled trial [0.03%]
腰椎管狭窄症患者的棘突间融合器植入物的多中心随机对照试验初步结果
Larry E Miller,Jon E Block
Larry E Miller
A prospective, randomized, controlled trial was conducted to compare clinical outcomes in patients treated with an investigational interspinous spacer (Superion) versus those treated with an FDA-approved spacer (X-STOP). One hundred sixty-s...
C Richard Chapman,Ruth Zaslansky,Gary W Donaldson et al.
C Richard Chapman et al.
Poorly controlled postoperative pain is a longstanding and costly problem in medicine. The purposes of this study were to characterize the acute pain trajectories over the first four postoperative days in 83 cardiac surgery patients with a ...