Associations of FTO and MC4R Variants with Obesity Traits in Indians and the Role of Rural/Urban Environment as a Possible Effect Modifier [0.03%]
FTO和MC4R基因多态性与印度人肥胖表型的相关性研究及其环境修饰效应的探索性分析
A E Taylor,M N Sandeep,C S Janipalli et al.
A E Taylor et al.
Few studies have investigated the association between genetic variation and obesity traits in Indian populations or the role of environmental factors as modifiers of these relationships. In the context of rapid urbanisation, resulting in si...
Poor Perception of Body Weight Category amongst the Overweight and Obese with Chronic Hepatitis C: A Target for Intervention [0.03%]
慢性丙型肝炎患者对体重类别认知较差：一个亟待解决的问题
Venessa Pattullo,Nour Alkazaz,Sanjeev Sockalingam et al.
Venessa Pattullo et al.
Obesity in chronic hepatitis C (CHC) is associated with adverse hepatic and metabolic outcomes. This prospective study evaluates the agreement between self-perceived body weight (BW) status and measured body mass index (BMI) category and fa...
Treatment of Comorbid Obesity and Major Depressive Disorder: A Prospective Pilot Study for their Combined Treatment [0.03%]
共病肥胖和重度抑郁症的治疗：联合治疗的前瞻性初步研究
Lucy F Faulconbridge,Thomas A Wadden,Robert I Berkowitz et al.
Lucy F Faulconbridge et al.
Background. Obese individuals who suffer from major depressive disorder are routinely screened out of weight loss trials. Treatments targeting obesity and depression concurrently have not been tested. Purpose. To test the short-term efficac...
Can Thrifty Gene(s) or Predictive Fetal Programming for Thriftiness Lead to Obesity? [0.03%]
节俭基因或胎儿期预测性节俭效应会导致肥胖吗？
Ulfat Baig,Prajakta Belsare,Milind Watve et al.
Ulfat Baig et al.
Obesity and related disorders are thought to have their roots in metabolic "thriftiness" that evolved to combat periodic starvation. The association of low birth weight with obesity in later life caused a shift in the concept from thrifty g...
Jianhua Zhao,Struan F A Grant
Jianhua Zhao
Obesity is a major health problem and an immense economic burden on the health care systems both in the United States and the rest of the world. The prevalence of obesity in children and adults in the United States has increased dramaticall...
Obesity and its relationship with occupational injury in the canadian workforce [0.03%]
职业肥胖与加拿大劳动力市场的工伤关系研究
Ian Janssen,Eric Bacon,William Pickett
Ian Janssen
Objectives. To examine associations between obesity and occupational injury. Methods. Participants consisted of a representative sample of 7,678 adult Canadian workers. Participants were placed into normal weight, overweight, and obese cate...
Measures of obesity associated with asthma diagnosis in ethnic minority children [0.03%]
与少数民族儿童哮喘诊断相关的肥胖测量指标
Nita Vangeepuram,Susan L Teitelbaum,Maida P Galvez et al.
Nita Vangeepuram et al.
Objective. The study objective was to examine relationships between different body size measurements and asthma in ethnic minority children. Methods. We used data from a community-based study of 505 children aged 6-to-8 years old to study t...
Studies of gene variants related to inflammation, oxidative stress, dyslipidemia, and obesity: implications for a nutrigenetic approach [0.03%]
与炎症、氧化应激、血脂异常和肥胖相关的基因变异研究：营养基因组学方法的意义
Maira Ladeia R Curti,Patrícia Jacob,Maria Carolina Borges et al.
Maira Ladeia R Curti et al.
Obesity is currently considered a serious public health issue due to its strong impact on health, economy, and quality of life. It is considered a chronic low-grade inflammation state and is directly involved in the genesis of metabolic dis...
Amir H Sam,Victoria Salem,Mohammad A Ghatei
Amir H Sam
Endocannabinoid antagonism as a treatment for obesity and the metabolic syndrome became a hugely anticipated area of pharmacology at the start of the century. The CB1 receptor antagonist Rimonabant entered the European mass market on the ba...
An Obesity Risk SNP (rs17782313) near the MC4R Gene Is Associated with Cerebrocortical Insulin Resistance in Humans [0.03%]
肥胖风险SNP（rs17782313）位点与MC4R基因附近的人脑皮质胰岛素抵抗相关性研究
Otto Tschritter,Axel Haupt,Hubert Preissl et al.
Otto Tschritter et al.
Activation of melanocortin-4 receptor (MC4R) by insulin sensitive neurons is a central mechanism in body weight regulation, and genetic variants in the MC4R gene (e.g., rs17782313) are associated with obesity. By using magnetoencephalograph...