Determinants Associated With Obesity in Children of Low Socioeconomic Status Families: A Narrative Review [0.03%]
与低社会经济状态家庭儿童肥胖相关的决定因素：综述文章
Zeena Harakeh,Wilma Otten,Pepijn van Empelen
Zeena Harakeh
Children of families with low socioeconomic status (SES) are at higher risk for obesity and obesity-related lifestyle behaviors, i.e., unhealthy eating and low physical activity. This review aims to identify changeable determinants of obesi...
MRI-Based Genetic Studies Reveal Specific Genetic Variants and Disease Risks Associated With Fat Distribution Across Anatomical Sites [0.03%]
基于磁共振成像的基因研究揭示了与解剖部位脂肪分布相关的特定遗传变异和疾病风险
Altayeb Ahmed,Madeleine Cule,Afreen Naz et al.
Altayeb Ahmed et al.
Objective: To investigate the genetic determinants of fat distribution across anatomical sites and their implications for health outcomes. Methods: We analyzed neck-to-knee MRI data from the UK Biobank (n = 37,589) to measure fat at various...
Weight Loss Efficacy of Tirzepatide Compared to Placebo or GLP-1 Receptor Agonists in Adults With Obesity or Overweight: A Meta-Analysis of Randomized Controlled Trials With ≥ 20 Weeks Treatment Duration [0.03%]
司美格鲁肽与安慰剂或GLP-1受体激动剂相比在超重和肥胖成人中的减重效果：≥20周治疗的随机对照试验 meta 分析
Alhussain Khawaji,Abdulaziz A Jaly,Hanan A Bakri et al.
Alhussain Khawaji et al.
Introduction: Tirzepatide, a dual glucose-dependent insulinotropic peptide (GIP) and glucagon-like Peptide 1 (GLP-1) analogue, is a novel medication with comparable pharmacological characteristics and has demonstrated promising weight reduc...
Meta-Analysis
Journal of obesity. 2025 Jul 24:2025:3442754. DOI:10.1155/jobe/3442754 2025
Rita Khusainova,Ildar Minniakhmetov,Olga Vasyukova et al.
Rita Khusainova et al.
Obesity is a chronic metabolic disease characterized by excessive accumulation or uneven distribution of fat in the body, which poses a serious threat to health. Obesity significantly increases the risk of developing сonditions such as typ...
Calcium/Calmodulin-Dependent Protein Kinase II Inhibitors Mitigate High-Fat Diet-Induced Obesity in Mice [0.03%]
钙/钙调素依赖性蛋白激酶II抑制剂可减轻小鼠高脂饮食引起的肥胖症状
Naoyuki Kawao,Ryosuke Satoh,Yuya Mizukami et al.
Naoyuki Kawao et al.
Calcium signaling contributes to obesity and its related disorders, such as diabetes. We herein investigated the effects of calcium/calmodulin-dependent protein kinase II (CaMKII) inhibitors on diet-induced obesity in mice. In mice fed a hi...
Association of Genetic, Environmental, and Nutritional Factors With Metabolic Phenotypes of Obesity: A Scoping Review [0.03%]
肥胖代谢表型的遗传、环境和营养因素的相关性：一项范围回顾研究
Haniyeh Danesh Doost,Milad Nasiri Jounaghani,Roya Riahi et al.
Haniyeh Danesh Doost et al.
Background: There are inconsistent findings regarding the different metabolic phenotypes of obesity and associated risk factors. This scoping review aims to provide a comprehensive summary of the literature that has evaluated the relationsh...
Genomic Exploration of Nonalcoholic Fatty Liver Disease: Insights From Gene Expression and Variation in Morbidly Obese Individuals [0.03%]
基因型和表达型对非酒精性脂肪肝病的预测价值研究：来自极端肥胖个体的证据
Tamadher Abbas Rafaa,Safa Abbas Khudhair,Zahraa Yassen Mohammed et al.
Tamadher Abbas Rafaa et al.
Nonalcoholic fatty liver disease (NAFLD) is a common liver condition resulting from metabolic syndrome characterized by fat accumulation in the liver. It is often associated with obesity and diabetes, contributing to hepatic steatosis in li...
A Complex Network of Obesity-Risk Genes Revealed by Systematic Bioinformatics and Single-Cell Transcriptomic Analyses [0.03%]
系统生物信息学和单细胞转录组分析揭示肥胖易感基因的复杂网络
Yuenan Liu,Haolin Yuan,Junhui Hu et al.
Yuenan Liu et al.
The development of obesity is closely linked to genetic factors. Despite the identification of numerous genes associated with an increased risk of obesity in humans, a comprehensive understanding of their biological roles has not been achie...
Laparoscopic One Anastomosis Gastric Bypass as a Revisional Procedure After Failed Vertical Banded Gastroplasty: Our Center Experience [0.03%]
腹腔镜一次吻合胃旁路手术作为垂直束带胃成形术失败后的修正手术：我们中心的体会
Hosam Elghadban,Ashraf Shoma,Emad Abdallah et al.
Hosam Elghadban et al.
Background: Vertical banded gastroplasty (VBG) was historically a popular restrictive bariatric procedure, but long-term failure rates due to weight regain, stenosis, and gastroesophageal reflux have necessitated revisional interventions. O...
Comparative Analysis of Diabetic Ketoacidosis in Adults With Type 1 and Type 2 Diabetes Mellitus: Insights From a Saudi Arabian Cohort [0.03%]
沙特阿拉伯队列成人1型和2型糖尿病患者糖尿病酮症酸中毒的比较分析：来自Saudi Arabian队列的启示
Sadiq A Alali,Saqib A Ghulam,Khlood A Bukhamsin et al.
Sadiq A Alali et al.
Background: Diabetic ketoacidosis (DKA) is a life-threatening complication commonly seen in Type 1 diabetes mellitus (T1DM) but also affects Type 2 diabetes mellitus (T2DM). Objectives: To compare the clinical presentation, biochemical para...
Comparative Study
Journal of obesity. 2025 Mar 26:2025:3964619. DOI:10.1155/jobe/3964619 2025