Genomic research to identify novel pathways in the development of abdominal aortic aneurysm [0.03%]
基因组研究发现腹主动脉瘤发病的新机制路径
Seamus C Harrison,Anastasia Z Kalea,Michael V Holmes et al.
Seamus C Harrison et al.
Abdominal aortic aneurysm (AAA) is a common disease with a large heritable component. There is a need to improve our understanding of AAA pathogenesis in order to develop novel treatment paradigms. Genomewide association studies have revolu...
Kristin Veighey,Raymond J Macallister
Kristin Veighey
Ischemia-reperfusion injury is a composite of damage accumulated during reduced perfusion of an organ or tissue and the additional insult sustained during reperfusion. Such injury occurs in a wide variety of clinically important syndromes, ...
Duc Thang Vu,Eliana C Martinez,Theo Kofidis
Duc Thang Vu
Myocardial infarction is the leading cause of death in developed countries. Cardiac cell therapy has been introduced to clinical trials for more than ten years but its results are still controversial. Tissue engineering has addressed some l...
Haemodynamic monitoring using echocardiography in the critically ill: a review [0.03%]
重症患者超声心动图血流动力学监测进展及展望——系统综述
Michelle S Chew
Michelle S Chew
Physicians caring for the critically ill are now expected to acquire competence in echocardiography. It has become an indispensable diagnostic and monitoring tool in acute care settings where it is generally accepted to have therapeutic imp...
Increased atherothrombotic burden in patients with diabetes mellitus and acute coronary syndrome: a review of antiplatelet therapy [0.03%]
糖尿病患者的动脉粥样血栓负担加重：抗血小板治疗的综述分析
Karthik Balasubramaniam,Girish N Viswanathan,Sally M Marshall et al.
Karthik Balasubramaniam et al.
Patients with diabetes mellitus presenting with acute coronary syndrome have a higher risk of cardiovascular complications and recurrent ischemic events when compared to nondiabetic counterparts. Different mechanisms including endothelial d...
Oxygen Kinetics and Heart Rate Response during Early Recovery from Exercise in Patients with Heart Failure [0.03%]
心力衰竭患者运动早期恢复期氧动力学和心率的改变
Charalampos D Kriatselis,Sotirios Nedios,Sebastian Kelle et al.
Charalampos D Kriatselis et al.
Background. The purpose of this study was to assess the post-exercise O(2) uptake and heart rate response in patients with heart failure (HF) in comparison to healthy individuals. Methods and Results. Exercise testing of all subjects was co...
Novel Neurovascular Protective Agents: Effects of INV-155, INV-157, INV-159, and INV-161 versus Lipoic Acid and Captopril in a Rat Stroke Model [0.03%]
新型神经血管保护剂：INV-155、INV-157、INV-159和INV-161与左卡尼汀和卡托普利对大鼠卒中模型的作用效果研究
Barry J Connell,Bobby V Khan,Desikan Rajagopal et al.
Barry J Connell et al.
Background. Lipoic acid (LA), which has significant antioxidant properties, may also function as a potent neuroprotectant. The synthetic compounds INV-155, INV-157, INV-159, and INV-161 are physiochemical combinations of lipoic acid and cap...
Martin Thoenes,Peter Bramlage,Sam Zhong et al.
Martin Thoenes et al.
Background. We investigated the association between blood pressure control and common cardiometabolic risk factors from a global and regional perspective. Methods. In the present analysis of a large cross-sectional i-SEARCH study, 17.092 ou...
Alexander Hirsch,Robin Nijveldt,Igor Klem
Alexander Hirsch
Christina Chrysohoou,Christodoulos Stefanadis,Christos Pitsavos et al.
Christina Chrysohoou et al.