Saeid Golbidi,Ismail Laher
Saeid Golbidi
There are alarming increases in the incidence of obesity, insulin resistance, type II diabetes, and cardiovascular disease. The risk of these diseases is significantly reduced by appropriate lifestyle modifications such as increased physica...
Intracardiac Echocardiography during Catheter-Based Ablation of Atrial Fibrillation [0.03%]
导管消融房颤的腔内超声应用
Jürgen Biermann,Christoph Bode,Stefan Asbach
Jürgen Biermann
Accurate delineation of the variable left atrial anatomy is of utmost importance during anatomically based ablation procedures for atrial fibrillation targeting the pulmonary veins and possibly other structures of the atria. Intracardiac ec...
Pathophysiological implications of different bicuspid aortic valve configurations [0.03%]
不同类型的双叶主动脉瓣的病理生理意义
F A Kari,F Beyersdorf,M Siepe
F A Kari
There are numerous types of bicuspid aortic valve (BAV) configurations. Recent findings suggest that various BAV types represent different pathophysiological substrates on the aortic media level. Data imply that the BAV type is probably not...
Ify Mordi,Nikolaos Tzemos
Ify Mordi
Bicuspid aortic valve is the commonest congenital cardiac abnormality in the general population. This paper article will discuss our current knowledge of the anatomy, pathophysiology, genetics, and clinical aspects of bicuspid aortic valve ...
Diana Lindner,Moritz Hilbrandt,Katharina Marggraf et al.
Diana Lindner et al.
The transcription factor signal transducer and activator of transcription 3 (STAT3) is an important mediator of the inflammatory process. We investigated the role of STAT3 in viral myocarditis and its possible role in the development to dil...
Non-pharmacological therapy for atrial fibrillation: managing the left atrial appendage [0.03%]
心房颤动的非药物治疗：左心耳管理策略
Sushil Allen Luis,Damian Roper,Alexander Incani et al.
Sushil Allen Luis et al.
The prevalence of atrial fibrillation (AF) is increasing in parallel with an ageing population leading to increased morbidity and mortality. The most feared complication of AF is stroke, with the arrhythmia being responsible for up to 20% o...
Targeting the ACE2 and Apelin Pathways Are Novel Therapies for Heart Failure: Opportunities and Challenges [0.03%]
针对心力衰竭治疗的ACE2和Apelin通路：机遇与挑战
Seyyed M R Kazemi-Bajestani,Vaibhav B Patel,Wang Wang et al.
Seyyed M R Kazemi-Bajestani et al.
Angiotensin-converting enzyme 2 (ACE2)/Ang II/Ang 1-7 and the apelin/APJ are two important peptide systems which exert diverse effects on the cardiovascular system. ACE2 is a key negative regulator of the renin-angiotensin system (RAS) wher...
Association of Self-Reported Weight Change and Quality of Life, and Exercise and Weight Management Behaviors Among Adults with Type 2 Diabetes Mellitus: The SHIELD Study [0.03%]
糖尿病患者体重变化和生命质量及其与体育锻炼和体重管理行为之间关系的横断面调查（SHIELD研究）
Susan Grandy,Kathleen M Fox,Debbra D Bazata
Susan Grandy
Purpose. This study examined the association between self-reported weight change and quality of life, and exercise and weight management behaviors among individuals with type 2 diabetes mellitus (T2DM). Methods. In the US SHIELD study, resp...
Diverse spectrum of presentation of coronary slow flow phenomenon: a concise review of the literature [0.03%]
冠状动脉慢血流现象的临床表现多样性：文献综述
Muhammad A Chaudhry,Marcus Smith,Elias B Hanna et al.
Muhammad A Chaudhry et al.
The coronary slow flow phenomenon (CSFP) is a disease entity characterized by slow progression of angiographic contrast in the coronary arteries in the absence of stenosis in the epicardial vessels. CSFP has a diverse presentation from mild...
Targeted In Situ Gene Correction of Dysfunctional APOE Alleles to Produce Atheroprotective Plasma ApoE3 Protein [0.03%]
靶向原位基因修复功能异常的APOE等位基因以产生抗动脉粥样硬化的ApoE3蛋白
Ioannis Papaioannou,J Paul Simons,James S Owen
Ioannis Papaioannou
Cardiovascular disease is the leading worldwide cause of death. Apolipoprotein E (ApoE) is a 34-kDa circulating glycoprotein, secreted by the liver and macrophages with pleiotropic antiatherogenic functions and hence a candidate to treat hy...