Trypanosoma cruzi Coexpressing Ornithine Decarboxylase and Green Fluorescence Proteins as a Tool to Study the Role of Polyamines in Chagas Disease Pathology [0.03%]
用于研究泛素在查加斯病病理中的作用的共表达鸟氨酸脱羧酶和绿色荧光蛋白的克氏锥虫系体外细胞模型体系
Jeremías José Barclay,Luciano Gastón Morosi,María Cristina Vanrell et al.
Jeremías José Barclay et al.
Polyamines are essential for Trypanosoma cruzi, the causative agent of Chagas disease. As T. cruzi behaves as a natural auxotrophic organism, it relies on host polyamines biosynthesis. In this paper we obtained a double-transfected T. cruzi...
Interaction between Calcineurin and Ca/Calmodulin Kinase-II in Modulating Cellular Functions [0.03%]
钙调神经磷酸酶与钙/calmodulin激酶II在调节细胞功能中的相互作用
Manabu Kubokawa,Kazuyoshi Nakamura,You Komagiri
Manabu Kubokawa
Roles of calcineurin (CaN), a Ca(2+)/calmodulin- (CaM-) dependent protein phosphatase, and Ca(2+)/CaM-dependent protein kinase-II (CaMKII) in modulating K(+) channel activity and the intracellular Ca(2+) concentration ([Ca(2+)](i)) have bee...
Bryan R Crable,Caroline M Plugge,Michael J McInerney et al.
Bryan R Crable et al.
Biomethanation is a mature technology for fuel production. Fourth generation biofuels research will focus on sequestering CO(2) and providing carbon-neutral or carbon-negative strategies to cope with dwindling fossil fuel supplies and envir...
Different Effects of Mg and Zn on the Two Sites for Alkylammonium Compounds in Pseudomonas aeruginosa Phosphorylcholine Phosphatase [0.03%]
Mg和Zn对绿脓杆菌磷脂酰胆碱磷酸酶的两种季铵化合物作用位点的不同影响
Lisandro Horacio Otero,Paola Rita Beassoni,Cristhian Boetsch et al.
Lisandro Horacio Otero et al.
Pseudomonas aeruginosa phosphorylcholine phosphatase (PchP) catalyzes the hydrolysis of phosphorylcholine (Pcho), is activated by Mg(2+) or Zn(2+), and is inhibited by high concentrations of substrate. This study has shown that PchP contain...
Chemistry based on renewable raw materials: perspectives for a sugar cane-based biorefinery [0.03%]
基于可再生原料的化学：甘蔗生物精炼厂的发展前景
Murillo Villela Filho,Carlos Araujo,Alfredo Bonfá et al.
Murillo Villela Filho et al.
Carbohydrates are nowadays a very competitive feedstock for the chemical industry because their availability is compatible with world-scale chemical production and their price, based on the carbon content, is comparable to that of petrochem...
Evaluation of Chlorella (Chlorophyta) as Source of Fermentable Sugars via Cell Wall Enzymatic Hydrolysis [0.03%]
微藻细胞壁酶解获得发酵底物研究
Marcoaurélio Almenara Rodrigues,Elba Pinto da Silva Bon
Marcoaurélio Almenara Rodrigues
The cell wall of Chlorella is composed of up to 80% carbohydrates including cellulose. In this study, Chlorella homosphaera and Chlorella zofingiensis were evaluated as source of fermentable sugars via their cell wall enzymatic degradation....
Inhibitory effect of phthalic Acid on tyrosinase: the mixed-type inhibition and docking simulations [0.03%]
邻苯二甲酸抑制酪氨酸酶的混合型抑制作用及分子对接模拟研究
Shang-Jun Yin,Yue-Xiu Si,Guo-Ying Qian
Shang-Jun Yin
Tyrosinase inhibition studies are needed due to the medicinal applications such as hyperpigmentation. For probing effective inhibitors of tyrosinase, a combination of computational prediction and enzymatic assay via kinetics was important. ...
Identification of a Functional Type IA Topoisomerase, LdTopIIIβ, from Kinetoplastid Parasite Leishmania donovani [0.03%]
利什曼原生动物IA型拓扑异构酶LdTopIIIβ的鉴定研究
Bijoylaxmi Banerjee,Nilkantha Sen,Hemanta K Majumder
Bijoylaxmi Banerjee
DNA topoisomerases of kinetoplastids represent a family of DNA processing enzymes that essentially solve the topological problems not only in nuclear DNA but also in kinetoplast DNA. We have, for the first time, identified a Leishmania dono...
Enhancement of Cellulase Activity from a New Strain of Bacillus subtilis by Medium Optimization and Analysis with Various Cellulosic Substrates [0.03%]
通过优化培养基和使用各种纤维素质底物分析从芽孢杆菌新菌株中提取的纤维素酶活性增强
Deepmoni Deka,P Bhargavi,Ashish Sharma et al.
Deepmoni Deka et al.
The cellulase activity of Bacillus subtilis AS3 was enhanced by optimizing the medium composition by statistical methods. The enzyme activity with unoptimised medium with carboxymethylcellulose (CMC) was 0.07 U/mL and that was significantly...
The Involvement of Glutamate Metabolism in the Resistance to Thermal, Nutritional, and Oxidative Stress in Trypanosoma cruzi [0.03%]
谷氨酸代谢参与热、营养和氧化应激下克氏锥虫的抵抗作用
Anahí Magdaleno,Brian Suárez Mantilla,Sandra C Rocha et al.
Anahí Magdaleno et al.
The inhibition of some glutamate metabolic pathways could lead to diminished parasite survival. In this study, the effects of L-methionine sulfoximine (MS), DL-methionine sulfone (MSO), and DL-methionine sulfoxide (MSE), three glutamate ana...