Sustainable Cultivation and Functional Bioactive Compounds of Auricularia Mushrooms: Advances, Challenges, and Future Prospects [0.03%]
银耳的可持续栽培及其功能性生物活性化合物的研究进展、挑战与前景展望
Miao Liu,Wenxin Jiang,Kai Huang et al.
Miao Liu et al.
The genus Auricularia, and specifically the species A. auricula, is a globally significant edible fungus with a long history of cultivation and notable nutritional and medicinal properties. This review systematically examines the taxonomic ...
Transcriptomics and Metabolomics Reveal Mechanisms Underlying the Adaptation of Lamiophlomis rotata to High Altitudes [0.03%]
转录组和代谢组揭示了Lamiophlomis rotata高海拔适应机制
Yunzhang Xu,Sangjie Jiancuo,Xiao Luo et al.
Yunzhang Xu et al.
Lamiophlomis rotata (Benth.) Kudo is a typical alpine medicinal plant. However, the mechanism underlying its adaptation to high altitudes remains incompletely understood. In this study, we integrated transcriptome and metabolome analyses. S...
Combined Effects of Diazoxide and Moderate-Intensity Exercise on the Restoration of Redox Balance Post-Fatigue in Fast- and Slow-Twitch Skeletal Muscles of Hypertensive Rats [0.03%]
二氮氧化物与中等强度运动对高血压大鼠疲劳后快慢肌红氧平衡恢复的联合作用
Estefanía Bravo-Sánchez,César J Nolasco-Ruiz,Sarai Sánchez-Duarte et al.
Estefanía Bravo-Sánchez et al.
Muscle fatigue, defined as a decline in force generation, is closely linked to redox imbalance-a condition exacerbated by oxidative stress in hypertension. This study investigated the effects of diazoxide administration and moderate-intensi...
Characterising PMP22-Proximal Partners in a Schwann Cell Model of Charcot-Marie-Tooth Disease Type1A [0.03%]
一种雪旺细胞模型的Charcot-Marie-Tooth 1A型疾病的PMP22邻近蛋白的表征研究
Ian Holt,Nicholas Emery,Monte A Gates et al.
Ian Holt et al.
Charcot-Marie-Tooth disease type 1A (CMT1A) is a hereditary condition caused by the duplication of the PMP22 gene. Overexpression of peripheral myelin protein 22 in Schwann cells leads to myelin sheath defects and axonal loss. We have produ...
Glycogen Synthase Kinase 3 Is Essential for Intestinal Cell Niche and Digestive Function [0.03%]
糖原合成酶激酶3对肠细胞生态位和消化功能是必不可少的
Minggang Yang,Xiaohui Li,Jiajia Zhan et al.
Minggang Yang et al.
WNT/β-catenin signaling is essential for intestinal stem cell development and self-renewal, while its dysregulation can drive tumorigenesis. GSK3, a key negative regulator of β-catenin, in intestinal homeostasis remains incompletely under...
Relationship Between Sperm Parameters and Indices of Chromatin Condensation and DNA Fragmentation in Semen [0.03%]
精液参数与染色质浓缩和DNA碎片指数之间的关系
Othmane Adli,Noureddine Louanjli,Rachid Aboutaieb
Othmane Adli
Infertility is a major health problem affecting about 15% of couples worldwide. Male etiology is found in almost one-third of cases. This study identified the nature of the relationship between sperm DNA fragmentation (SDF), sperm chromatin...
Phylogeographic Insights into Pipistrellus Species from Türkiye: Diversity, Divergence, and Regional Lineage Structure [0.03%]
土耳其管鼻蝠物种的谱系地理学见解：多样性、分化和区域谱系结构
Emin Seyfi,Şafak Bulut,Gül Olgun Karacan
Emin Seyfi
This study investigates the phylogenetic relationships, genetic diversity, and biogeographic structure of Pipistrellus species in Türkiye using mitochondrial cytochrome b (Cytb) sequences from 156 specimens collected across 26 localities. ...
Pan-Mitogenome Construction, Intraspecific Variation, and Adaptive Evolution of the Plant Pathogenic Fungus Claviceps purpurea [0.03%]
麦角菌属放线孢霉的泛基因组构建、种内变异和适应性进化分析
Mingliang Ding,Rui Hu,Jinlong Jia et al.
Mingliang Ding et al.
Claviceps purpurea is a specialized phytopathogenic fungus that infects grasses and produces pharmacologically active compounds, attracting considerable interest in genomic research. In this study, we assembled and annotated the complete mi...
PLIN5 Promotes Lipid Reconstitution in Goat Intramuscular Fat via the PPARγ Signaling Pathway [0.03%]
PLIN5通过PPARγ信号通路促进 goat 灌肌脂肪脂质重构
Yuhan Dai,Yuling Yang,Haiyang Li et al.
Yuhan Dai et al.
Intramuscular fat (IMF) content is an important factor of goat meat quality, which is related to the proliferation and differentiation of intramuscular preadipocytes. Perilipin 5 (PLIN5) is a lipid droplet-associated protein; however, the s...
Metabolome and Metagenome Signatures Underlying the Differential Resistance of Percocypris pingi, Crucian Carp, and Yellow Catfish to Ichthyophthirius multifiliis Infection [0.03%]
泥鳅、鲫鱼和黄颡鱼抗多子小瓜虫病的代谢组和元基因组标志物研究
Yi Liu,Jiang Xie,Yang He et al.
Yi Liu et al.
Ichthyophthirius multifiliis poses a significant threat to global aquaculture, yet some fish species exhibit remarkable resistance. This study employed a combined LC-MS-based metabolomics and 16S rRNA gene sequencing approach to investigate...