Assessment of Freshwater Unionidae Using Environmental DNA Metabarcoding in Lentic Ecosystems: Implications for Spatial Sampling Strategies [0.03%]
基于环境DNA宏条形码的湖泊生态系统中淡水无齿蚌监测及其空间采样策略评估
Keonhee Kim,Junhee Kwon,Kyujin Kim et al.
Keonhee Kim et al.
Environmental DNA (eDNA) metabarcoding has become a powerful, non-invasive method for detecting aquatic organisms. However, optimal sampling strategies for benthic taxa in lentic ecosystems remain unclear. This study evaluated the effective...
Effects of Mobile Sheepfold and Supplementary Feeding on Growth Performance, Serum Indicators and Gut Microbiota in Natural Grazing Gangba Sheep [0.03%]
移动羊圈和补饲对天然放牧刚巴绵羊生长性能、血清指标及肠道微生物的影响
Yining Xie,Junhong Wang,Zhaohan Zhan et al.
Yining Xie et al.
High-altitude grazing animals are continuously exposed to strong wind and low temperature, which challenge physiological homeostasis and energy metabolism. Improving living conditions and nutritional supplementation are two commonly used st...
A Porcine-Isolated Mycobacterium bovis Strain Exhibits Hypervirulence in a Murine Pulmonary Tuberculosis Model [0.03%]
一株猪来源的Mycobacterium bovis在小鼠肺结核模型中表现出高毒力性质
María Ximena Cuerda,María Alejandra Colombatti,Luisa Berná et al.
María Ximena Cuerda et al.
Mycobacterium bovis is the causative agent of tuberculosis (TB) infecting a wide range of animal hosts, including humans. Domestic pigs (Sus scrofa domestica) are susceptible to different mycobacteria, particularly species within the Mycoba...
Generative AI Accelerates Genotype-Phenotype Characterization of a 1600-Case Leigh Syndrome Virtual Cohort from Published Literature [0.03%]
生成式AI加速莱氏综合征虚拟队列（取材于已发表文献的1600个案例）的基因型表型特征分析
Lishuang Shen
Lishuang Shen
Leigh Syndrome Spectrum (LSS) is a rare and heterogeneous disease continuum with most published cohorts in small sizes that limit the statistical power. Large-scale meta-analyses with published case-level clinical data extracted from the li...
Lysolecithin Attenuates LPS-Induced Acute Liver Injury in Weaned Piglets by Inhibiting M1 Macrophage Polarization via the mTOR-Glycolysis Pathway [0.03%]
溶血卵磷脂通过mTOR糖酵解通路抑制M1型巨噬细胞极化缓解断奶仔猪内毒素性急性肝损伤
Kui Shu,Juan Xiong,Xianfeng Xu et al.
Kui Shu et al.
Macrophage polarization is widely recognized as a pivotal role in the maintenance of liver homeostasis. Lysolecithin (LPC) has previously been associated with hepatoprotective effect. This study aimed to determine whether LPC protected agai...
Comparative Analysis of Morphological, Molecular, and Physicochemical Markers to Evaluate Trollius ledebouri Rchb. as a Potential Alternative Source to Trollius chinensis Bunge for High-Quality Flos Trollii Supplements [0.03%]
形态学、分子和理化标记比较分析评估番红花 Trollius ledebouri Rchb. 作为优质唐松草药材的潜在替代来源
Lianqing He,Panpan Wang,Zhen Wang et al.
Lianqing He et al.
Trollius chinensis Bunge (TCB), a perennial Ranunculaceae herb, produces Flos Trollii-dried flowers with medicinal properties including heat clearing, detoxification, and relieving oral/throat discomfort, eye pain, and cold-induced fever. T...
Effects of High-Flow-Velocity Stress on Energy Metabolism and Transcription Level of Triplophysa orientalis [0.03%]
高流速流水对东方薄鳅能量代谢及基因表达水平的影响
Xin Gao,Hui Wan,Yuxuan Jiang et al.
Xin Gao et al.
River channel development and hydraulic engineering alter natural flow-velocity patterns, subjecting Triplophysa orientalis to heightened hydrodynamic stress and energy expenditure in high-flow-velocity habitats. Regulating the molecular re...
Methyl-Lysine-Dependent Control of Protein Lifetime Through Lysine-Node Crosstalk and Reader-Coupled Degradation [0.03%]
赖氨酸交叉谈话和读码框耦联降解介导的甲基赖氨酸依赖性蛋白质寿命调控
Brad E Morrison
Brad E Morrison
The half-life of proteins is determined by the "information" carried within specific regions of the protein. Lysine methylation is an emerging post-translational modification that can act at the decision node. In contrast to the charge-neut...
The Impact of Significant Geographical Barriers on the Invasion Risk of Non-Native Aquatic Animals: A Case Study of the Qinling Mountains, China [0.03%]
青藏高原对非本土鱼类入侵风险的阻隔效应研究
Xin Wang,Chen Tian,Xiaoyu Jia et al.
Xin Wang et al.
Biological invasion is a major driver of biodiversity loss and ecosystem disruption, with non-native aquatic species threatening ecological integrity and economic stability. The Qinling Mountains, located in central China, serve as a crucia...
Integrated Quality Assessment and Metabolomic Analysis of Dezhou Donkey Meat During Extended Chilled Storage [0.03%]
驴肉在延长冷却储存期间的综合品质评定及代谢组学分析
Yanhao Zhao,Muhammad Zahoor Khan,Muhammad Saeed et al.
Yanhao Zhao et al.
This study aimed to elucidate the dynamic changes in meat quality attributes and metabolomic profiles of Dezhou donkey longissimus lumborum (LL) during extended chilled storage. Donkey longissimus lumborum (LL) muscles (n = 4) were vacuum-p...