Beyond BMI: Nutritional Recovery and Functional Implications of CFTR Modulators in Cystic Fibrosis [0.03%]
超越BMI:囊性纤维化跨膜传导调节器的作用及其在营养恢复和功能影响方面的意义
Giovanna Linguiti,Vanja Granberg,Giuseppina Leonetti et al.
Giovanna Linguiti et al.
Cystic fibrosis (CF) is a multisystem genetic disorder in which malnutrition has historically been a major determinant of disease severity. The advent of CFTR modulators has significantly altered the nutritional and functional profile of CF...
Microbial Differences in Rhizospheric and Ednophytic Microbiota in Healthy Chinese Yam Roots and Those Affected by Yam End Black Disease [0.03%]
健康与中国薯蓣受山药茎线根病菌感染植株根系微生物差异分析
Yuwei Liu,Fanli Zeng,Zhimin Hao et al.
Yuwei Liu et al.
Yam end black disease (YEBD) is a devastating soil-borne disease that severely compromises the yield of Chinese yam (Dioscorea opposita Thunb.). Despite its agricultural importance, the etiological agents and molecular mechanisms underlying...
Benefits of Sea Cucumber Viscera on Gut Microbiota and Their Implications for Health [0.03%]
海参内脏对肠道微生物组的影响及健康意义
Hao Zhong,Huange Zhang,Weiming Liu et al.
Hao Zhong et al.
Sea cucumber viscera, the primary by-product of processing, are generated in increasing quantities annually, leading to significant environmental pollution and resource wastage. Nevertheless, they are rich in nutrients and possess diverse b...
The Neuro-Bone Axis in Metastatic Progression: Innervation, Neuro-Immune-Osteoclast Crosstalk, and Therapeutic Opportunities [0.03%]
神经骨骼轴在转移进展中的作用:神经-免疫-破骨细胞交叉谈及其治疗机会
Mohamad Bakir,Alhomam Dabaliz,Mohammed Raddaoui et al.
Mohamad Bakir et al.
Bone metastases represent a major cause of morbidity in advanced cancers, yet the neural regulation of metastatic growth within bone remains largely unexplored. The skeletal system is richly innervated by sensory and sympathetic nerve fiber...
Comparative Analysis of Eye Traits and Visual Resolution Among Three Hatchery-Bred Giant Clams (Tridacna crocea, T. squamosa, T. maxima) [0.03%]
三种人工培育的大法螺(斑点大法螺、鳞大法螺、极大法螺)的眼部特征和视觉分辨率的比较分析
Wanjie Liu,Jun Li,Zhen Zhao et al.
Wanjie Liu et al.
Bivalves possess a diverse array of photoreceptive organs that are significant for their evolutionary success and systematic classification. Giant clams are the largest bivalve mollusks, with mantle tissue permanently extended in nature to ...
A Proinflammatory Psoriatic Microenvironment Has Early Effects on Keratinocyte Proliferation/Differentiation and Induces Ferroptosis in HaCaT Cells [0.03%]
促炎性银屑病微环境对角质细胞增殖/分化具有早期影响并在HaCaT细胞中诱导铁死亡
Federica Riva,Elena Gammella,Margherita Correnti et al.
Federica Riva et al.
Background: The interaction between keratinocytes and proinflammatory cytokines is essential in the development of psoriatic lesions. The synergism among these cytokines and their involvement in ferroptosis are not yet elucidated. This stud...
Insight into Genome-Wide Associations of Growth Trajectories Using a Hierarchical Non-Linear Mixed Model [0.03%]
基于层次非线性混合模型的生长轨迹全基因组关联研究的新视角
Ying Zhang,Liang Yang,Weiguo Cui et al.
Ying Zhang et al.
In applying a hierarchical mixed model to genome-wide association analysis (GWAS) of longitudinal data, dimensionality reduction through modeling repeated measurements improves both computational efficiency and statistical power. Legendre p...
Olfactory Disruption Restructures Collective Behavior and Increases Cohesive Group Dynamics [0.03%]
嗅觉干扰重塑集体行为并增加群体凝聚力
Kaihang Chen,Zoe Shteyn,Thomas Ring et al.
Kaihang Chen et al.
Olfaction plays a central role in mammalian social behavior, yet its contribution to group coordination remains poorly understood. Here, we show that olfactory impairment in adult C57BL/6J mice (Mus musculus) leads to the spontaneous emerge...
Community Structure and Soil Environmental Drivers of Rhizosphere and Root Endophytic Microbiota of Polygonum divaricatum in a Temperate Grassland [0.03%]
温度草原中Polygonum divaricatum根系和内生细菌群落结构及其土壤环境驱动因素分析
Yubo Ren,Bo Zhang,Hui Jin et al.
Yubo Ren et al.
Understanding the ecological drivers of plant-associated microbiota is essential for predicting grassland ecosystem resilience. This study aimed to characterize the community structure, functional potential, and soil environmental drivers o...
Landscape Features Shape Maternal Genetic Structure of Asian Elephants in Thailand: Insights from mtDNA [0.03%]
泰国亚洲象线粒体DNA研究揭示地貌特征影响母系遗传结构
Supansa Rerkdee,Worapong Singchat,Thitipong Panthum et al.
Supansa Rerkdee et al.
Landscape features often shape maternal genetic structure by influencing connectivity. In this study, habitat fragmentation, a major threat to the Asian elephant (Elephas maximus), was assessed through an integrated approach involving mitoc...