Unravelling the Genetic Architecture of Flowering in Common Vetch (Vicia sativa L.) Through Multi-Season QTL Mapping [0.03%]
基于多季QTL定位解析狭叶打碗花开花期遗传结构
Eva M Córdoba,Clara I González-Verdejo,Sergio G Atienza et al.
Eva M Córdoba et al.
Flowering time is a key adaptive trait in common vetch (Vicia sativa L.), influencing crop adaptation, yield potential, and forage quality. Despite its importance, the genetic basis of flowering in this species remains poorly understood. In...
Circulating Tumor DNA in Multiple Myeloma: Current Insights and Future Perspectives [0.03%]
多发性骨髓瘤中循环肿瘤DNA的现状及未来展望
Aleksandra Sretenovic,Marko Mitrovic,Nikola Vukosavljevic et al.
Aleksandra Sretenovic et al.
Circulating tumor DNA (ctDNA) has emerged as a promising minimally invasive biomarker in multiple myeloma (MM), providing dynamic insight into tumor burden, clonal evolution and molecular heterogeneity. Unlike conventional bone marrow-based...
Maternal Polystyrene Nanoplastic Exposure Impairs Cardiac Development in Mouse Offspring and Identifies Lactation as a Sensitive Window in Males [0.03%]
母体纳米级聚苯乙烯塑料暴露损害小鼠后代心脏发育并确定哺乳是男性的一个敏感窗口
Xiaorui Zhang,Yingguang Li,Xiaotao Zhang et al.
Xiaorui Zhang et al.
Maternal exposure to nanoplastics is a growing concern, but its effects on offspring cardiac development and the relative importance of prenatal and lactational exposure remain unclear. Pregnant C57BL/6J mice were orally exposed to 50 nm po...
Mitochondrial Distribution Patterns and Remodeling During In Vitro Maturation of Alpaca (Vicugna pacos) Oocytes [0.03%]
人工培养条件下羊驼(Vicugna pacos)卵母细胞的线粒体分布规律及重塑现象分析
Paula Quijano,Alejandra Ugarelli,José Sánchez et al.
Paula Quijano et al.
Mitochondrial distribution and activity are closely associated with cytoplasmic maturation and developmental competence in mammalian oocytes; however, limited information is available regarding these processes in Vicugna pacos. This study a...
Physicochemical and FTIR-ATR Spectroscopic Characterization of Lipid Deterioration in Raw Horse Mesenteric Fat Under Stress Storage Conditions [0.03%]
应力贮藏条件下马网油脂质氧化的理化及FTIR-ATR光谱特征分析
Moldir Nurseitova,Meruert Syzdyk,Xenia Dronova et al.
Moldir Nurseitova et al.
Horse mesenteric fat is a culturally significant and nutritionally valuable food product in Central Asia, yet the kinetics of its oxidative and hydrolytic deterioration under sub-optimal storage conditions remain poorly characterized. Raw m...
Evaluating Somatic Mutational Contamination in Large-Scale Germline Genomic Studies [0.03%]
评估大规模生殖系基因组研究中体细胞突变污染的方法
Xiangwen Ji,Xueke Bai,Guangda He et al.
Xiangwen Ji et al.
Large-scale genomic initiatives like the UK Biobank have revolutionized our understanding of human disease. These studies typically assume that blood-derived DNA faithfully reflects an individual's germline genome. However, this assumption ...
Specialized Pro-Resolving Mediators at the Ocular Surface: Biosynthesis, Mechanisms, and Therapeutic Potential [0.03%]
特异性的促解决介质在眼表:生物合成、机制及治疗潜力
Siddharth Gandhi,Arveen Shokravi,Sydney Buhrow et al.
Siddharth Gandhi et al.
Specialized pro-resolving mediators (SPMs) are endogenous lipid mediators that actively orchestrate the resolution of inflammation rather than relying solely on broad suppression of inflammatory signaling. At the ocular surface, lipoxins, r...
Recovery of Hindlimb Motor Function Is Accompanied by Lumbar Neural Remodeling After Complete Spinal Cord Transection in Neonatal Mice [0.03%]
新生小鼠完全脊髓横断后下肢运动功能恢复伴随腰段神经重塑
Wanxing Peng,Ran Li,Lulu Zhang et al.
Wanxing Peng et al.
Spinal cord injury often causes persistent neurological dysfunction, whereas the developing central nervous system retains greater plasticity. This study investigated whether spontaneous hindlimb motor recovery occurs after complete spinal ...
A Dendrimer-Based Multiple Antigenic Peptide (MAP) Approach for Dengue Vaccine Development: In Silico and In Vivo Insights on Safety and Effectiveness [0.03%]
基于树形聚合物的登革热疫苗开发的多抗原肽(MAP)方法:安全性和有效性的计算机模拟和体内研究见解
Amtul Wadood Wajeeha,Najam Us Sahar Sadaf Zaidi,Deeba Amraiz et al.
Amtul Wadood Wajeeha et al.
Dengue fever, a rapidly spreading mosquito-borne viral disease, poses a major global health issue, particularly in tropical and subtropical regions. The absence of a universally effective vaccine against all four dengue virus serotypes nece...
Constraint and Allometric Diversification in a Simplified Neck: Shape Evolution of the Atlas in Hyloidea (Anura) [0.03%]
简化颈肌条件下绳杆菌科(雨蛙亚目)奥氏椎体的几何及等比例多样化分析
Henrique Folly,Jéssica Fratani,Virginia Abdala et al.
Henrique Folly et al.
The anuran atlas represents one of the most structurally simplified cervical systems among tetrapods, consisting of a single vertebra that must simultaneously support the head, permit mobility, and withstand mechanical loads generated durin...