A multidisciplinary approach for people with HIV failing antiretroviral therapy in South Africa [0.03%]
在南非采用多学科方法治疗抗逆转录病毒药物疗效不佳的艾滋病患者
Parisha M Juta,Juan M Jansen van Vuuren,Kabamba J Mbaya
Parisha M Juta
Background: South Africa (SA) has the largest antiretroviral therapy (ART) programme worldwide. Multiple factors contribute to virological failure (VF), including poor adherence and viral resistance mutations. A multidisc...
The rollout of paediatric dolutegravir and virological outcomes among children living with HIV in Mozambique [0.03%]
莫桑比克儿童中儿科多替拉韦的推广及艾滋病病毒学结果
Ivete Meque,Nicole Herrera,Amâncio Nhangave et al.
Ivete Meque et al.
Background: In 2022, Mozambique introduced Dolutegravir 10mg (pDTG), as part of paediatric antiretroviral therapy for children weighing < 20 kg. Understanding real-world challenges during national rollout can strengthen h...
Knowledge and attitudes in the prevention of vertical transmission of HIV in referral hospitals [0.03%]
西藏大型综合性医院医务人员人类免疫缺陷病毒垂直传播预防知识和态度调查
Patience D Magugu,Melissa A Lawler,Kimesh L Naidoo
Patience D Magugu
Background: Prevention of HIV vertical transmission programmes (VTPs) in South Africa has decreased paediatric HIV. These programmes require integration in referral hospitals. ...
Exploring factors hindering the uptake of HIV pre-exposure prophylaxis by potential users in Namibia [0.03%]
探索艾滋病毒暴露前预防在纳米比亚潜在使用者中推广的障碍因素
Daniel O Ashipala
Daniel O Ashipala
Background: Pre-exposure prophylaxis (PrEP) is recommended for people who are at substantial risk of HIV infection, in conjunction with other HIV prevention tools and strategies. Unfortunately, the uptake of PrEP among po...
Lived experience of people with cryptococcal meningitis: A qualitative study [0.03%]
隐球菌性脑膜炎患者的个人经历：一项定性研究
Neo A Legare,Vanessa C Quan,Nelesh P Govender et al.
Neo A Legare et al.
Background: The high burden of cryptococcal meningitis (CM) among people living with HIV persists despite widespread access to antiretroviral therapy. Efforts to prevent CM among people living with HIV could be hindered b...
How paediatric HIV services weathered the COVID-19 storm in Tshwane District, South Africa [0.03%]
南非特斯瓦内地区儿科HIV服务应对新冠肺炎疫情的情况
Michael Christie,Ahmad Haeri Mazanderani,Gayle Sherman et al.
Michael Christie et al.
Background: The coronavirus disease 2019 (COVID-19) pandemic disrupted paediatric HIV services across South Africa. Shortly before COVID-19, updated national HIV guidelines were released. ...
Virologic outcomes with tenofovir-lamivudine-dolutegravir in adults failing PI-based second-line ART [0.03%]
在二线抗逆转录病毒治疗失败的成年人群中使用替诺福韦-拉米夫定-多替拉韦的 virologic结局效果
Ying Zhao,Jacqueline Voget,Isaac Singini et al.
Ying Zhao et al.
Background: In South African antiretroviral guidelines, selected patients failing second-line protease inhibitor (PI)-based therapy qualify for genotypic resistance testing - those with PI resistance receive darunavir-bas...
Effect of dolutegravir on ferritin, iron, and C-reactive protein among people living with HIV and co-infections [0.03%]
多替拉韦对艾滋病病毒感染者及合并感染者血清铁蛋白、铁和C反应蛋白的影响
Bridget Kamurai,Raylton P Chikwati,Donald Vhanda et al.
Bridget Kamurai et al.
Background: Dolutegravir-based antiretroviral therapy (ART) is currently recommended as the preferred first-line ART in many resource-limited settings. However, little is known about the clinical experience of dolutegravi...
Southern African HIV Clinicians Society Guideline for the clinical management of syphilis [0.03%]
南非艾滋病临床医师协会梅毒临床管理指南
Remco P H Peters,Jeremy S Nel,Eitzaz Sadiq et al.
Remco P H Peters et al.
Syphilis, 'the great imitator', caused by Treponema pallidum infection, remains a complex and multifaceted disease with a rich history of clinical diversity. This guideline aims to be a comprehensive guide for healthcare workers in Southern...
Trends in body mass index in the pre-dolutegravir period in South Africa [0.03%]
南非在开始使用多替拉韦之前体重指数的变化趋势
Florian van Ginkel,Roos E Barth,Hugo Tempelman et al.
Florian van Ginkel et al.
Background: Antiretroviral therapy (ART) is associated with weight gain, but this has been shown to be more marked with dolutegravir and other integrase strand transfer inhibitors. ...