Common Pitfalls in Ewing Sarcoma and Desmoplastic Small Round Cell Tumor Diagnosis Seen in a Study of 115 Cases [0.03%]
伊 wing肉瘤和desmoplastic小圆细胞肿瘤诊断研究中常见的陷阱(研究对象为115例病患)
Nikolaos A Trikalinos,John S A Chrisinger,Brian A Van Tine
Nikolaos A Trikalinos
Ewing sarcoma (ES), "Ewing-like sarcoma" (ELS) and desmoplastic small round cell tumors (DSRCT) can masquerade as other tumor types, particularly neuroendocrine neoplasms and receive inappropriate treatment. We retrieved 115 cases of ES, EL...
Epidemiology of Melanoma [0.03%]
黑色素瘤的流行病学研究
Kalyan Saginala,Adam Barsouk,John Sukumar Aluru et al.
Kalyan Saginala et al.
Melanoma accounts for 1.7% of global cancer diagnoses and is the fifth most common cancer in the US. Melanoma incidence is rising in developed, predominantly fair-skinned countries, growing over 320% in the US since 1975. However, US mortal...
Universal Access to Advanced Imaging and Healthcare Protection: UHC and Diagnostic Imaging [0.03%]
高级影像和医疗保健防护的普遍访问：全民健康覆盖与诊断影像
Pietro Cappabianca,Gaetano Maria Russo,Umberto Atripaldi et al.
Pietro Cappabianca et al.
Universal Health Coverage (UHC) is a set of principles adopted by the World Health Organization (WHO) aimed to guarantee access to primary care for the entire world population through a range of essential health services without neglecting ...
Critical Role of Caveolin-1 Loss/Dysfunction in Pulmonary Hypertension [0.03%]
肺高血压中外泌蛋白-1丧失/功能障碍的关键作用
Rajamma Mathew
Rajamma Mathew
Pulmonary hypertension (PH) is a rare disease with a high morbidity and mortality rate. A number of systemic diseases and genetic mutations are known to lead to PH. The main features of PH are altered vascular relaxation responses and the a...
Clinically Distinct Subtypes of Acute Kidney Injury on Hospital Admission Identified by Machine Learning Consensus Clustering [0.03%]
住院时通过机器学习共识聚类识别的急性肾损伤临床不同亚型
Charat Thongprayoon,Pradeep Vaitla,Voravech Nissaisorakarn et al.
Charat Thongprayoon et al.
Background: We aimed to cluster patients with acute kidney injury at hospital admission into clinically distinct subtypes using an unsupervised machine learning approach and assess the mortality risk among the distinct cl...
Christopher J LaRocca,Lily Lai,Rebecca A Nelson et al.
Christopher J LaRocca et al.
Despite the changing paradigms of melanoma treatment in recent years, there remains a relative paucity of data regarding subungual melanoma in the literature. From 2002-2018, 25 patients with subungual melanoma were surgically treated at ou...
Are We Paving the Way to Dig Out of the "Pandemic Hole"? A Narrative Review on SARS-CoV-2 Vaccination: From Animal Models to Human Immunization [0.03%]
从动物模型到人体免疫：关于SARS-CoV-2疫苗的叙事性综述：我们是否在为走出“大流行经济坑洞”铺平道路？
Giuseppe Tardiolo,Pina Brianti,Daniela Sapienza et al.
Giuseppe Tardiolo et al.
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new pathogen agent causing the coronavirus infectious disease (COVID-19). This novel virus originated the most challenging pandemic in this century, causing economic and ...
Experimental Models to Study Skin Wound Healing with a Focus on Angiogenesis [0.03%]
聚焦于血管生成的皮肤伤口愈合研究的实验模型
Eberhard Grambow,Heiko Sorg,Christian G G Sorg et al.
Eberhard Grambow et al.
A large number of models are now available for the investigation of skin wound healing. These can be used to study the processes that take place in a phase-specific manner under both physiological and pathological conditions. Most models fo...
Towards User-Oriented Recommendations for Local Therapy of Leg and Foot Ulcers-An Update of a S3-German Guideline [0.03%]
以用户为导向的下肢和足部溃疡局部治疗推荐意见——S3德国指南更新
Marion Burckhardt,Brigitte Nink-Grebe,Andreas Maier-Hasselmann
Marion Burckhardt
Background: The German S3- guideline on local therapy of leg ulcers and diabetic foot ulcers is in the process of being updated. Major goals are to improve the guidelines' applicability and to take steps towards a living ...
Effects of Rapamycin on Insulin Brain Endothelial Cell Binding and Blood-Brain Barrier Transport [0.03%]
雷帕霉素对胰岛素脑内皮细胞结合和血脑屏障转运的影响
Steven Nguyen,William A Banks,Elizabeth M Rhea
Steven Nguyen
Rapamycin is an exogenous compound that has been shown to improve cognition in Alzheimer's disease mouse models and can regulate pathways downstream of the insulin receptor signaling pathway. Insulin is also known to improve cognition in ro...