ICU Admission and Post-Discharge Mortality in COVID-19: Different Risk Factors Across Clinical Phases [0.03%]
COVID-19患者重症监护室收治及出院后死亡的风险因素：不同临床阶段的区别
Fernanda Leite,André Santos Silva,Sara Ferreira et al.
Fernanda Leite et al.
Background: Risk factors for severe COVID-19 and in-hospital mortality are well described, but it remains unclear whether the same factors predict mortality after hospital discharge. Distinguishing risk profiles across cl...
Observational Study
Medical sciences (Basel, Switzerland). 2026 May 14;14(2):255. DOI:10.3390/medsci14020255 2026
Loss of PTEN as an Independent Poor Prognosis Indicator in Lung Adenocarcinoma, but Not in Squamous Cell Carcinoma, Is Associated with an Immunosuppressive Tumor Microenvironment and Distinct Co-Mutational Profiles [0.03%]
PTEN丢失在肺腺癌而非鳞状细胞癌中是一个独立的不良预后指标，且与免疫抑制性肿瘤微环境和不同的共突变谱型相关
Maeva Houry,Shannon J Silva,Maider Artola et al.
Maeva Houry et al.
Background/Objectives: Non-small cell lung cancer (NSCLC) comprises biologically heterogeneous tumors, primarily lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC), which differ in genomic landscape and clinical behavior. Th...
Metabolic Syndrome Is Associated with Greater Symptom Burden and Comorbidity in Chronic Obstructive Pulmonary Disease: A Secondary Analysis of the Serbian COPD Registry [0.03%]
代谢综合征与慢性阻塞性肺疾病患者的症状负担和共病增加有关：来自塞尔维亚慢阻肺登记队列的次级分析研究
Marija Vukoja,Marko Bojović,Ivan Kopitovic et al.
Marija Vukoja et al.
Background: Chronic obstructive pulmonary disease (COPD) and cardiovascular diseases (CVDs) are closely linked through shared inflammatory and metabolic pathways. Metabolic syndrome (MetS), shared by both conditions, may represent a key mec...
Multicenter Study
Medical sciences (Basel, Switzerland). 2026 May 14;14(2):253. DOI:10.3390/medsci14020253 2026
Beyond Clinicopathological Criteria: A Practical Management Framework for Oral Lichen Planus [0.03%]
超越临床病理标准：口腔扁平苔藓的实用管理框架
Doina Iulia Rotaru,Ovidiu Păstrav,Sorana D Bolboacă et al.
Doina Iulia Rotaru et al.
Background: Oral lichen planus (OLP) is a chronic T-cell-mediated inflammatory disorder classified by the World Health Organization as a potentially malignant disorder. Diagnosis remains challenging due to clinical and histopathological ove...
Higher Levels of BRCA1 Gene Methylation in Sporadic Breast Cancer Patients with a Lower Incidence of Recurrence [0.03%]
BRCA1基因甲基化水平较高的散发性乳腺癌患者的复发率较低
Grasiela Agnes,Andrea Pires Souto Damin,Guilherme Watte et al.
Grasiela Agnes et al.
Background: Breast cancer is the most prevalent malignant disease among women. Here, we investigate whether there is an association between disease recurrence in breast cancer patients and the quantitative methylation pattern of seven genes...
Disseminated Intracranial and Spinal Dysembryoplastic Neuroepithelial Tumor: A Case Report with a Systematic Review [0.03%]
弥散性颅内和脊髓发育不良神经上皮瘤一例并系统文献复习
Maksymilian Niemczyk,Justyna Fercho,Oskar G Chasles et al.
Maksymilian Niemczyk et al.
Background: Disseminated intracranial and spinal dysembryoplastic neuroepithelial tumors (DNETs) are exceptionally rare, with only five prior cases reported. Methods: This study presents a case of a 47-year-old woman with DNETs in the right...
Hypophosphatemia in Diabetic Ketoacidosis During Intensive Care Admission [0.03%]
重症监护病房糖尿病酮症酸中毒患者低磷血症的流行率、持续时间和危险因素分析
Nicolas A Sieben,Sebastiaan Blank,Alexis Tabah et al.
Nicolas A Sieben et al.
Introduction: Diabetic ketoacidosis (DKA) is a common complication of diabetes mellitus characterized by metabolic acidosis, ketogenesis, hypovolemia, hyperglycemia, and electrolyte depletion. During treatment of DKA with intravenous fluids...
Multicenter Study
Medical sciences (Basel, Switzerland). 2026 May 12;14(2):249. DOI:10.3390/medsci14020249 2026
Grigory Demyashkin,Mikhail Parshenkov,Sergey Zyryanov et al.
Grigory Demyashkin et al.
Artificial intelligence (AI) is becoming a central driver of change across the drug development lifecycle. However, its integration is evolving so rapidly that it remains essential to understand how these technologies are currently position...
Patient-Reported Quality of Life Predicts First-Cycle Pharmacotherapy Survival in Breast Cancer: A Prospective Cohort Study [0.03%]
患者报告的生活质量可预测乳腺癌患者的首个周期药物生存期：一项前瞻性队列研究
Henry Sutanto,Merlyna Savitri,Een Hendarsih et al.
Henry Sutanto et al.
Objective: Patient-reported outcomes (PROs) provide direct insight into symptom burden and functional status, yet their utility in early pharmacotherapy outcomes in breast cancer remains underexplored. This study investig...
Telerehabilitation and Face-to-Face Exergame Delivery Modalities to Improve Postural Control in Children with Cerebral Palsy: A Randomised Controlled Trial [0.03%]
针对脑瘫儿童改善姿势控制的远程康复与面对面游戏锻炼模式：随机对照试验
Valeska Gatica-Rojas,L Eduardo Cofré Lizama
Valeska Gatica-Rojas
Background: Low-cost virtual reality exergames may help maintain and improve postural control in children with spastic hemiplegia cerebral palsy (CP). This study aimed to evaluate the comparative effectiveness of the same six-week, low-cost...
Randomized Controlled Trial
Medical sciences (Basel, Switzerland). 2026 May 8;14(2):246. DOI:10.3390/medsci14020246 2026