Immunohistochemistry-Based Molecular Profiling of Muscle-Invasive Bladder Cancer: Analysis of 100 Consecutive Cases with Morphological Correlation [0.03%]
基于免疫组化分子分型的肌层浸润性膀胱尿路上皮癌形态学研究(连续100例)
Elitsa Kraevska,Savelina Popovska
Elitsa Kraevska
Background/Objectives: This study aimed to profile the molecular variants of muscle-invasive bladder cancer (MIBC) based on immunohistochemical analysis and to make a correlation with morphological characteristics in a series of 100 consecu...
Efficacy and Safety of VMAT-2 Inhibitors and Dopamine Stabilizers for Huntington's Chorea: A Systematic Review, Meta-Analysis, and Trial Sequential Analysis [0.03%]
亨廷顿舞蹈病VMAT-2抑制剂和多巴胺稳定剂疗效与安全性的系统评价、 meta分析及序贯试验分析
Lautaro Manuel Floridia Rietmann,Candela Romano,Salma Alejandra Beltrán Covarrubias et al.
Lautaro Manuel Floridia Rietmann et al.
Background: Huntington's disease (HD) causes progressive motor dysfunction, with chorea as its hallmark symptom. Vesicular monoamine transporter 2 (VMAT 2) inhibitors (tetrabenazine, deutetrabenazine, valbenazine) are est...
Trends in MitraClip Placements and Predictors of 90-Day Heart Failure Rehospitalization: A Nationwide Analysis [0.03%]
MitraClip置入趋势及90天内因心力衰竭再住院的预测因素全国范围分析
Vivek Joseph Varughese,Vignesh Krishnan Nagesh,Seetharamaprasad Madala et al.
Vivek Joseph Varughese et al.
Background: Chronic mitral regurgitation (MR) is categorized into primary and secondary MR (SMR). While primary MR arises from structural abnormalities of the mitral valve apparatus, SMR is a consequence of cardiac remodeling, typically due...
Efficacy of Tyrosine Kinase Inhibitors in ALK and EGFR-Mutated Non-Small Cell Lung Cancer with Brain Metastases [0.03%]
针对带有脑转移的ALK和EGFR突变非小细胞肺癌的酪氨酸激酶抑制剂疗效分析
Walid Shalata,Rashad Naamneh,Wenad Najjar et al.
Walid Shalata et al.
Background: Brain metastases (BMs) are a common and challenging complication of non-small cell lung cancer (NSCLC), historically associated with a poor prognosis. The development of targeted therapies, specifically tyrosi...
Karn Matangkha,Vichit Punyahotara,Jarasphol Rintra et al.
Karn Matangkha et al.
Background: "Long COVID" refers to a condition in which individuals continue to experience persistent signs and symptoms even after recovering from the initial COVID-19 infection. Signs and symptoms that persist can affec...
Early-Life Environmental Determinants of Allergic Conditions in Children with Atopic Heredity: A Single Center Cross-Sectional Study from Bulgaria [0.03%]
保加利亚一项针对过敏体质儿童过敏状况的环境影响因素的横断面研究
Antoniya Hachmeriyan,Albena Toneva,Miglena Marinova-Achkar et al.
Antoniya Hachmeriyan et al.
Background: Allergic diseases in early childhood are influenced by genetic predisposition and modifiable early-life exposures, including epigenetic mechanisms. Understanding the interplay between environmental factors and...
Visual, Topographic and Aberrometric Outcomes After Phototherapeutic Keratectomy (PTK) for Salzmann Nodular Degeneration [0.03%]
激光角膜切削术治疗Salzmann结节样营养不良的视觉、地形和波前像差结果
Simon Helm,Johanna Wiedemann,Niklas Reinking et al.
Simon Helm et al.
Purpose: The aim of this paper is to study the visual outcomes, changes in higher order aberration (HOA) and corneal densitometry after debridement and excimer laser phototherapeutic keratectomy (PTK) for the treatment of Salzmann nodular d...
Self-Perceived Health Status and Life Satisfaction Associated with Emotional Eating in Nursing and Medical Students: A Cross-Sectional Study in a Region of Peru [0.03%]
秘鲁一地区护理和医学专业学生情绪性饮食与自我感知健康状况和生活满意度相关的横断面研究
Jacksaint Saintila,Ana Valle-Chafloque,Luz A Barreto-Espinoza et al.
Jacksaint Saintila et al.
Background: Emotional eating (EmE) is a maladaptive eating behavior that has been frequently observed among university students, possibly due to academic stress and lifestyle changes. However, its specific assessment in health science stude...
Mast Cell Association with the Microenvironment of a Phosphaturic Mesenchymal Tumour Secreting Fibroblast Growth Factor 23 [0.03%]
与成纤维细胞生长因子23分泌相关的磷尿症性间叶肿瘤微环境中的 mast 细胞浸润关系研究
Andrey Kostin,Alexei Lyundup,Alexander Alekhnovich et al.
Andrey Kostin et al.
Background: Phosphaturic mesenchymal tumours secreting fibroblast growth factor 23 (hereinafter referred to as FGF23+ PMT) are rare neoplasms that can cause hypophosphataemic osteomalacia, owing to excessive FGF23 production. Mast cells (MC...
Computational Identification of RNF114 nsSNPs with Potential Roles in Psoriasis and Immune Dysregulation [0.03%]
计算识别RNF114nsSNPs在银屑病和免疫功能失调中的潜在作用
Ghalia Mahfod Aldoseri,Arwa Ibrahim Alwabran,Ghanem Mahfod Aldoseri et al.
Ghalia Mahfod Aldoseri et al.
Background: RNF114 gene encodes an E3 ubiquitin ligase involved in immune signaling and regulation of inflammation. Genetic variants, particularly nonsynonymous single-nucleotide polymorphisms (nsSNPs), may interfere with...